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SGC7901

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Akt (1) Apoptosis (12) Autophagy (2) Bacterial (2) c-Met/HGFR (1) Endogenous Metabolite (1) ERK (2) Estrogen Receptor/ERR (2) Isotope-Labeled Compounds (1) Microtubule/Tubulin (3) NF-κB (1) NO Synthase (1) Reverse Transcriptase (2) STAT (1) Toll-like Receptor (TLR) (2) YAP (1)
By Research Areas:	Cancer (23) Endocrinology (2) Infection (2) Inflammation/Immunology (5)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W015084A

(E)-β-Ionone β-Lonone	Apoptosis	Cancer
(E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .

HY-W015084

β-Ionone	Apoptosis	Cancer
β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-N7980

Rubipodanone A	NF-κB	Cancer
Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB .

HY-155360

MY-1076	YAP Apoptosis	Cancer
MY-1076 is an inhibitor of YAP. MY-1076 induces YAP degradation and cell apoptosis. MY-1076 inhibits MGC-803, SGC-7901, HCT-116 and KYSE450 cells proliferation with IC₅₀ s of 0.019, 0.017, 0.020 and 0.044 μM, respectively .

HY-N10201

Cytoglobosin C	Endogenous Metabolite	Cancer
Cytoglobosin C, a cytochalasan derivative, shows potent cytotoxicity against both SGC-7901 and A549 cell lines (IC₅₀<10 μM) .

HY-W015084AR

(E)-β-Ionone (Standard)	Apoptosis	Cancer
(E)-β-Ionone (Standard) is the analytical standard of (E)-β-Ionone. This product is intended for research and analytical applications. (E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .

HY-N1841

Rocaglamide D 3'-Hydroxyrocaglamide	Others	Cancer
Rocaglamide D (3'-Hydroxyrocaglamide) (compound 1) is a lignan that can be found in Aglaia odorata. Rocaglamide D shows cytotoxicity with IC₅₀s of 0.32, 0.12, 0.25 µM for HeLa, SGC-7901, A549 cells, respectively .

HY-161351

STAT3/AKT-IN-1	Akt STAT Apoptosis	Cancer
STAT3/AKT-IN-1 is a dual inhibitor for the signal transducer and activator of transcription 3 (STAT3) and protein kinase B (AKT) signalling pathway, exhibits antitumor activity against gastric cancer and induces cell apoptosis in SGC-7901 cells .

HY-N9046

Citroside A	NO Synthase	Inflammation/Immunology Cancer
Citroside A is a megastigmane sesquiterpenoid with cytotoxic and anti-inflammatory activities. Citroside A displays potential effects against NO production with an IC₅₀ of 34.25 μM. Citroside A exhibits pronounced cytotoxicity against SGC-7901 and HeLa cells with IC₅₀ values of 27.52 μM and 29.51 μM, respectively .

HY-156098

c-Met-IN-19	c-Met/HGFR	Cancer
c-Met-IN-19 (Compound 21j) is a c-Met inhibitor (IC₅₀: 1.99 nM). c-Met-IN-19 shows cytotoxicity against A549, HT-29, SGC-7901, MDA-MB-231 cells with IC₅₀s of 0.25, 0.36, 0.98, 0.76 μM .

HY-W015084S

β-Ionone-13C3	Isotope-Labeled Compounds Apoptosis	Cancer
β-Ionone- ¹³C₃ is the ¹³C-labeled β-Ionone. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity[1].

HY-W015084R

β-Ionone (Standard)	Apoptosis	Cancer
β-Ionone (Standard) is the analytical standard of β-Ionone. This product is intended for research and analytical applications. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-146311

Tubulin polymerization-IN-16	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC₅₀ values of 0.084-0.221 μM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells .

HY-N13136

Timosaponin D	Others	Cancer
Timosaponin D, a natural steroid saponin, can be obtained from the rhizome of Anemarrhena asphodeloides. The IC₅₀ values of Timosaponin D against HepG2 and SGC7901 cells are 43.90 and 57.90 μM, respectively. Timosaponin D can be used in anticancer research .

HY-147947

Tubulin polymerization-IN-30	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-30 (compound 6e) is a potent Tubulin polymerization inhibitor. Tubulin polymerization-IN-30 is a colchicine binding site inhibitor. Tubulin polymerization-IN-30 can disrupt intracellular microtubule organization, arrest cell cycle at the G2/M phase. Tubulin polymerization-IN-30 exhibits the high potency against the cancer cell lines including SGC-7901, A549 and HeLa, with IC₅₀ values of 2.16, 2.21, and 0.403 μM .

HY-168102

Antiproliferative agent-59	Microtubule/Tubulin Apoptosis	Cancer
Antiproliferative agent-59 (Compound 14u) is an inhibitor for tubulin polymerization. Antiproliferative agent-59 exhibits antiproliferative activities against cancer cells Huh7, SGC-7901, and MCF-7 with IC₅₀ of 0.03, 0.18, and 0.13μM. Antiproliferative agent-59 arrests the cell cycle at G2/M phase and induces apoptosis in Huh7 cell. Antiproliferative agent-59 exhibits antitumor efficacy against liver cancer in Huh7 xenograft mouse models, without significant toxicity .

HY-B1100

Estradiol cypionate Maximum Cited Publications 9 Publications Verification	Estrogen Receptor/ERR Apoptosis	Endocrinology Cancer
Estradiol cypionate is the 17β-cypionate ester of Estradiol, which inhibits ET-1 synthesis by acting on estrogen receptors .

HY-B1100R

Estradiol cypionate (Standard)	Estrogen Receptor/ERR Apoptosis	Endocrinology Cancer
Estradiol cypionate (Standard) is the analytical standard of Estradiol cypionate. This product is intended for research and analytical applications. Estradiol cypionate is the 17β-cypionate ester of Estradiol, which inhibits ET-1 synthesis by acting on estrogen receptors .

HY-B1037

Salbutamol 4 Publications Verification Albuterol; AH-3365	Adrenergic Receptor ERK	Inflammation/Immunology Cancer
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) .

HY-B1037B

Salbutamol adipate Albuterol adipate; AH-3365 adipate	Adrenergic Receptor ERK	Inflammation/Immunology Cancer
Salbutamol (Albuterol) adipate is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol adipate promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol adipate is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) .

HY-133223

Hispidanin B	Others	Cancer
Hispidanin B is a natural product that can be extracted from the rhizomes of Isodon hispida. Hispidanin B has cytotoxic activities against cancer cells .

HY-N0462

Corilagin 4 Publications Verification	Toll-like Receptor (TLR) Reverse Transcriptase Bacterial Apoptosis Autophagy	Infection Inflammation/Immunology Cancer
Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .

HY-N0462R

Corilagin (Standard)	Toll-like Receptor (TLR) Reverse Transcriptase Bacterial Apoptosis Autophagy	Infection Inflammation/Immunology Cancer
Corilagin (Standard) is the analytical standard of Corilagin. This product is intended for research and analytical applications. Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015084A

(E)-β-Ionone β-Lonone	Structural Classification Viola odorata Linn. Terpenoids Sesquiterpenes Source classification Violaceae Plants	Apoptosis
(E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .

HY-W015084

β-Ionone	Structural Classification Classification of Application Fields Viola odorata Linn. Ketones, Aldehydes, Acids Source classification Violaceae Plants Disease Research Fields Cancer	Apoptosis
β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-N7980

Rubipodanone A	Quinones Structural Classification Classification of Application Fields Rubia podantha Source classification Rubiaceae Plants Naphthalene Quinones Disease Research Fields Cancer	NF-κB
Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB .

HY-B1100

Estradiol cypionate 5+ Cited Publications	Classification of Application Fields Disease Research Fields Cancer	Estrogen Receptor/ERR Apoptosis
Estradiol cypionate is the 17β-cypionate ester of Estradiol, which inhibits ET-1 synthesis by acting on estrogen receptors .

HY-N10201

Cytoglobosin C	Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids Cancer	Endogenous Metabolite
Cytoglobosin C, a cytochalasan derivative, shows potent cytotoxicity against both SGC-7901 and A549 cell lines (IC₅₀<10 μM) .

HY-W015084AR

(E)-β-Ionone (Standard)	Structural Classification Microorganisms Viola odorata Linn. Terpenoids Sesquiterpenes Source classification Violaceae Plants	Apoptosis
(E)-β-Ionone (Standard) is the analytical standard of (E)-β-Ionone. This product is intended for research and analytical applications. (E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .

HY-N1841

Rocaglamide D 3'-Hydroxyrocaglamide	Structural Classification Source classification Lignans Aglaia odorata Lour. Phenylpropanoids Plants Meliaceae	Others
Rocaglamide D (3'-Hydroxyrocaglamide) (compound 1) is a lignan that can be found in Aglaia odorata. Rocaglamide D shows cytotoxicity with IC₅₀s of 0.32, 0.12, 0.25 µM for HeLa, SGC-7901, A549 cells, respectively .

HY-N9046

Citroside A	Structural Classification Natural Products Source classification Hydrangeaceae Plants	NO Synthase
Citroside A is a megastigmane sesquiterpenoid with cytotoxic and anti-inflammatory activities. Citroside A displays potential effects against NO production with an IC₅₀ of 34.25 μM. Citroside A exhibits pronounced cytotoxicity against SGC-7901 and HeLa cells with IC₅₀ values of 27.52 μM and 29.51 μM, respectively .

HY-W015084R

β-Ionone (Standard)	Structural Classification Viola odorata Linn. Ketones, Aldehydes, Acids Source classification Violaceae Plants	Apoptosis
β-Ionone (Standard) is the analytical standard of β-Ionone. This product is intended for research and analytical applications. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-N13136

Timosaponin D	Triterpenes Structural Classification Liliaceae Terpenoids Source classification Anemarrhena asphodeloides Bunge Plants	Others
Timosaponin D, a natural steroid saponin, can be obtained from the rhizome of Anemarrhena asphodeloides. The IC₅₀ values of Timosaponin D against HepG2 and SGC7901 cells are 43.90 and 57.90 μM, respectively. Timosaponin D can be used in anticancer research .

HY-133223

Hispidanin B	Structural Classification Isodon hispidus (Bentham) Murata Terpenoids Labiatae Source classification Diterpenoids Plants	Others
Hispidanin B is a natural product that can be extracted from the rhizomes of Isodon hispida. Hispidanin B has cytotoxic activities against cancer cells .

HY-N0462

Corilagin 4 Publications Verification	Phyllanthus urinaria Linn. Infection Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Euphorbiaceae Plants Inflammation/Immunology Disease Research Fields	Toll-like Receptor (TLR) Reverse Transcriptase Bacterial Apoptosis Autophagy
Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .

HY-N0462R

Corilagin (Standard)	Phyllanthus urinaria Linn. Structural Classification Source classification Phenols Polyphenols Euphorbiaceae Plants	Toll-like Receptor (TLR) Reverse Transcriptase Bacterial Apoptosis Autophagy
Corilagin (Standard) is the analytical standard of Corilagin. This product is intended for research and analytical applications. Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .

Cat. No.	Product Name	Chemical Structure

HY-W015084S

β-Ionone-13C3
β-Ionone- ¹³C₃ is the ¹³C-labeled β-Ionone. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity[1].

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SGC7901

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products