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Results for "

GM3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Biochemical Assay Reagents (2) Endogenous Metabolite (1) Ferroptosis (1) Insulin Receptor (2) Isotope-Labeled Compounds (4) Sialyltransferase (1) VEGFR (1)
By Research Areas:	Cancer (1) Infection (1) Metabolic Disease (4) Neurological Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-114456

Ganglioside GM3	Insulin Receptor	Metabolic Disease
Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia .

HY-165160

*N-Glycolyl-ganglioside GM3* ammonium** GM3-Neugc ammonium; NeuGc-GM3 ammonium	Biochemical Assay Reagents	Others
N-Glycolyl-ganglioside GM3 ammonium is a biochemical reagent.

HY-W342441

*Monosialoganglioside GM3* (bovine)**	VEGFR Akt Ferroptosis Insulin Receptor	Metabolic Disease Cancer
Monosialoganglioside GM3 (bovine) is a monosialoganglioside and an inhibitor of VEGFR2 and Akt. At a concentration of 20 μM, Monosialoganglioside GM3 inhibits angiogenesis and reduces the proliferation and migration of human umbilical vein endothelial cells (HUVECs) by inhibiting VEGFR2 and Akt phosphorylation. Ganglioside GM3 also inhibits ferroptosis, providing protective effects during the formation of abdominal aortic aneurysms. Additionally, Monosialoganglioside GM3 (bovine) acts as an inhibitor of insulin signaling, inducing the dissociation of the insulin receptor (IR)-Caveolin-1 complex from lipid microdomains and causing insulin resistance in adipocytes. Monosialoganglioside GM3 (bovine) can be used in cancer and metabolic disease research .

HY-W127324

*Ganglioside GM3* (phyto-type)** NeuAcα(2-3)Galβ(1-4)Glc-ceramide (phyto-type)	Biochemical Assay Reagents	Others
Ganglioside GM3 (phyto-type) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-114456S

*Ganglioside GM3-d7*	Isotope-Labeled Compounds Others	Metabolic Disease
Ganglioside GM3-d₇ is deuterium labeled Ganglioside GM3. Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia ^[3].

HY-152002S

*Ganglioside GM3-d3 ammonium*	Isotope-Labeled Compounds	Others
Ganglioside GM3-d3 ammonium is a deuterated labeled Ganglioside GM3 ammonium .

HY-114456AS

*Ganglioside GM3-d5 Bovine Milk ammonium salt*	Isotope-Labeled Compounds	Others
Ganglioside GM3-d₅ (Bovine Milk ammonium salt) is deuterium labeled Ganglioside GM3 (Bovine Milk ammonium salt).

HY-165665S

*C16 Ganglioside GM3-d9 ammonium salt*	Isotope-Labeled Compounds	Others
C16 Ganglioside GM3-d₉ (ammonium salt) is deuterium labeled C16 Ganglioside GM3 (ammonium salt) .

HY-E70065

alpha-2,3-Sialyltransferase (PmST2)	Sialyltransferase	Infection
alpha-2,3-Sialyltransferase (PmST2) is a sialyltransferase produced by Pasteurella multocida (Pm) and plays an important role in the pathogenesis of Pm. alpha-2,3-Sialyltransferase (PmST2) can be used to synthesize sialyllactosyl sphingosine (lyso-GM3) .

HY-131701

Lactosyl-C18-sphingosine C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine; Lyso-Lactosylceramide (synthetic)	Endogenous Metabolite	Metabolic Disease
Lactosyl-C18-sphingosine (C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine) is a bioactive sphingolipid that is a form of lactosylceramide but lacks the fatty acyl group. Lysolactosylceramide (1-50 μM) reduces the viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosyl-C18-sphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosyl-C18-sphingosine is a lysoganglioside GM3.

HY-E70049

beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) GM2/GD2 synthase	Others	Neurological Disease
beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) (GM2/GD2 synthase) is a key enzyme which catalyzes the conversion of GM3, GD3 and lactosylceramide (LacCer) to GM2, GD2 and asialo-GM2 (GA2), respectively. beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) is a key enzyme to control the synthesis of brain-enriched complex gangliosides .

HY-N10512

Gangliotetraose Gg4	Others	Neurological Disease
Gangliotetraose (Gg4) is a tetrasccharide, exhibits major components including GM1 and its sialylated derivatives. GM1 facilitates efflux of nuclear Ca ²⁺ and reduces the level of nuclear Ca ²⁺ that characterizes the differentiated neuron. GM1 affects neuronal plasticity and repair mechanisms, as well as neurotrophin release in the brain .

*Ganglioside GM3* (phyto-type)** NeuAcα(2-3)Galβ(1-4)Glc-ceramide (phyto-type)	Biochemical Assay Reagents
Ganglioside GM3 (phyto-type) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N10512

Gangliotetraose Gg4	Structural Classification Polysaccharides Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Saccharides	Others
Gangliotetraose (Gg4) is a tetrasccharide, exhibits major components including GM1 and its sialylated derivatives. GM1 facilitates efflux of nuclear Ca ²⁺ and reduces the level of nuclear Ca ²⁺ that characterizes the differentiated neuron. GM1 affects neuronal plasticity and repair mechanisms, as well as neurotrophin release in the brain .

Cat. No.	Product Name	Chemical Structure

HY-114456S

*Ganglioside GM3-d7*
Ganglioside GM3-d₇ is deuterium labeled Ganglioside GM3. Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia ^[3].

Ganglioside GM3-d7

Ganglioside GM3-d₇ is deuterium labeled Ganglioside GM3. Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia ^[3].

HY-152002S

*Ganglioside GM3-d3 ammonium*
Ganglioside GM3-d3 ammonium is a deuterated labeled Ganglioside GM3 ammonium .

HY-114456AS

*Ganglioside GM3-d5 Bovine Milk ammonium salt*
Ganglioside GM3-d₅ (Bovine Milk ammonium salt) is deuterium labeled Ganglioside GM3 (Bovine Milk ammonium salt).

HY-165665S

*C16 Ganglioside GM3-d9 ammonium salt*
C16 Ganglioside GM3-d₉ (ammonium salt) is deuterium labeled C16 Ganglioside GM3 (ammonium salt) .

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