Search Result

Results for "

ENPP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibody-Drug Conjugates (ADCs) (1) Apoptosis (2) Carbonic Anhydrase (2) PD-1/PD-L1 (1) Phosphodiesterase (PDE) (32) Small Interfering RNA (siRNA) (15) STING (3)
By Research Areas:	Cancer (29) Cardiovascular Disease (1) Infection (7) Inflammation/Immunology (3) Metabolic Disease (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (4) Mouse Pre-designed siRNA Sets (4) Human Pre-designed siRNA Sets (7) siRNAs (15)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-158791

Enpp-1-IN-21	Phosphodiesterase (PDE)	Metabolic Disease Cancer
Enpp-1-IN-21 (compound 4g) is an inhibitor of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), with IC₅₀ values for *ENPP1* and *ENPP3* at 0.45 and 0.19 μM, respectively .

HY-147389

Enpp-1-IN-14	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-14 (Compound 015) is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC₅₀ value of 32.38 nM for recombinant human ENPP-1. Enpp-1-IN-14 has anti-tumor activity .

HY-163343

Enpp-1-IN-20	Phosphodiesterase (PDE) STING	Cancer
Enpp-1-IN-20 (Compound 31) is an ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor, with an IC₅₀ of 0.09 nM. Enpp-1-IN-20 has strongest inhibitory activity in the cell-based assay, with an IC₅₀ of 8.8 nM. Enpp-1-IN-20 has significant potency in both ENPP1 inhibition and STING pathway stimulation in vitro. Enpp-1-IN-20 can be used for the research of cancer .

HY-129490

Enpp-1-IN-1 2 Publications Verification	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-1 is an effective selective *enpp-1* (nucleotide pyrophosphatase-phosphodiesterase 1) inhibitor .

HY-143256

Enpp-1-IN-12	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-12 (compound 43) is a potent and orally active ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1) inhibitor, with a Ki of 41 nM. Enpp-1-IN-12 exhibits anti-tumor activity .

HY-162912

Enpp-1-IN-23	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-23 (compound 27) is an *Enpp-1* inhibitor, with IC₅₀ of 1.2 nM. Enpp-1-IN-23 can be used in cancer research .

HY-147998

Enpp-1-IN-13	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-13 (Compound 1a) is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor with IC₅₀ values of 1.29 μM and 20.2 μM against ENPP1 and ENPP3, respectively. Enpp-1-IN-13 shows anticancer activity .

HY-145062

Enpp-1-IN-4	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-4 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). Enpp-1-IN-4 has the potential for the research of cancer diseases (extracted from patent WO2019177971A1, compound 1) .

HY-153334

Enpp-1-IN-15	Phosphodiesterase (PDE)	Others
Enpp-1-IN-15 (Compound 88a) is an Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (Enpp-1) Inhibitor, with a K_i value of 0.00586 nM .

HY-143255

Enpp-1-IN-11	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-11 (compound 23) is a potent Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1) inhibitor with an K_i value of 45 nM. Enpp-1-IN-11 exhibits low clearance in human and mouse liver microsomes, good plasma stability in human and mouse plasma. Enpp-1-IN-11 can be used for researching anticancer .

HY-168491

Enpp-1-IN-25	Phosphodiesterase (PDE) STING PD-1/PD-L1	Cancer
Enpp-1-IN-25 (Compound 30) is an *ENPP1* inhibitor with an IC₅₀ of 8.05 nM and low oral bioavailability. Enpp-1-IN-25 can effectively activate the intracellular STING pathway by inhibiting cGAMP degradation. Enpp-1-IN-25 can enhance immune cell infiltration in the tumor microenvironment and type I interferon responses, and potentiate the antitumor efficacy of the anti-PD-L1 antibody. Enpp-1-IN-25 can be used in the research of cancer immunotherapy .

HY-153335

Enpp-1-IN-16	Phosphodiesterase (PDE)	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Enpp-1-IN-16 (compound 54) is an *ENPP1* inhibitor. Enpp-1-IN-16 has the potential to study cancer, especially in cases of high ENPP1 expression or elevated cytoplasmic DNA levels. Enpp-1-IN-16 can also be used in other diseases mediated by ENPP1, such as bacterial or viral infections, insulin resistance and type II diabetes, chondrocalcinosis and osteoarthritis, calcium pyrophosphate deposition disorder (CPPD), low Phosphatase disease and soft tissue calcification disorders .

HY-143254

Enpp-1-IN-10	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-10 (compound 1) is a potent Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1) inhibitor with an K_i value of 3.866 μM. Enpp-1-IN-10 can be used for researching anticancer .

HY-155457

Enpp-1-IN-19	Phosphodiesterase (PDE) STING	Cancer
Enpp-1-IN-19 (compound 29f) is an orally active ENPP1 inhibitor that inhibits cGAMP hydrolysis by *ENPP1* (IC₅₀=68 nM). Enpp-1-IN-19 increases anti-PD-L1 responses and inhibits tumor growth in CT26 syngeneic models. Enpp-1-IN-19 also enhances STING-mediated type I interferon responses, induces immune memory, and prevents tumor recurrence .

HY-145065

Enpp-1-IN-7	Phosphodiesterase (PDE)	Infection Cancer
Enpp-1-IN-7 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-7 has the potential for the research of cancer and infectious diseases (extracted from patent WO2021203772A1, compound 51) .

HY-145064

Enpp-1-IN-6	Phosphodiesterase (PDE)	Infection Cancer
Enpp-1-IN-6 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-6 has the potential for the research of cancer and infectious diseases (extracted from patent WO2021203772A1, compound 51) .

HY-145070

Enpp-1-IN-9	Phosphodiesterase (PDE)	Infection Cancer
Enpp-1-IN-9 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-9 has the potential for the research of cancer and infectious diseases (extracted from patent WO2021203772A1, compound 51) .

HY-145069

Enpp-1-IN-8	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-8 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-8 has the potential for the research of cancer and infectious diseases (extracted from patent WO2021203772A1, compound 51) .

HY-162911

Enpp-1-IN-22	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-22 is an orally bioavailable prodrug of the potent *ENPP1* inhibitor paraformaldehyde with antitumor activity .

HY-145063

Enpp-1-IN-5	Phosphodiesterase (PDE)	Infection Inflammation/Immunology Cancer
Enpp-1-IN-5 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-5 has the potential for the research of cancer and infectious diseases (extracted from patent WO2019046778A1/WO2021203772A1, compound 1) .

HY-168147

Enpp-1-IN-24	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-24 (compund 7) is an *ENPP1* inhibitor that, in combination with anti-PD-1 antibodies, achieves 77.7% tumor growth inhibition and improves survival in mouse models .

HY-169804

ENPP3 Inhibitor 1	Phosphodiesterase (PDE)	Cancer
ENPP3 Inhibitor 1 is a selective inhibitor of *ENPP3, with IC₅₀s of 0.15 µM (ENPP3) and 41.4 µM (ENPP1)* respectively. ENPP3 Inhibitor 1 shows anti-tumor activities against breast cancer and cervical cancer .

HY-139362

Enpp-1-IN-2	Phosphodiesterase (PDE)	Cancer
Enpp-1-IN-2 (Compound C) is a potent *ENPP1* (ectonucleotide pyrophosphatase/phosphodiesterase 1) inhibitor with IC₅₀ values of 0.26, 0.48 and 2.0 μM evaluated by means of TG-mAMP, pNP-TMP, and ATP assays, respectively. TG (Tokyo Green)-mAMP: a newly synthesized sensitive ENPP1 fluorescence probe .

HY-153398

Enpp-1-IN-17	Phosphodiesterase (PDE)	Infection Cancer
Enpp-1-IN-17 (example 274) is a potent *ENPP1* inhibitor, with the inhibition constants (Ki values) toward cGAMP and ATP hydrolysis of 100 nM-1 μM and > 1 μM, respectively. The selectivity ratio for inhibition of cGAMP hydrolysis versus ATP hydrolysis is >6.4 .

HY-151917

Enpp/Carbonic anhydrase-IN-2	Apoptosis Carbonic Anhydrase Phosphodiesterase (PDE)	Cancer
Enpp/Carbonic anhydrase-IN-2 (compound 1i) is a potent *Enpp* and carbonic anhydrase inhibitor with IC₅₀s of 1.13, 1.07, 0.74, 0.33, 0.68 for NPP1, NPP2, NPP3, CA-IX, CA-XII respectively. Enpp/Carbonic anhydrase-IN-2 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-2 induces Apoptosis .

HY-151916

Enpp/Carbonic anhydrase-IN-1	Apoptosis Carbonic Anhydrase Phosphodiesterase (PDE)	Cancer
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent *Enpp* and carbonic anhydrase inhibitor with IC₅₀s of 1.36, 1.35, 3.00, 0.88, 1.02 μM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-1 induces Apoptosis .

HY-RS04392

ENPP6 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ENPP6 Human Pre-designed siRNA Set A contains three designed siRNAs for ENPP6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ENPP6 Human Pre-designed siRNA Set A ENPP6 Human Pre-designed siRNA Set A

HY-RS04387

ENPP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ENPP1 Human Pre-designed siRNA Set A contains three designed siRNAs for ENPP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ENPP1 Human Pre-designed siRNA Set A ENPP1 Human Pre-designed siRNA Set A

HY-RS29010

Enpp5 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Enpp5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Enpp5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enpp5 Rat Pre-designed siRNA Set A Enpp5 Rat Pre-designed siRNA Set A

HY-RS17381

Enpp2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Enpp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Enpp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enpp2 Mouse Pre-designed siRNA Set A Enpp2 Mouse Pre-designed siRNA Set A

HY-RS16545

Enpp1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Enpp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Enpp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enpp1 Mouse Pre-designed siRNA Set A Enpp1 Mouse Pre-designed siRNA Set A

HY-RS23836

Enpp2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Enpp2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Enpp2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enpp2 Rat Pre-designed siRNA Set A Enpp2 Rat Pre-designed siRNA Set A

HY-RS04391

ENPP5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ENPP5 Human Pre-designed siRNA Set A contains three designed siRNAs for ENPP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ENPP5 Human Pre-designed siRNA Set A ENPP5 Human Pre-designed siRNA Set A

HY-RS04393

ENPP7 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ENPP7 Human Pre-designed siRNA Set A contains three designed siRNAs for ENPP7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ENPP7 Human Pre-designed siRNA Set A ENPP7 Human Pre-designed siRNA Set A

HY-RS04388

ENPP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ENPP2 Human Pre-designed siRNA Set A contains three designed siRNAs for ENPP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ENPP2 Human Pre-designed siRNA Set A ENPP2 Human Pre-designed siRNA Set A

HY-RS22487

Enpp5 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Enpp5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Enpp5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enpp5 Mouse Pre-designed siRNA Set A Enpp5 Mouse Pre-designed siRNA Set A

HY-RS04389

ENPP3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ENPP3 Human Pre-designed siRNA Set A contains three designed siRNAs for ENPP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ENPP3 Human Pre-designed siRNA Set A ENPP3 Human Pre-designed siRNA Set A

HY-RS24067

Enpp3 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Enpp3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Enpp3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enpp3 Rat Pre-designed siRNA Set A Enpp3 Rat Pre-designed siRNA Set A

HY-RS22977

Enpp1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Enpp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Enpp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enpp1 Rat Pre-designed siRNA Set A Enpp1 Rat Pre-designed siRNA Set A

HY-RS04390

ENPP4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ENPP4 Human Pre-designed siRNA Set A contains three designed siRNAs for ENPP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ENPP4 Human Pre-designed siRNA Set A ENPP4 Human Pre-designed siRNA Set A

HY-RS17607

Enpp3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Enpp3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Enpp3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Enpp3 Mouse Pre-designed siRNA Set A Enpp3 Mouse Pre-designed siRNA Set A

HY-171544

AGS-16C3F AGS-16M8F	Antibody-Drug Conjugates (ADCs) Phosphodiesterase (PDE)	Cancer
AGS-16C3F is an antibody-drug conjugate (ADC) targeting ENPP3. AGS-16C3F is composed of ENPP3-targeting Anti-ENPP3/CD203c Antibody (HY-P990315) linked to Monomethyl auristatin F (HY-15579) via a linker. AGS-16C3F has anti-tumor activity and can be used in the study of metastatic renal cell carcinoma (mRCC) .

HY-157522

NCI-14465	Phosphodiesterase (PDE)	Cancer
NCI-14465 is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP1) inhibitor with an IC 50 of 26.4 μM. NCI-14465 can be used in cancer research .

HY-145344

ONO-8430506	Phosphodiesterase (PDE)	Cancer
ONO-8430506 is an orally bioavailable and potent autotaxin (ATX)/ENPP2 inhibitor with the IC₉₀ of 100 nM for ATX activity in mouse plasma .

HY-143237

ATX inhibitor 11	Phosphodiesterase (PDE)	Others
ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC₅₀ of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research .

HY-156205

CdnP-IN-1	Phosphodiesterase (PDE)	Infection
CdnP-IN-1 (compound c82) is a potent and selective non-nucleotide *MTB CDN PDE (CdnP; Mycobacterium tuberculosis* cyclic dinucleotide phosphodiesterase) inhibitor with an IC₅₀** of 18 μM. CdnP-IN-1 does not inhibit the enzymatic activities of three other bacterial CDN PDEs (Yybt, RocR, and GBS-CdnP), a viral CDN PDE (poxin) or mammalian ENPP1 .

HY-143582

ATX inhibitor 9	Phosphodiesterase (PDE)	Cancer
ATX inhibitor 9 is a potent inhibitor of ATX. ATX inhibitor 9 is a thickened heteroaryl derivatives compound. Autotaxin (ATX), also known as ENPP2, is a secreted enzyme that is highly expressed mainly in cancer cells, bronchial epithelial cells and alveolar macrophages in the lung. ATX inhibitor 9 has the potential for the research of cancer or fibrous degenerative disease (extracted from patent WO2021078227A1, compound 3) .

Cat. No.	Product Name	Target	Research Area

HY-P990315

*Anti-ENPP3/CD203c Antibody (AGS-16C3F antibody)* AGS-16C	Inhibitory Antibodies	Inflammation/Immunology
Anti-ENPP3/CD203c Antibody (AGS-16C3F antibody) is a humanized antibody expressed in CHO cells, targeting *ENPP3/CD203c. Anti-ENPP3/CD203c Antibody contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 154.04 kDa. The isotype control for Anti-ENPP*3/CD203c Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

Species:	Human (10) Rhesus Macaque (1) Mouse (4) Cynomolgus (2) Canine (1)
Tag:	His (18) Avi (4)
Source:	HEK293 (17) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P700438

	ENPP-3 Protein, Macaca fascicularis (HEK293, His) E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6	Cynomolgus	HEK293
	ENPP3 is a hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP, and CTP, and plays a key role in immune regulation. It modulates mast cell and basophil responses during inflammation and chronic allergic phases by eliminating extracellular ATP, a trigger for inflammatory cytokine release. ENPP-3 Protein, Macaca fascicularis (HEK293, His) is the recombinant cynomolgus-derived ENPP3 protein, expressed by HEK293 , with N-10*His labeled tag.

HY-P78705

	ENPP-3 Protein, Mouse (HEK293, His) ENPP3; CD203c; NPP3; E-NPP3; PD-Ibeta; NPPase; PDNP3	Mouse	HEK293
	ENPP-3 is a hydrolase that metabolizes extracellular nucleotides (ATP, GTP, UTP, CTP), which is critical for immune regulation of inflammation and chronic allergic reactions. By eliminating extracellular ATP, ENPP-3 inhibits basophil and mast cell activation and suppresses the release of inflammatory cytokines. ENPP-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ENPP-3 protein, expressed by HEK293 , with N-10*His labeled tag.

HY-P700410

	ENPP-3 Protein, Human (828a.a, HEK293, His) E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6	Human	HEK293
	ENPP3 is a hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP, and CTP, and plays a key role in immune regulation. It modulates mast cell and basophil responses during inflammation and chronic allergic phases by eliminating extracellular ATP, a trigger for inflammatory cytokine release. ENPP3 Protein, Human (828a.a, HEK293, His) is the recombinant human-derived ENPP3 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P70167

	ENPP-2 Protein, Human (HEK293, His) rHuEctonucleotide phosphodiesterase family member 2/ENPP-2, His ; ATX; ATXFLJ26803; ATX-X; Autotaxin; autotaxin-t; EC 3.1.4.39; ectonucleotide pyrophosphatase/phosphodiesterase 2; E-NPP 2; ENPP2; LysoPLD; NPP2; PD-IALPHA; PDNP2; PDNP2NPP2	Human	HEK293
	The ENPP-2 protein catalyzes the hydrolysis of lysophospholipids (especially lysophosphatidylcholine) to produce the signaling molecule lysophosphatidic acid (LPA). It also acts on sphingosine phosphocholine to produce sphingosine 1-phosphate, which affects cell movement. ENPP-2 Protein, Human (HEK293, His) is the recombinant human-derived ENPP-2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77923

	ENPP-1 Protein, Human (HEK293, His) E-NPP 1; NPPase; ENPP1; NPPS; PC1; PDNP1; Ly-41 Antigen; M6S1; M6S1NPP1; NPP1; PCA1; PCA1ARHR2	Human	HEK293
	ENPP-1 protein is a nucleotide pyrophosphatase that inhibits excessive hydroxyapatite crystal growth by preferentially hydrolyzing ATP and other nucleoside triphosphates to generate PPi, thereby critically regulating bone mineralization and soft tissue calcification. ENPP-1 Protein, Human (HEK293, His) is the recombinant human-derived ENPP-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700710

	ENPP-3 Protein, Canine (HEK293, His) E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6; PD-Iβ	Canine	HEK293
	ENPP-3 is a hydrolase that plays a crucial role in regulating the immune response. ENPP-3 plays an important role in tumor development and invasion. The hypomethylation of the ENPP-3 promoter region is involved in the occurrence and progression of ovarian endometriosis through the AKT/mTOR/4EBP1 signaling pathway. ENPP-3 Protein, Canine (HEK293, His) is the recombinant canine-derived ENPP-3 protein, expressed by HEK293 , with N-His labeled tag.

HY-P77928

	ENPP-3 Protein, Human (318a.a, HEK293, His) E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6	Human	HEK293
	ENPP3 is a hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP, and CTP, and plays a key role in immune regulation. It modulates mast cell and basophil responses during inflammation and chronic allergic phases by eliminating extracellular ATP, a trigger for inflammatory cytokine release. ENPP-3 Protein, Human (318a.a, HEK293, His) is the recombinant human-derived ENPP-3 protein, expressed by HEK293 , with N-His labeled tag.

HY-P77926

	ENPP-3 Protein, Human (110a.a, HEK293, His-Avi) E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6	Human	HEK293
	ENPP3 is a hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP, and CTP, and plays a key role in immune regulation. It modulates mast cell and basophil responses during inflammation and chronic allergic phases by eliminating extracellular ATP, a trigger for inflammatory cytokine release. ENPP-3 Protein, Human (110a.a, HEK293, His-Avi) is the recombinant human-derived ENPP-3 protein, expressed by HEK293 , with N-His, N-Avi labeled tag.

HY-P77925

	ENPP-3 Protein, Human (Biotinylated, 828a.a, HEK293, His-Avi) E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6	Human	HEK293
	ENPP3 is a hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP, and CTP, and plays a key role in immune regulation. It modulates mast cell and basophil responses during inflammation and chronic allergic phases by eliminating extracellular ATP, a trigger for inflammatory cytokine release. ENPP-3 Protein, Human (Biotinylated, 828a.a, HEK293, His-Avi) is the recombinant human-derived ENPP-3 protein, expressed by HEK293 , with N-His, N-Avi labeled tag.

HY-P77927

	ENPP-3 Protein, Human (Biotinylated, 110a.a, HEK293, His-Avi) E-NPP 3; NPP3; PD-Ibeta; NPPase; ENPP3; PDNP3; CD203c; B10; gp130RB13-6	Human	HEK293
	ENPP3 is a hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP, and CTP, and plays a key role in immune regulation. It modulates mast cell and basophil responses during inflammation and chronic allergic phases by eliminating extracellular ATP, a trigger for inflammatory cytokine release. ENPP-3 Protein, Human (Biotinylated, 110a.a, HEK293, His-Avi) is the recombinant human-derived ENPP-3 protein, expressed by HEK293 , with N-His, N-Avi labeled tag.

HY-P700709

	ENPP-1 Protein, Mouse (HEK293, His) E-NPP 1; NPPase; ENPP1; NPPS; PC1; PDNP1; Ly-41 Antigen; M6S1; M6S1NPP1; NPP1; PCA1; PCA1ARHR2	Mouse	HEK293
	ENPP-1 is a nucleotide pyrophosphatase that critically regulates bone mineralization and soft tissue calcification through the production of diphosphate (PPi).This PPi inhibits the growth of hydroxyapatite crystals and prevents unwanted mineralization.ENPP-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ENPP-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700956

	ENPP-1 Protein, Human (Biotinylated, HEK293, His-Avi) E-NPP 1; NPPase; ENPP1; NPPS; PC1; PDNP1; Ly-41 Antigen; M6S1; M6S1NPP1; NPP1; PCA1; PCA1ARHR2	Human	HEK293
	ENPP-1 protein is a nucleotide pyrophosphatase that inhibits excessive hydroxyapatite crystal growth by preferentially hydrolyzing ATP and other nucleoside triphosphates to generate PPi, thereby critically regulating bone mineralization and soft tissue calcification. ENPP-1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived ENPP-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P75734

	ENPP-5 Protein, Human (HEK293, His) Ectonucleotide pyrophosphatase/phosphodiesterase family member 5; NPP-5	Human	HEK293
	ENPP-5, also known as ectonucleotide pyrophosphatase/phosphodiesterase 5, has the ability to hydrolyze nicotinamide adenine dinucleotide (NAD) but does not have lysophospholipase D activity, indicating its inability to hydrolyze Nucleotide diphosphates and triphosphates. This enzymatic activity suggests that ENPP-5 may play a role in regulating NAD levels and possibly affecting cellular processes involved in NAD metabolism. ENPP-5 Protein, Human (HEK293, His) is the recombinant human-derived ENPP-5 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76902

	ENPP-7 Protein, Mouse (HEK293, His) Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; NPP-7; Alk-Smase	Mouse	HEK293
	The ENPP-7 protein acts as a choline-specific phosphodiesterase and is essential for sphingomyelin digestion, ceramide formation, and FA absorption in the gastrointestinal tract. It hydrolyzes sphingomyelin to release ceramide and phosphocholine. ENPP-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ENPP-7 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77358

	ENPP-7 Protein, Human (HEK293, His) Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; NPP-7; Alk-Smase	Human	HEK293
	The ENPP-7 protein is a choline-specific phosphodiesterase that plays multiple roles in sphingomyelin digestion, ceramide formation, and fatty acid absorption in the gastrointestinal tract. It hydrolyzes sphingomyelin, releases ceramide and phosphocholine, and promotes the breakdown of sphingomyelin. ENPP-7 Protein, Human (HEK293, His) is the recombinant human-derived ENPP-7 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75733

	ENPP-2 Protein, Mouse (HEK293, His) Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Autotaxin; LysoPLD; Npps2; Pdnp2	Mouse	HEK293
	The ENPP-2 protein catalyzes the hydrolysis of lysophospholipids (especially lysophosphatidylcholine) to produce the signaling molecule lysophosphatidic acid (LPA).It also acts on sphingosine phosphocholine to produce sphingosine 1-phosphate, which affects cell movement.ENPP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ENPP-2 protein, expressed by HEK293 , with N-His, N-10*His labeled tag.

HY-P703781

	ENPP-2 Protein, Cynomolgus (HEK293, His) Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Autotaxin; LysoPLD; Npps2; Pdnp2	Cynomolgus	HEK293

HY-P77357

	ENPP-3 Protein, Rhesus Macaque (sf9, His) Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; NPP3; PD-Ibeta; PDNP3	Rhesus Macaque	Sf9 insect cells
	ENPP-3 is a hydrolase that metabolizes extracellular nucleotides (ATP, GTP, UTP, CTP), which is critical for immune regulation of inflammation and chronic allergic reactions. By eliminating extracellular ATP, ENPP-3 inhibits basophil and mast cell activation and suppresses the release of inflammatory cytokines. ENPP-3 Protein, Rhesus Macaque (sf9, His) is the recombinant Rhesus Macaque-derived ENPP-3 protein, expressed by Sf9 insect cells , with N-His labeled tag.

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HY-P83803

	CD203C Antibody (YA3500) ENPP3; B10; NPP3; PDNP3; PD-IBETA	IHC-P, FC, ELISA	Human

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