2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Lipopolysaccharides, from S. marcescens

Lipopolysaccharides, from S. marcescens  (Synonyms: LPS, from Serratia marcescens)

Cat. No.: HY-D1056H
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Lipopolysaccharides, from S. marcescens, are lipopolysaccharide endotoxins that can activate pathogen-associated molecular patterns (PAMP) in the immune system and induce the secretion of exosomes by cells. Lipopolysaccharides can be extracted from the outer leaflet of the outer membrane of Gram-negative bacteria and consist of an O-specific antigen chain, a core oligosaccharide, and lipid A. Lipopolysaccharides, from S. marcescens, induce the activation of NF-κB in mouse cells through Toll-like receptor (TLR4)/MD-2. Lipopolysaccharides from S. marcescens can also induce apoptosis in host immune cellsS. marcescens.

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Lipopolysaccharides, from S. marcescens Chemical Structure

Lipopolysaccharides, from S. marcescens Chemical Structure

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Lipopolysaccharides, from S. marcescens Related Antibodies

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Description

Lipopolysaccharides, from S. marcescens, are lipopolysaccharide endotoxins that can activate pathogen-associated molecular patterns (PAMP) in the immune system and induce the secretion of exosomes by cells. Lipopolysaccharides can be extracted from the outer leaflet of the outer membrane of Gram-negative bacteria and consist of an O-specific antigen chain, a core oligosaccharide, and lipid A. Lipopolysaccharides, from S. marcescens, induce the activation of NF-κB in mouse cells through Toll-like receptor (TLR4)/MD-2. Lipopolysaccharides from S. marcescens can also induce apoptosis in host immune cellsS. marcescens[1][2][3][4][5][6].

IC50 & Target

TLR-4[2]
Appearance

Solid

Color

White to off-white

SMILES

[Lipopolysaccharides, from S. marcescens]
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 5 mg/mL (Need ultrasonic and warming)

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Lipopolysaccharides, from S. marcescens Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lipopolysaccharides, from S. marcescensLPS, from Serratia marcescensToll-like Receptor (TLR)Inhibitorinhibitorinhibit

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