Search Result
Results for "
Glucuronic acid
" in MedChemExpress (MCE) Product Catalog:
12
Biochemical Assay Reagents
6
Isotope-Labeled Compounds
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Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N6612B
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Bacterial
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Inflammation/Immunology
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Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. Glucuronic acid sodium also enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Furthermore, Glucuronic acid sodium plays a role in modulating gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
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- HY-41982
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D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone
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Endogenous Metabolite
Drug Derivative
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Cardiovascular Disease
Metabolic Disease
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D-Glucuronic acid lactone (D-Glucurono-6,3-lactone) is an endogenous metabolite, which is a glucuronic acid derivative. D-Glucuronic acid lactone can be used as starting regents in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, requirement for the preparation of 1-O-acyl glucuronide of the anti-inflammatory agent ML-3000 (HY-B1452), synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. D-Glucuronic acid lactone is promising for research of reversible cerebral vasoconstriction syndrome (RCVS) .
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- HY-N6612A
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- HY-N6612R
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Reference Standards
Endogenous Metabolite
Toll-like Receptor (TLR)
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Metabolic Disease
Inflammation/Immunology
Cancer
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D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid. This product is intended for research and analytical applications. D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity .
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- HY-N6612
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Endogenous Metabolite
Toll-like Receptor (TLR)
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Metabolic Disease
Inflammation/Immunology
Cancer
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D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity .
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- HY-W008125
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Acetobromo-alpha-D-Glucuronic acid methyl ester, 98%
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Biochemical Assay Reagents
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Others
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Acetobromo-α-D-glucuronic acid methyl ester, 98% (Acetobromo-alpha-D-glucuronic acid methyl ester, 98%) can be used in glycobiology research and can undergo glycosylation reactions with suitable glycoside receptors.
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- HY-125954
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UDP-α-D-Glucuronic acid
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Endogenous Metabolite
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Metabolic Disease
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Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
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- HY-125954A
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UDP-α-D-Glucuronic acid ammonium
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Endogenous Metabolite
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Metabolic Disease
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Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
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- HY-N6612S
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- HY-125954S
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UDP-α-D-Glucuronic acid-13C,15N2
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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Uridine diphosphate glucuronic acid- 13C, 15N2 (UDP-α-D-glucuronic acid- 13C, 15N2) is the 13C- and 15N-labeled Uridine diphosphate glucuronic acid (HY-125954). Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
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- HY-153179
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Drug-Linker Conjugates for ADC
Topoisomerase
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Cancer
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Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for Antibody-Drug Conjugates (ADCs) synthesis. Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for research of tumor research and diagnosis .
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- HY-143421
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CMG
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Drug Metabolite
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Cancer
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Curcumin monoglucuronide is known as a glucuronic acid conjugate, which is one of the in vivo metabolites of curcumin. Curcumin monoglucuronide is used for research on the metabolism of curcumin and examination of its development as a pharmaceutical. Curcumin monoglucuronide has the potential for the research of cancer disease (extracted from patent WO2022004873A1) .
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- HY-W357152
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- HY-160885A
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ADC Cytotoxin
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Cancer
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NH2-Gly-PAB-Exatecan-D-glucuronic acid formic (Compound 8) is the formic salt form of H2N-Gly-PAB-Exatecan-D-glucuronic acid. H2N-Gly-PAB-Exatecan-D-glucuronic acid formic is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
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- HY-N7033R
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Uridine 5'-diphosphoGlucuronic acid trisodium salt (Standard)
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Reference Standards
Drug Intermediate
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Metabolic Disease
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UDP-glucuronic acid (trisodium) (Standard) is the analytical standard of UDP-glucuronic acid (trisodium). This product is intended for research and analytical applications. UDP-?glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
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- HY-160885
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ADC Cytotoxin
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Others
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NH2-Gly-PAB-Exatecan-D-glucuronic acid (Compound 8) is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
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- HY-E70423
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Biochemical Assay Reagents
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Others
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UDP-glucuronic acid decarboxylase is a decarboxylase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .
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- HY-N9412
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Others
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Others
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4-O-Methyl-D-glucuronic acid is a kind of hemicellulose that can be isolated from the holocellulose of the Ganpi bast fibers .
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- HY-137134
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- HY-132031
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Drug-Linker Conjugates for ADC
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Cancer
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Mal-Val-Ala-PAB(C2-glucuronic acid)-DMEA-PNU-159682 is an active molecule-conjugate for ADCs, composed of a cleavable Val-Ala linker and the potent ADC cytotoxic payload PNU-159682 (HY-16700) .
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- HY-41982R
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D-Glucurono-6,3-lactone (Standard); D-Glucurono-γ-lactone (Standard); D-Glucuronolactone (Standard); Dicurone (Standard); Glucoxy (Standard); Glucurolactone (Standard); Glucurone (Standard)
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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D-Glucuronic acid lactone (Standard) is the analytical standard of D-Glucuronic acid lactone. This product is intended for research and analytical applications. D-Glucuronic acid lactone is an endogenous metabolite.
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- HY-N7033
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Uridine 5'-diphosphoGlucuronic acid trisodium salt
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Drug Intermediate
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Metabolic Disease
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UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
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- HY-W008125S
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Methyl acetobromo-α-D-glucuronate-13C6 methyl ester
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Isotope-Labeled Compounds
Biochemical Assay Reagents
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Others
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Acetobromo-a-D-glucuronic acid- 13C6 methyl ester (Methyl acetobromo-α-D-glucuronate- 13C6 methyl ester) is 13C labeled Acetobromo-α-D-glucuronic acid methyl ester, 98%. Acetobromo-α-D-glucuronic acid methyl ester, 98% (Acetobromo-alpha-D-glucuronic acid methyl ester, 98%) can be used in glycobiology research and can undergo glycosylation reactions with suitable glycoside receptors.
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- HY-W699702
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Biochemical Assay Reagents
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Others
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D-Glucuronic acid,methyl ester,2,3,4-tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W048546
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Methyl-(2,3,4-tri-O-acetyl-a-D-glucopyranosyl)uronate
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Biochemical Assay Reagents
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2,3,4-Tri-O-acetyl-α-D-glucuronic acid methyl ester is a Biochemical Assay Reagent, and can be used for chemical synthesis .
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- HY-W403047
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Biochemical Assay Reagents
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Others
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Methyl 2,3,4-Tri-O-benzyl-α-D-glucuronic Acid, Benzyl Ester is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W794390
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Biochemical Assay Reagents
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Others
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2,3,4-Tri-O-benzoyl-α-D-glucuronic acid methyl ester,trichloroacetimidate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W714797
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Isotope-Labeled Compounds
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Others
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Nintedanib demethyl-O-glucuronic acid-d3 is the deuterium labeled (2R,3R,4R,5S,6S)-3,4,5-Trihydroxy-6-(((Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carbonyl)oxy)tetrahydro-2H-pyran-2-carboxylic acid (HY-W712456).
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- HY-W412723
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β-D-Glucopyranuronic acid tetraacetate
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Biochemical Assay Reagents
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1,2,3, 4-tetra-o-acetyl-β-d-glucuronic acid (β-D-Glucopyranuronic acid tetraacetate) is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
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- HY-W039890
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Biochemical Assay Reagents
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Others
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1-(2,2,2-Trifluoro-N-phenylacetimidate)-2,3,4-tri-?O-acetyl-D-glucuronic acid methyl ester is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-E70035
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Endogenous Metabolite
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Metabolic Disease
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Glucuronokinase (AtGlcAK) is a member of the GHMP-kinase. Glucuronokinase (AtGlcAK) shows unique substrate specificity for D-glucuronic acid with a Km value of 0.7 mM. Glucuronokinase (AtGlcAK) catalyzes D-glucuronic acid and ATP to produce D-glucuronic acid-1-phosphate and ADP .
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- HY-155944
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Phosphodiesterase (PDE)
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Inflammation/Immunology
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Isbufylline is a Phosphodiesterase inhibitor. Isbufylline is orally available. Isbufylline can be used in the research of respiratory diseases and inflammation such as asthma and pneumonia.
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- HY-W145597
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- HY-N7700A
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- HY-P2803B
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β-glucuronidase
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Metabolic Disease
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Beta-glucuronidase (helix pomatia) is a glycosyl hydrolase that hydrolyzes β-glucuronic acid and sulfate esters in urine and other biological fluids, and then releases β-glucuronate .
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- HY-N7755
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Estrogen Receptor/ERR
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Cancer
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Estradiol 3-(β-D-Glucuronide) sodium is the glucuronic acid derivative of estradiol (HY-B0141). Estradiol 3-(β-D-Glucuronide) sodium is radiolabeled for use in tumor imaging and biodistribution studies .
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- HY-N6740
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Apoptosis
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Metabolic Disease
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Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .
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- HY-E70179
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EC 2.4.1.149; B4GAT1; β3GNTI
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Glucosylceramide Synthase (GCS)
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Others
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beta-1,4-Glucuronyltransferase 1 is a glucosyltransferase. beta-1,4-Glucuronyltransferase 1 transfers glucuronic acid towards both α and β anomers of xylose .
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- HY-128747A
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- HY-128747
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- HY-E70020
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Others
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Others
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UDP-Glc dehydrogenase (UGDH) catalyzes is a NAD+-dependent enzyme that catalyzes the two-fold oxidation of UDP-glucose (UDP-Glc) to produce UDP-glucuronic acid. UDP-Glc dehydrogenase (UGDH) is a key enzyme in the nucleotide-sugar interconversion pathway necessary for biosynthesis of many cell-wall polysaccharides .
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- HY-128749
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Potassium D-glucarate
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Endogenous Metabolite
Apoptosis
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Metabolic Disease
Inflammation/Immunology
Cancer
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D-Glucaric acid potassium (Potassium D-glucarate) is an orally active end product of the D-glucuronic acid pathway in mammals. D-Glucaric acid potassium is present in a variety of fruits and vegetables. D-Glucaric acid potassium has cholesterol-lowering and anti-tumor activities. D-Glucaric acid potassium can inhibit tumor cell proliferation and inflammation, and induce apoptosis .
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- HY-N9522
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Endogenous Metabolite
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Others
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β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)-βD-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene28-oate, as a saponin, has a glucuronic acid attached to carbon C-3 and is isolated from S. simplex .
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![β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)-βD-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene28-oate](//file.medchemexpress.eu/product_pic/hy-n9522.gif)
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- HY-N11976
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Others
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Others
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Glycyrrhizin-6′′-methylester (compound 22) is a glycyrrhizin that can be isolated from licorice root. Glycyrrhizin-6′′-methylester can participate as an aglycone in the formation of methyl glucuronate, producing a sweet and licorice taste, but no bitterness. This reveals the importance of the free carboxyl group on the glycoside cone-bound glucuronic acid for natural sweetness and licorice taste .
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- HY-N6740S
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Isotope-Labeled Compounds
Apoptosis
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Metabolic Disease
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β-Zearalanol-d4 is a deuterium labeled Beta-Zearalanol (HY-N6740） . Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .
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- HY-128749A
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Calcium D-glucarate tetrahydrate
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Endogenous Metabolite
Apoptosis
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Metabolic Disease
Inflammation/Immunology
Cancer
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D-Glucaric acid tetrahydrate (Calcium D-glucarate tetrahydrate) is an orally active end product of the D-glucuronic acid pathway in mammals. D-Glucaric acid tetrahydrate is present in a variety of fruits and vegetables. D-Glucaric acid tetrahydrate has cholesterol-lowering and anti-tumor activities. D-Glucaric acid tetrahydrate can inhibit tumor cell proliferation and inflammation, and induce apoptosis .
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- HY-W041019
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Endogenous Metabolite
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Metabolic Disease
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5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse .
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- HY-D1578
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Fluorescent Dye
β-glucuronidase
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Others
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C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm) .
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- HY-W752886
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Isotope-Labeled Compounds
Estrogen Receptor/ERR
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Cancer
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Estradiol 3-d3 (β-D-Glucuronide) sodium is the deuterium labeled Estradiol 3-(β-D-Glucuronide) sodium (HY-N7755). Estradiol 3-(β-D-Glucuronide) sodium is the glucuronic acid derivative of estradiol (HY-B0141). Estradiol 3-(β-D-Glucuronide) sodium is radiolabeled for use in tumor imaging and biodistribution studies .
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- HY-128747R
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Reference Standards
Endogenous Metabolite
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Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
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α-D-Glucose-1-phosphate disodium (Standard) is the analytical standard of α-D-Glucose-1-phosphate disodium (HY-128747). This product is intended for research and analytical applications.
α-D-Glucose-1-phosphate disodium is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element.
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- HY-128749AR
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Calcium D-glucarate tetrahydrate (Standard)
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Endogenous Metabolite
Reference Standards
Apoptosis
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Metabolic Disease
Inflammation/Immunology
Cancer
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D-Glucaric acid tetrahydrate (Standard) (Calcium D-glucarate tetrahydrate (Standard)) is the analytical standard of D-Glucaric acid tetrahydrate (HY-128749A). This product is intended for research and analytical applications. D-Glucaric acid tetrahydrate (Calcium D-glucarate tetrahydrate) is an orally active end product of the D-glucuronic acid pathway in mammals. D-Glucaric acid tetrahydrate is present in a variety of fruits and vegetables. D-Glucaric acid tetrahydrate has cholesterol-lowering and anti-tumor activities. D-Glucaric acid tetrahydrate can inhibit tumor cell proliferation and inflammation, and induce apoptosis .
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Product Name |
Type |
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- HY-D1578
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Fluorescent Dyes/Probes
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C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm) .
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| Cat. No. |
Product Name |
Type |
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- HY-W008125
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Acetobromo-alpha-D-Glucuronic acid methyl ester, 98%
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Carbohydrates
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Acetobromo-α-D-glucuronic acid methyl ester, 98% (Acetobromo-alpha-D-glucuronic acid methyl ester, 98%) can be used in glycobiology research and can undergo glycosylation reactions with suitable glycoside receptors.
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- HY-W048546
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Methyl-(2,3,4-tri-O-acetyl-a-D-glucopyranosyl)uronate
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Carbohydrates
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2,3,4-Tri-O-acetyl-α-D-glucuronic acid methyl ester is a Biochemical Assay Reagent, and can be used for chemical synthesis .
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- HY-125954A
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UDP-α-D-Glucuronic acid ammonium
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Gene Sequencing and Synthesis
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Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
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- HY-W357152
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Carbohydrates
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2-Naphthyl-β-D-glucuronic acid sodium can be used in glycobiology research.
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- HY-137134
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Carbohydrates
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D-Glucuronic acid,2-propen-1-yl ester is a biochemical assay reagent.
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- HY-W699702
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Carbohydrates
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D-Glucuronic acid,methyl ester,2,3,4-tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W403047
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Carbohydrates
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Methyl 2,3,4-Tri-O-benzyl-α-D-glucuronic Acid, Benzyl Ester is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W794390
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Carbohydrates
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2,3,4-Tri-O-benzoyl-α-D-glucuronic acid methyl ester,trichloroacetimidate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W412723
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β-D-Glucopyranuronic acid tetraacetate
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Carbohydrates
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1,2,3, 4-tetra-o-acetyl-β-d-glucuronic acid (β-D-Glucopyranuronic acid tetraacetate) is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
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- HY-W039890
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Carbohydrates
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1-(2,2,2-Trifluoro-N-phenylacetimidate)-2,3,4-tri-?O-acetyl-D-glucuronic acid methyl ester is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-E70168
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EC:2.8.2.-; CHST10; huHNK-1ST
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Enzyme Substrates
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Carbohydrate Sulfotransferase 10 (EC:2.8.2.-) can catalyze sulphate transfer to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides .
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- HY-E70179
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EC 2.4.1.149; B4GAT1; β3GNTI
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Enzyme Substrates
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beta-1,4-Glucuronyltransferase 1 is a glucosyltransferase. beta-1,4-Glucuronyltransferase 1 transfers glucuronic acid towards both α and β anomers of xylose .
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Product Name |
Category |
Target |
Chemical Structure |
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- HY-41982
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D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone
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Structural Classification
Microorganisms
Classification of Application Fields
Ketones, Aldehydes, Acids
Source classification
Metabolic Disease
Endogenous metabolite
Disease Research Fields
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Endogenous Metabolite
Drug Derivative
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D-Glucuronic acid lactone (D-Glucurono-6,3-lactone) is an endogenous metabolite, which is a glucuronic acid derivative. D-Glucuronic acid lactone can be used as starting regents in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, requirement for the preparation of 1-O-acyl glucuronide of the anti-inflammatory agent ML-3000 (HY-B1452), synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. D-Glucuronic acid lactone is promising for research of reversible cerebral vasoconstriction syndrome (RCVS) .
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- HY-N6612A
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- HY-N6612R
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- HY-N6612
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- HY-N7700A
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- HY-N6740
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- HY-125954
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UDP-α-D-Glucuronic acid
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Human Gut Microbiota Metabolites
Microorganisms
Source classification
Endogenous metabolite
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Endogenous Metabolite
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Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
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- HY-125954A
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- HY-N9412
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- HY-41982R
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- HY-128747A
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- HY-128747
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- HY-128749
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- HY-N9522
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- HY-N11976
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- HY-128749A
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- HY-W041019
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- HY-128749AR
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Calcium D-glucarate tetrahydrate (Standard)
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Structural Classification
Natural Products
Source classification
Endogenous metabolite
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Endogenous Metabolite
Reference Standards
Apoptosis
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D-Glucaric acid tetrahydrate (Standard) (Calcium D-glucarate tetrahydrate (Standard)) is the analytical standard of D-Glucaric acid tetrahydrate (HY-128749A). This product is intended for research and analytical applications. D-Glucaric acid tetrahydrate (Calcium D-glucarate tetrahydrate) is an orally active end product of the D-glucuronic acid pathway in mammals. D-Glucaric acid tetrahydrate is present in a variety of fruits and vegetables. D-Glucaric acid tetrahydrate has cholesterol-lowering and anti-tumor activities. D-Glucaric acid tetrahydrate can inhibit tumor cell proliferation and inflammation, and induce apoptosis .
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Product Name |
Chemical Structure |
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- HY-N6740S
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β-Zearalanol-d4 is a deuterium labeled Beta-Zearalanol (HY-N6740） . Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .
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- HY-N6612S
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D-Glucuronic acid sodium monohydrate- 13C6 is the 13C-labeled D-Glucuronic acid sodium salt monohydrate (HY-N6612A). D-Glucuronic acid sodium salt monohydrate is an endogenous metabolite.
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- HY-125954S
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Uridine diphosphate glucuronic acid- 13C, 15N2 (UDP-α-D-glucuronic acid- 13C, 15N2) is the 13C- and 15N-labeled Uridine diphosphate glucuronic acid (HY-125954). Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
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- HY-W008125S
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Acetobromo-a-D-glucuronic acid- 13C6 methyl ester (Methyl acetobromo-α-D-glucuronate- 13C6 methyl ester) is 13C labeled Acetobromo-α-D-glucuronic acid methyl ester, 98%. Acetobromo-α-D-glucuronic acid methyl ester, 98% (Acetobromo-alpha-D-glucuronic acid methyl ester, 98%) can be used in glycobiology research and can undergo glycosylation reactions with suitable glycoside receptors.
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- HY-W714797
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Nintedanib demethyl-O-glucuronic acid-d3 is the deuterium labeled (2R,3R,4R,5S,6S)-3,4,5-Trihydroxy-6-(((Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carbonyl)oxy)tetrahydro-2H-pyran-2-carboxylic acid (HY-W712456).
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- HY-W752886
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Estradiol 3-d3 (β-D-Glucuronide) sodium is the deuterium labeled Estradiol 3-(β-D-Glucuronide) sodium (HY-N7755). Estradiol 3-(β-D-Glucuronide) sodium is the glucuronic acid derivative of estradiol (HY-B0141). Estradiol 3-(β-D-Glucuronide) sodium is radiolabeled for use in tumor imaging and biodistribution studies .
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![β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)-βD-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene28-oate](http://file.medchemexpress.eu/product_pic/hy-n9522.gif)
