Serratia

By Targets:	Antibiotic (7) Bacterial (8) Biochemical Assay Reagents (1) Parasite (4) Toll-like Receptor (TLR) (1)
By Research Areas:	Infection (9) Inflammation/Immunology (3) Metabolic Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131160

*Nuclease, Serratia* marcescens** Serratia marcescens nuclease	Biochemical Assay Reagents	Inflammation/Immunology
Serratia marcescens nuclease (EC 3.1.30.2) is a nonspecific nuclease. Serratia marcescens nuclease has broad utility due to its potent digestive activity toward both DNA and RNA .

HY-P2797

*Chitinase, Serratia* marcescens** AMCase, Serratia marcescens	Bacterial	Metabolic Disease Inflammation/Immunology
Chitinase, Serratia marcescens (EC 3.2.1.14) has partial lysozyme activity and is widely found in bacteria, fungi, animals and some plants. Chitinase belongs to the glycosyl hydrolase family. Chitinase catalyzes chito-oligosaccharide hydrolysis. Chitinases also can serve as prognostic biomarkers of disease progression. Chitinase can be used in the research of pathogenesis of various human fibrotic and inflammatory disorders, particularly those of the lung (idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, sarcoidosis, and asthma) and the gastrointestinal tract (inflammatory bowel diseases (IBDs) and colon cancer) .

HY-D1056H

Lipopolysaccharides, from S. marcescens LPS, from Serratia marcescens	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from S. marcescens, are lipopolysaccharide endotoxins that can activate pathogen-associated molecular patterns (PAMP) in the immune system and induce the secretion of exosomes by cells. Lipopolysaccharides can be extracted from the outer leaflet of the outer membrane of Gram-negative bacteria and consist of an O-specific antigen chain, a core oligosaccharide, and lipid A. Lipopolysaccharides, from S. marcescens, induce the activation of NF-κB in mouse cells through Toll-like receptor (TLR4)/MD-2. Lipopolysaccharides from S. marcescens can also induce apoptosis in host immune cellsS. marcescens .

HY-P2274

Argifin	Parasite	Infection
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-108307

Micronomicin sulfate Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate	Antibiotic Bacterial	Infection
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-B1118

Secnidazole RP-14539; PM-185184	Parasite Antibiotic Bacterial	Infection
Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .

HY-127054

Netilmicin Sch 20569	Antibiotic Bacterial	Infection
Netilmicin (Sch 20569) is an antibiotic. Netilmicin exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL .

HY-130066

Fortimicin C	Antibiotic Bacterial	Infection
Fortimicin C is an antibiotic, which can be isolated from Micromonospora olivoasterospora. Fortimicin C exhibits broad-spectrum antibacterial activity, inhibits Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhosa and Serratia marcescens, with MICs of 0.16-0.64 μg/mL. Fortimicin C is resistant against aminoglycoside inactivating enzymes .

HY-139698

GT-1 LCB10-0200	Others	Infection
GT-1 (LCB10-0200), a siderophore-linked cephalosporin, is effective against clinical isolates of P. aeruginosa, Klebsiella oxytoca, Proteus spp., Serratia marcescens, and Enterobacter aerogenes.

HY-B1118A

Secnidazole hemihydrate RP-14539 hemihydrate; PM-185184 hemihydrate	Antibiotic Bacterial Parasite	Infection
Secnidazole (RP-14539) hemihydrate is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole hemihydrate, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole hemihydrate has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole hemihydrate can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .

HY-B1118R

Secnidazole (Standard)	Parasite Antibiotic Bacterial	Infection
Secnidazole (Standard) is the analytical standard of Secnidazole. This product is intended for research and analytical applications. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .

HY-126735

Saquayamycin D	Antibiotic Bacterial	Infection
Saquayamycin D is an antibiotic, which can be isolated from Streptomyces nodosus culture broth. Saquayamycin D exhibits antibacterial activity against various gram-positive bacteria with MIC of 12.5-50 μg/mL. Saquayamycin D inhibits the proliferation of Doxorubicin (HY-15142)-sensitive P388/S and Doxorubicin-resistant P388/ADR with IC₅₀ of 0.15 and 0.15 μg/mL .

Cat. No.	Product Name	Type

HY-D1056H

Lipopolysaccharides, from S. marcescens LPS, from Serratia marcescens	Carbohydrates
Lipopolysaccharides, from S. marcescens, are lipopolysaccharide endotoxins that can activate pathogen-associated molecular patterns (PAMP) in the immune system and induce the secretion of exosomes by cells. Lipopolysaccharides can be extracted from the outer leaflet of the outer membrane of Gram-negative bacteria and consist of an O-specific antigen chain, a core oligosaccharide, and lipid A. Lipopolysaccharides, from S. marcescens, induce the activation of NF-κB in mouse cells through Toll-like receptor (TLR4)/MD-2. Lipopolysaccharides from S. marcescens can also induce apoptosis in host immune cellsS. marcescens .

Lipopolysaccharides, from S. marcescens

LPS, from Serratia marcescens

Carbohydrates

Lipopolysaccharides, from S. marcescens, are lipopolysaccharide endotoxins that can activate pathogen-associated molecular patterns (PAMP) in the immune system and induce the secretion of exosomes by cells. Lipopolysaccharides can be extracted from the outer leaflet of the outer membrane of Gram-negative bacteria and consist of an O-specific antigen chain, a core oligosaccharide, and lipid A. Lipopolysaccharides, from S. marcescens, induce the activation of NF-κB in mouse cells through Toll-like receptor (TLR4)/MD-2. Lipopolysaccharides from S. marcescens can also induce apoptosis in host immune cellsS. marcescens .

Cat. No.	Product Name	Target	Research Area

HY-P2274

Argifin	Parasite	Infection
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-108307

Micronomicin sulfate Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate	Infection Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-130066

Fortimicin C	Structural Classification Microorganisms Source classification Saccharides Monosaccharides	Antibiotic Bacterial
Fortimicin C is an antibiotic, which can be isolated from Micromonospora olivoasterospora. Fortimicin C exhibits broad-spectrum antibacterial activity, inhibits Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhosa and Serratia marcescens, with MICs of 0.16-0.64 μg/mL. Fortimicin C is resistant against aminoglycoside inactivating enzymes .

Tag:	His (1) Tag Free (1) Flag (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P702172

	*maiA Protein, Serratia* marcescens** maiA; Maleate isomerase; Maleate cis-trans isomerase	Others	E. coli
	The maiA protein is a key enzyme involved in catalyzing the cis-trans isomerization of the C2-C3 double bond in maleic acid, leading to the formation of fumaric acid. By facilitating this chemical transformation, maiA plays a crucial role in regulating the isomeric configuration of the C2-C3 double bond in maleic acid, ultimately converting it into fumaric acid. maiA Protein, Serratia marcescens is the recombinant maiA protein, expressed by E. coli , with tag free. The total length of maiA Protein, Serratia marcescens is 250 a.a., .

HY-P702173

	*maiA Protein, Serratia* marcescens (FLAG, His)** maiA; Maleate isomerase; Maleate cis-trans isomerase	Others	E. coli
	The maiA protein is a key enzyme involved in catalyzing the cis-trans isomerization of the C2-C3 double bond in maleic acid, leading to the formation of fumaric acid. By facilitating this chemical transformation, maiA plays a crucial role in regulating the isomeric configuration of the C2-C3 double bond in maleic acid, ultimately converting it into fumaric acid. maiA Protein, Serratia marcescens (FLAG, His) is the recombinant maiA protein, expressed by E. coli , with N-6*His, N-Flag labeled tag. The total length of maiA Protein, Serratia marcescens (FLAG, His) is 250 a.a., .

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Serratia

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