aromatic amino acids

By Targets:	Apoptosis (6) Autophagy (6) Carboxypeptidase (1) Endogenous Metabolite (1) Fluorescent Dye (2) Isotope-Labeled Compounds (3) Necroptosis (6) Neuropeptide Y Receptor (1) Ser/Thr Protease (4)
By Research Areas:	Cancer (1) Infection (2) Metabolic Disease (2) Neurological Disease (6)

Targets Recommended: Amino Acid Derivatives EAAT ELOVL Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0863

Glyphosate	Apoptosis Autophagy Necroptosis	Neurological Disease
Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .

HY-108910

Chymotrypsin 1 Publications Verification EC 3.4.21.1; Chymotrypsin A	Ser/Thr Protease	Others
Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids .

HY-D0017

Dansyl chloride DNSCl	Fluorescent Dye	Others
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .

HY-P1723

Spexin 1 Publications Verification Neuropeptide Q	Neuropeptide Y Receptor	Neurological Disease
Spexin is a conserved peptide plays roles of neurotransmitter/neuromodulator and endocrine factor. Spexin peptide contains numerous aromatic amino acids and is probably amidated .

HY-108910B

TLCK-treated Chymotrypsin	Ser/Thr Protease	Others
TLCK-treated Chymotrypsin is a serine protease. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids. TLCK treated to inactivate residual tryspin activity .

HY-P3150

Recombinant Proteinase K	Ser/Thr Protease	Others
Recombinant Proteinase K is a serine protease that cleaves the carboxy-terminated peptide bonds of aliphatic and aromatic amino acids. Recombinant Proteinase K can be used to digest proteins and remove contamination from nucleic acid preparations .

HY-B0863B

Glyphosate isopropylammonium	Apoptosis Autophagy Necroptosis	Neurological Disease
Glyphosate isopropylammonium, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate isopropylammonium inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate isopropylammonium induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .

HY-P2981

Carboxypeptidase C Carboxypeptidase Y; EC 3.4.16.1	Carboxypeptidase	Others
Carboxypeptidase C is a carboxypeptidase, is often used in biochemical studies. Carboxypeptidase C removes COOH-terminal lysine, arginine, and proline, as well as all other neutral, aliphatic, aromatic, and the acidic protein amino acids of a peptide chain .

HY-108910A

Chymotrypsin (MS grade) EC 3.4.21.1 (MS grade); Chymotrypsin A (MS grade)	Ser/Thr Protease	Others
Chymotrypsin (Chymotrypsin A) (MS grade) is a serine protease produced by the pancreas. Chymotrypsin (MS grade) cleaves protein chains at the carboxyl side of aromatic amino acids .

HY-147180

Dansyl-DL-valine cyclohexylammonium	Others	Others
Dansyl-DL-valine cyclohexylammonium is a salt form of Dansyl-DL-valine. Dansyl-DL-valine cyclohexylammonium can be used as analyte in chromatographic separation and separation column for the separation of enantiomers and diastereomers for dansyl amino acids, aromatic carboxylic acids, and isoxazolines .

HY-B0863S

Glyphosate-d2	Isotope-Labeled Compounds Apoptosis Autophagy Necroptosis	Neurological Disease
Glyphosate-d₂ is the deuterium labeled Glyphosate. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1].

HY-B0863R

Glyphosate (Standard)	Apoptosis Autophagy Necroptosis	Cancer
Glyphosate (Standard) is the analytical standard of Glyphosate. This product is intended for research and analytical applications. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .

HY-B0863S2

Glyphosate-d2-1	Isotope-Labeled Compounds Apoptosis Autophagy Necroptosis	Neurological Disease
Glyphosate-d₂-1 is the deuterium labeled Glyphosate[1]. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[2].

HY-B0863S3

Glyphosate-13C2,15N	Isotope-Labeled Compounds Apoptosis Autophagy Necroptosis	Neurological Disease
Glyphosate- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labled Glyphosate (HY-B0863). Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .

HY-113305

Dopamine 3-O-sulfate	Endogenous Metabolite	Metabolic Disease
Dopamine 3-O-sulfate mainly exists in plasma and can be used as a biomarker to characterize aromatic amino acid decarboxylase (AADC) deficiency .

HY-N3394

Lecanoric acid	Others	Infection
Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase .

HY-W141825

N-Acetyl-DL-phenylalanine β-naphthyl ester	Fluorescent Dye	Infection Metabolic Disease
N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .

Cat. No.	Product Name	Type

HY-D0017

Dansyl chloride DNSCl	Protein Labeling
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .

HY-W141825

N-Acetyl-DL-phenylalanine β-naphthyl ester	Chromogenic Substrates
N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .

Cat. No.	Product Name	Type

HY-N9934

(-)-3-Dehydroshikimic acid 3-DHS; 5-Dehydroshikimic acid	Biochemical Assay Reagents
(-)-3-Dehydroshikimic acid (3-DHS; 5-Dehydroshikimic acid) is an intermediate in the biosynthesis of aromatic amino acids. (-)-3-Dehydroshikimic acid shows antioxidant activity .

HY-108910

Chymotrypsin 1 Publications Verification EC 3.4.21.1; Chymotrypsin A	Biochemical Assay Reagents
Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids .

Cat. No.	Product Name	Target	Research Area

HY-P1723

Spexin 1 Publications Verification Neuropeptide Q	Neuropeptide Y Receptor	Neurological Disease
Spexin is a conserved peptide plays roles of neurotransmitter/neuromodulator and endocrine factor. Spexin peptide contains numerous aromatic amino acids and is probably amidated .

HY-P2787

Pro-Phe-Phe	Peptides	Others
Pro-Phe-Phe is the most aggregation-prone tripeptide of natural amino acids. Pro-Phe-Phe forms unique helical-like sheets that mate via aromatic dry interfaces. Pro-Phe-Phe can be used for the design of modular super-helical self-assembling nanostructures .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N9934

(-)-3-Dehydroshikimic acid 3-DHS; 5-Dehydroshikimic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
(-)-3-Dehydroshikimic acid (3-DHS; 5-Dehydroshikimic acid) is an intermediate in the biosynthesis of aromatic amino acids. (-)-3-Dehydroshikimic acid shows antioxidant activity .

HY-B0863

Glyphosate	Microorganisms Source classification	Apoptosis Autophagy Necroptosis
Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .

HY-N3394

Lecanoric acid	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Others
Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase .

HY-B0863R

Glyphosate (Standard)	Microorganisms Source classification	Apoptosis Autophagy Necroptosis
Glyphosate (Standard) is the analytical standard of Glyphosate. This product is intended for research and analytical applications. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .

HY-113305

Dopamine 3-O-sulfate	Structural Classification Natural Products Classification of Application Fields Animals Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Dopamine 3-O-sulfate mainly exists in plasma and can be used as a biomarker to characterize aromatic amino acid decarboxylase (AADC) deficiency .

Cat. No.	Product Name	Chemical Structure

HY-B0863S

Glyphosate-d2
Glyphosate-d₂ is the deuterium labeled Glyphosate. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1].

HY-B0863S2

Glyphosate-d2-1
Glyphosate-d₂-1 is the deuterium labeled Glyphosate[1]. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[2].

HY-B0863S3

Glyphosate-13C2,15N
Glyphosate- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labled Glyphosate (HY-B0863). Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .

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