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Results for "

Contractile response

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

4

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120648A
    CAY 10462 dihydrochloride

    		Cytochrome P450 Cardiovascular Disease
    CAY 10434 dihydrochloride is a potent CYP4A hydroxylase inhibitor. CAY 10434 dihydrochloride improves contractile response to angiotensin II with the maximal contractile response (Emax) 6764 mg .
    CAY 10462 dihydrochloride
  • HY-107610
    SR2640 hydrochloride

    		Leukotriene Receptor Inflammation/Immunology
    SR2640 (hydrochloride) is a potent and selective competitive leukotriene D4/leukotriene E4 antagonist. SR2640 can be used for researching the role of leukotrienes in human asthma .
    SR2640 hydrochloride
  • HY-103291
    Sar-[D-Phe8]-des-Arg9-Bradykinin

    		Bradykinin Receptor Inflammation/Immunology Endocrinology
    Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .
    Sar-[D-Phe8]-des-Arg9-Bradykinin
  • HY-125304
    L 363851

    		Neurokinin Receptor Endocrinology
    L 363851 is a Neurokinin 2 receptor agonist, and induces the contractile response of tracheal smooth muscle devoid of epithelium (IC50 of 3.2 nM) and phosphoinositide hydrolysis (IC50 of 36 μM).
    L 363851
  • HY-117717
    (Rac)-SC-31391

    		Prostaglandin Receptor Others
    (Rac)-SC-31391, a prostaglandin analog, is a strong activator of the bladder muscle contractility that enhanced twitch responses elicited by field stimulation in the guinea pig detrusor muscle. (Rac)-SC-31391 contracts human bladder muscle through the activation of PGF2α receptors .
    (Rac)-SC-31391
  • HY-120648
    CAY 10434

    		Cytochrome P450 Cardiovascular Disease
    CAY 10434 is a potent CYP4A hydroxylase inhibitor. CAY 10434 improves contractile response to angiotensin II with the maximal contractile response (Emax) 6764 mg .
    CAY 10434
  • HY-N9141
    Nantenine

    		5-HT Receptor Neurological Disease
    Nantenine is a serotonergic receptor antagonist. Nantenine selectively inhibits the contractile response of tissues to serotonin. Nantenine can be isolated from Nandina domestica .
    Nantenine
  • HY-P1721
    NPC 17731

    		Bradykinin Receptor Cardiovascular Disease
    NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively .
    NPC 17731
  • HY-105572
    Moveltipril calcium

    MC-838 calcium

    		 Others Cardiovascular Disease
    Moveltipril calcium (MC-838 calcium) is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moveltipril calcium binds via a stable thioester bond and exhibits relative resistance to enzymatic hydrolysis in rat liver homogenate. Moveltipril calcium effectively inhibits ACE extracted from rabbit lung in a concentration-dependent manner. Moveltipril calcium is able to highly specifically inhibit the contractile response to angiotensin-I (AI) in free rat aortic rings and guinea pig ileum preparations, while enhancing the contractile response to calcitonin .
    Moveltipril calcium
  • HY-139801
    Indolapril hydrochloride

    CI-907

    		 Angiotensin-converting Enzyme (ACE) Metabolic Disease
    Indolapril hydrochloride (CI-907) is an orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor. Indolapril hydrochloride is highly specific in suppressing the contractile or pressor responses to Angiotensin I. Indolapril hydrochloride is a potent antihypertensive agent .
    Indolapril hydrochloride
  • HY-19279A
    JTH-601 free base

    		Others Endocrinology
    JTH-601 Free base is a novel alpha1-adrenoceptor antagonist that exhibits potent activity in inhibiting phenylephrine-induced contractions in lower urinary tract tissues. JTH-601 Free base competitively antagonizes alpha1-adrenoceptor-mediated contractile responses, demonstrating greater potency than prazosin or tamsulosin. JTH-601 Free base is anticipated to be effective in treating urinary outlet obstruction associated with benign prostatic hyperplasia.
    JTH-601 free base

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