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Ophthalmic acid

" in MedChemExpress (MCE) Product Catalog:

38

Inhibitors & Agonists

4

Fluorescent Dye

1

Peptides

4

Natural
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2

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126752
    Ophthalmic acid

    		Reactive Oxygen Species Inflammation/Immunology
    Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction .
    Ophthalmic acid
  • HY-135808
    BIZ 114

    		NF-κB Inflammation/Immunology
    BIZ 114 (Example 11) is a fatty acid derivative and potent inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and / or treat ophthalmic disorders such as retinal degenerative disorders and ocular inflammatory diseases .
    BIZ 114
  • HY-W010892
    Scopolamine hydrobromide trihydrate
    10+ Cited Publications

    Hyoscine hydrobromide trihydrate

    		 mAChR Neurological Disease
    Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness .
    Scopolamine hydrobromide trihydrate
  • HY-133026
    N-Acetylcarnosine

    N-Acetyl-L-carnosine

    		 Drug Intermediate Endogenous Metabolite Inflammation/Immunology
    N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human cataracts .
    N-Acetylcarnosine
  • HY-127032
    Polyquaternium-1

    Polidronium chloride; PQ-1

    		 Biochemical Assay Reagents Infection
    Polyquaternium-1 (Polidronium chloride) is a polycationic ophthalmic preservative. Polyquaternium-1 can inhibit growth of microbial contaminants in multi-dose bottles of topical medications .
    Polyquaternium-1
  • HY-D0711
    Indocyanine green
    25+ Cited Publications

    Foxgreen; IC Green; Cardiogreen

    		 Fluorescent Dye Others
    Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
    Indocyanine green
  • HY-137431A
    (R)-Asundexian

    (R)-BAY-2433334

    		 TNF Receptor Drug Isomer Cardiovascular Disease
    (R)-Asundexian ((R)-BAY-2433334) is the enantiomer of Asundexian (HY-137431). (R)-Asundexian can be used in studies of cardiovascular disease (especially thrombotic or thromboembolic disease), edema, and ophthalmic disease .
    (R)-Asundexian
  • HY-139420
    Tafluprost ethyl amide

    		Prostaglandin Receptor Others
    Tafluprost ethyl amide is a prostaglandin derivative. Tafluprost ethyl amide is capable of intraocular pressure (IOP) reduction and influencing eyelash growth. Tafluprost ethyl amide can be used in antiglaucoma ophthalmic compositions or cosmetics .
    Tafluprost ethyl amide
  • HY-B1754
    Rimexolone

    Org 6216; Rimexel

    		 Glucocorticoid Receptor Inflammation/Immunology
    Rimexolone (Org 6216) is a glucocorticoid steroid with anti-inflammatory activity. Rimexolone can be used as a 1% ophthalmic suspension for the management of ocular inflammation .
    Rimexolone
  • HY-168904
    BI-1942

    		Proteasome Others
    BI-1942 is a chymase inhibitor and has an IC50 of 0.4 nM for human chymase. BI-1942 can be used in the research of ophthalmic diseases .
    BI-1942
  • HY-19518
    Latanoprostene bunod

    NCX116; LBN

    		 Prostaglandin Receptor Cardiovascular Disease Neurological Disease Cancer
    Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostaglandin F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT) .
    Latanoprostene bunod
  • HY-12720B
    Apraclonidine dihydrochloride

    ALO 2145 dihydrochloride

    		 Adrenergic Receptor Neurological Disease
    Apraclonidine (ALO 2145) dihydrochloride, a selective α2 and weak α1 receptor agonist activity, effectively low intraocular pressure (IOP) in eyes. Apraclonidine dihydrochloride is a topical ophthalmic solution .
    Apraclonidine dihydrochloride
  • HY-12720
    Apraclonidine

    ALO 2145 free base

    		 Adrenergic Receptor Infection Neurological Disease
    Apraclonidine (ALO 2145 (free base)), a selective α2 and weak α1 receptor agonist activity, effectively low intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution .
    Apraclonidine
  • HY-W010892R
    Scopolamine (hydrobromide trihydrate) (Standard)

    		mAChR Neurological Disease
    Scopolamine (hydrobromide trihydrate) (Standard) is the analytical standard of Scopolamine (hydrobromide trihydrate). This product is intended for research and analytical applications. Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness .
    Scopolamine (hydrobromide trihydrate) (Standard)
  • HY-W010066R
    4-(1,2-Dihydroxyethyl)benzene-1,2-diol (Standard)

    		Endogenous Metabolite Metabolic Disease
    Scopolamine (hydrobromide trihydrate) (Standard) is the analytical standard of Scopolamine (hydrobromide trihydrate). This product is intended for research and analytical applications. Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness .
    4-(1,2-Dihydroxyethyl)benzene-1,2-diol (Standard)
  • HY-12720A
    Apraclonidine hydrochloride
    2 Publications Verification

    ALO 2145

    		 Adrenergic Receptor Neurological Disease
    Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid .
    Apraclonidine hydrochloride
  • HY-164068
    Cross-linked sodium hyaluronate gel

    		Biochemical Assay Reagents Others Inflammation/Immunology
    Cross-linked sodium hyaluronate gel is a biomaterial formed by cross-linking sodium hyaluronate. Cross-linked sodium hyaluronate gel has good moisturizing properties, viscoelasticity and biocompatibility. Cross-linked sodium hyaluronate gel can be used for the treatment of arthritis and the development of auxiliary materials in ophthalmic surgery .
    Cross-linked sodium hyaluronate gel
  • HY-112076
    Atropine methyl bromide

    Methylatropine bromide

    		 mAChR Neurological Disease
    Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
    Atropine methyl bromide
  • HY-112076A
    Atropine methyl nitrate

    Methylatropine nitrate; Atropine methyl nitrate

    		 mAChR Neurological Disease
    Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
    Atropine methyl nitrate
  • HY-D0711R
    Indocyanine green (Standard)

    		Fluorescent Dye Others
    Indocyanine green (Standard) is the analytical standard of Indocyanine green. This product is intended for research and analytical applications. Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
    Indocyanine green (Standard)
  • HY-19518R
    Latanoprostene bunod (Standard)

    		Prostaglandin Receptor Neurological Disease
    Latanoprostene bunod (Standard) is the analytical standard of Latanoprostene bunod. This product is intended for research and analytical applications. Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostaglandin F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT) .
    Latanoprostene bunod (Standard)
  • HY-139420R
    Tafluprost ethyl amide (Standard)

    		Prostaglandin Receptor Others
    Tafluprost ethyl amide (Standard) is the analytical standard of Tafluprost ethyl amide. This product is intended for research and analytical applications. Tafluprost ethyl amide is a prostaglandin derivative. Tafluprost ethyl amide is capable of intraocular pressure (IOP) reduction and influencing eyelash growth. Tafluprost ethyl amide can be used in antiglaucoma ophthalmic compositions or cosmetics .
    Tafluprost ethyl amide (Standard)
  • HY-D0711S2
    Indocyanine green-d7

    Foxgreen-d7; IC Green-d7; Cardiogreen-d7

    		 Isotope-Labeled Compounds Fluorescent Dye Others
    Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
    Indocyanine green-d7
  • HY-12720AR
    Apraclonidine (hydrochloride) (Standard)

    		Adrenergic Receptor Neurological Disease
    Apraclonidine (hydrochloride) (Standard) is the analytical standard of Apraclonidine (hydrochloride). This product is intended for research and analytical applications. Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid .
    Apraclonidine (hydrochloride) (Standard)
  • HY-B0553
    Methazolamide
    2 Publications Verification

    L584601

    		 Carbonic Anhydrase Apoptosis Reactive Oxygen Species Caspase Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    Methazolamide (L584601) is a BBB-penatrable and orally active carbonic anhydrase inhibitor, with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide can reduce intraocular pressure and has a neuroprotective effect, being able to inhibit neuronal apoptosis. Methazolamide can be used in the research of ophthalmic diseases such as glaucoma and cerebrovascular diseases such as subarachnoid hemorrhage .
    Methazolamide
  • HY-100543
    Zenidolol

    ICI-118551

    		 Adrenergic Receptor Inflammation/Immunology
    Zenidolol (ICI-118551) is a selective β2 adrenergic receptor antagonist. Zenidolol inhibits β2-, β1- and β3-adrenergic receptor with Ki values of 0.7, 49.5 and 611 nM, respectively. Zenidolol can be used as an ocular hypotensive agent used for ophthalmic disease research .
    Zenidolol
  • HY-159702
    Eudragit RS 100

    		Mucin Others
    Eudragit RS 100 is a mucoadhesive, nonbiodegradable positively charged polymer,which can be used for research of developing nanoparticles (NPs) for the ophthalmic and oral administration of Ibuprofen (HY-78131) and Cyclosporins (HY-100731), as well as nano- and micro-fibres used as scaffolds. Eudragit RS 100 NPs interacts efficiently with mucin and promotes glutathione (GSH) transmucosal absorption .
    Eudragit RS 100
  • HY-112076R
    Atropine methyl (bromide) (Standard)

    		mAChR Neurological Disease
    Atropine methyl (bromide) (Standard) is the analytical standard of Atropine methyl (bromide). This product is intended for research and analytical applications. Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
    Atropine methyl (bromide) (Standard)
  • HY-B0553R
    Methazolamide (Standard)

    		Carbonic Anhydrase Apoptosis Reactive Oxygen Species Caspase Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    Methazolamide (Standard) is the analytical standard of Methazolamide. This product is intended for research and analytical applications. Methazolamide (L584601) is a BBB-penatrable and orally active carbonic anhydrase inhibitor, with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide can reduce intraocular pressure and has a neuroprotective effect, being able to inhibit neuronal apoptosis. Methazolamide can be used in the research of ophthalmic diseases such as glaucoma and cerebrovascular diseases such as subarachnoid hemorrhage .
    Methazolamide (Standard)
  • HY-B0580
    Ketorolac
    2 Publications Verification

    RS37619

    		 COX Apoptosis Inflammation/Immunology Cancer
    Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research .
    Ketorolac
  • HY-B0580D
    Ketorolac hydrochloride

    RS37619 hydrochloride

    		 COX Apoptosis Inflammation/Immunology Cancer
    Ketorolac (RS37619) hydrochloride is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac hydrochloride tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac hydrochloride tromethamine is also a DDX3 inhibitor that can be used for cancer research .
    Ketorolac hydrochloride
  • HY-B0580C
    Ketorolac hemicalcium

    RS37619 hemicalcium

    		 COX Apoptosis Inflammation/Immunology Cancer
    Ketorolac (RS37619) hemicalcium is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorola chemicalcium is also a DDX3 inhibitor that can be used for cancer research .
    Ketorolac hemicalcium
  • HY-126395
    Patent Blue V calcium salt

    		Fluorescent Dye Others
    Patent Blue V calcium salt is a triarylmethane dye used for tissue staining and lymphatic tracing, mainly applied by topical injection or eye drops. Patent Blue V calcium salt has affinity for specific tissues (such as corneal endothelium, lymphatic system), and stains the target structure by adsorption or binding, assisting in precise operation during surgery. Patent Blue V calcium salt is mainly used in ophthalmic surgery (such as graft staining for Descemet's membrane endothelial keratoplasty) and lymphatic drainage localization for sentinel lymph node biopsy of tumors .
    Patent Blue V calcium salt
  • HY-D0214R
    Rose Bengal (sodium) (Standard)

    		Influenza Virus Others
    Rose Bengal (sodium) (Standard) is the analytical standard of Rose Bengal (sodium). This product is intended for research and analytical applications. Rose Bengal sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities .
    Rose Bengal (sodium) (Standard)
  • HY-B0580R
    Ketorolac (Standard)

    		COX Apoptosis Inflammation/Immunology Cancer
    Ketorolac (Standard) is the analytical standard of Ketorolac. This product is intended for research and analytical applications. Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research .
    Ketorolac (Standard)
  • HY-B0580S2
    Ketorolac-13C6

    RS37619-13C6

    		 Isotope-Labeled Compounds Apoptosis COX Inflammation/Immunology Cancer
    Ketorolac- 13C6 (RS37619- 13C6) is 13C labeled Ketorolac. Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research .
    Ketorolac-13C6
  • HY-D0214
    Rose Bengal sodium
    1 Publications Verification

    		 Influenza Virus Photosensitizer Amyloid-β Infection Neurological Disease Cancer
    Rose Bengal sodium, a synthetic fluorescein derivative, is a deep red dye primarily composed of 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. It is widely used as an ophthalmic diagnostic agent to detect dry or damaged cells on the ocular surface. Rose Bengal sodium exhibits antitumor activity and can inhibit Friend Leukemia Virus (FLV) infection through photodynamic action. Additionally, Rose Bengal sodium can inhibit Aβ aggregation through light irradiation. Rose Bengal sodium holds potential for use in cancer, viral infections, and neurodegenerative disease research .
    Rose Bengal sodium
  • HY-16387
    PF 00337210

    		VEGFR Others
    PF-00337210 is a potent and selective inhibitor of VEGFRs, designed for treating age-related macular degeneration via intravitreal injection. The formulation strategy focused on developing an ophthalmic solution that would precipitate upon injection into the vitreous, ensuring sustained drug delivery. Challenges included maintaining low dosing volumes, selecting safe excipients for intravitreal use, and addressing the drug's unique physicochemical properties. The final formulation, an isotonic solution in a citrate-buffered vehicle with NaCl, demonstrated stability, potency, and recovery through intravitreal dosing syringes. It formed a depot upon injection into vitreous humor, representing a novel nonpolymeric in situ-forming depot formulation for intravitreal drug delivery .
    PF 00337210