Search Result
Results for "
by-product
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
8
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-76199
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Others
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Metabolic Disease
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trans-4-Hydroxycyclohexanecarboxylic acid is a substrate for cyclohexanecarboxylic acid production. trans-4-Hydroxycyclohexanecarboxylic acid is the by-product of intestinal bacterial metabolism via urinary excretion .
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- HY-133666
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Others
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Others
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Diiodoacetamide, a iodo-haloacetamide, is a disinfection by-product (DBP) in drinking water .
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- HY-133665
-
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Others
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Others
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2,2-Dibromoacetamide is a class of disinfection by-product (DBP) in drinking water .
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- HY-133646
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DNA/RNA Synthesis
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Others
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Bromochloroacetonitrile is a by-product of the chlorine disinfection of water containing natural organic material. Bromochloroacetonitrile possesses direct acting mutagenic activity and is capable of inducing DNA strand breakage .
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- HY-133643
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Others
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Others
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Bromodichloroacetonitrile is a nitrogen-containing disinfection byproduct .
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- HY-133644
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Others
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Others
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Tribromoacetonitrile is a nitrogen-containing disinfection byproduct .
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- HY-133647
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Others
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Others
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Dibromoacetaldehyde, a halogenated product, is a byproduct in drinking water and has genotoxicity .
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- HY-133659
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Others
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Others
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Diiodoacetic acid is a disinfection by-product (DBP) formed during water disinfection .
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- HY-133664
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Others
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Others
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Dibromochloroacetamide is one of haloacetamides, which are the drinking water disinfection byproducts (DBPs) .
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- HY-133648
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Others
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Others
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Bromochloroacetaldehyde belongs to dihalogenated acetaldehyde and is a byproduct in drinking water. Bromochloroacetaldehyde has genotoxicity .
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- HY-133649
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Others
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Others
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Dibromochloroacetaldehyde belongs to trihalogenated acetaldehyde and is a byproduct in drinking water. Dibromochloroacetaldehyde has genotoxicity .
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- HY-133657
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Others
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Others
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Bromoiodoacetic acid, one of iodinated haloacids, is a disinfection byproduct (DBP) at in finished drinking waters .
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- HY-131103
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- HY-113158
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Others
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Others
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4-Hydroxyhippuric acid is a by-product of metabolism of polyphenols and increases the microflora activity related to the refeeding .
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- HY-119326
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Others
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Neurological Disease
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N-Formylmethamphetamine is an impurity in the synthesis of methamphetamine. N-Formylmethamphetamine is also a by-product of the Nagai reaction .
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- HY-133631
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Others
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Others
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Chloronitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-133633
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Others
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Others
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Bromodichloronitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-133634
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Others
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Others
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Dibromochloronitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-133635
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Others
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Others
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Tribromonitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-133636
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Others
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Others
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Bromochloronitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-N0593
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- HY-N0593A
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- HY-N0593B
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- HY-23399
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Apoptosis
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Others
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Dibromoacetic acid, a haloacetic acid found in drinking water as a disinfection by-product, can cause many adverse effects, including immunotoxicity and apoptosis .
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- HY-133655
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Others
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Others
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(E)-2,3-Dibromo-2-butenedioic acid is one of brominated haloacids, which are the drinking water disinfection byproducts (DBPs) .
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- HY-W010451
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Calcium Channel
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Cardiovascular Disease
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1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca 2+ concentration in rat thymic lymphocytes .
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- HY-131103S
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- HY-133656
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cis-2-Bromo-3-methylbutenendioic acid
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Others
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Others
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(Z)-2-Bromo-3-methyl-2-butenedioic acid, one of brominated haloacids, is a disinfection byproduct (DBP) at in finished drinking waters .
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- HY-133629
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Others
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Others
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1,1,1,3-Tetrachloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
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- HY-133653
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3,3-Dibromoacrylic acid
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Others
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Others
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3,3-Dibromopropenoic acid is a 3,3-dibromo product based on propenoic acid. 3,3-Dibromopropenoic acid is a polar aromatic brominated disinfection byproduct during chlorination in water .
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- HY-W133982
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Biochemical Assay Reagents
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Infection
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Corn steep liquor, a food industrial by-product, is a nutritional additive in the liquid culture medium of fungus. Corn steep liquor can increase the production of fairy chemicals and mycelia .
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- HY-B1207
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Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane
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Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
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- HY-133625
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Others
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Others
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1,1-Dibromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
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- HY-133627
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Others
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Others
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1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
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- HY-133628
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Others
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Others
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1,1,3-Tribromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
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- HY-133626
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Others
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Others
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1,1-Dibromo-3,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
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- HY-113158R
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Others
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Others
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4-Hydroxyhippuric acid (Standard) is the analytical standard of 4-Hydroxyhippuric acid. This product is intended for research and analytical applications. 4-Hydroxyhippuric acid is a by-product of metabolism of polyphenols and increases the microflora activity related to the refeeding .
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- HY-121883
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Tetracosanoic acid
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Endogenous Metabolite
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Neurological Disease
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Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research .
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- HY-B1207S
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Ethyl carbamate-d5; Carbamic acid ethyl ester-d5; Ethylurethane-d5
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Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].
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- HY-133654
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Others
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Others
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2,3,3-Tribromopropenoic acid is a 2,3,3-Tribromo product based on propenoic acid. 2,3,3-Tribromopropenoic acid is a polar aromatic brominated disinfection byproduct during chlorination in water and shows cytotoxic potency in mammalian cell chronic cytotoxicity experiments .
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- HY-B1207R
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Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane (Standard) is the analytical standard of Urethane. This product is intended for research and analytical applications. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
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- HY-W010451R
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Calcium Channel
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Cardiovascular Disease
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1,2,4-Trihydroxybenzene (Standard) is the analytical standard of 1,2,4-Trihydroxybenzene. This product is intended for research and analytical applications. 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes .
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- HY-121883S
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Tetracosanoic acid-d47
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Isotope-Labeled Compounds
Endogenous Metabolite
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Neurological Disease
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Lignoceric acid-d47 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
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- HY-121883S3
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Endogenous Metabolite
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Neurological Disease
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Lignoceric acid-d4-11 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
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- HY-121883S4
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Tetracosanoic acid-d4-2
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Endogenous Metabolite
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Neurological Disease
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Lignoceric acid-d4-2 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
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- HY-121883SS5
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Endogenous Metabolite
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Neurological Disease
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Lignoceric acid-d9 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
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- HY-W010712
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Amino Acid Derivatives
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Others
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Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .
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- HY-E70310
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Lipase for biodiesel production
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Endogenous Metabolite
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Others
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BD-10X (Lipase for biodiesel production) is a methanol-resistant lipase with high catalytic activity and can be used for the production of biodiesel. The reaction conditions of BD-10X are mild, which can avoid the oxidation of hydroxyl groups and the opening of double bonds, and prevent the production of by-products other than glycerol .
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- HY-121883S1
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Tetracosanoic acid-d3
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Endogenous Metabolite
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Neurological Disease
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Lignoceric acid-d3 is the deuterium labeled Lignoceric acid[1]. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[2][3].
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- HY-162882
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Xanthine Oxidase
Reactive Oxygen Species
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Metabolic Disease
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CC15009 is a xanthine oxidoreductase (XOR) inhibitor, with an IC50 value of 0.237 nM. CC15009 can inhibit the oxidative subtype of XOR, thereby reducing the production of the byproduct ROS and exhibiting antioxidant activity. CC15009 has demonstrated a good dose-dependent uric acid-lowering effect in two different mouse models of hyperuricemia induced by XOR substrates .
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- HY-W543065
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Others
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CPhos Pd G2 is a highly efficient palladium catalyst with excellent cross-coupling reaction activity. CPhos Pd G2 is widely used in compound synthesis and material science, especially for the construction of complex organic molecules and the synthesis of bioactive compounds. CPhos Pd G2 is also favored for improving reaction selectivity and reducing the formation of by-products.
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- HY-126255
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NAMPT
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Metabolic Disease
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SBI-797812 is an orally active nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 shifts NAMPT to NMN formation, increases NAMPT affinity for ATP, stabilizes phosphorylated NAMPT, promotes consumption of the pyrophosphate by-product, and blunts feedback inhibition by NAD +. SBI-797812 increases intracellular nicotinamide mononucleotide (NMN) and elevates liver NAD + in mice .
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- HY-115706
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1,3-Ditetracosanoin
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Biochemical Assay Reagents
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Neurological Disease
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13-Dilignoceroyl glycerol is a diacylglycerol containing lignoceric acid (HY-121883 ) at the sn-1 and sn-3 positions. Lignoceric acid is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy research .
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- HY-W012088
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Myristoleic acid methyl ester; Methyl myristoleate; cis-9-Tetradecenoate methyl ester
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Others
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Infection
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(Z)-Methyl tetradec-9-enoate (Myristoleic acid methyl ester; Methyl myristoleate) is a cytotoxic component extracted from S. repens fruit extract. It induces apoptosis and necrosis in human prostate cancer LNCaP cells. In addition, (Z)-Methyl tetradec-9-enoate found in cheese-making byproducts inhibits Candida albicans germination with a minimum inhibitory concentration (MIC) of 9 μM in vivo.
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- HY-W010712S1
-
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Isotope-Labeled Compounds
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Others
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Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
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- HY-121178
-
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Others
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Infection
|
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Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein (HY-119809) that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 μM. Deoxyviolacein (125 μg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.
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- HY-117074
-
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Others
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Infection
|
|
BMS-247243 is a β-lactam antibiotic against methicillin-resistant Staphylococcus aureus. This section introduces its synthesis method and biological properties. A practical synthetic method was developed to exchange iodide ions with chloride ions to form 4-thiopyridinol 6b with C-3 side chain, thereby effectively synthesizing methyl ester 12b with C-7 side chain. The reaction of 14 with methylthiolate lithium salt was catalyzed by Bu4NCl to form methyl ester 12b in high yield. Reaction with thiolate dianion gave the corresponding Michael addition byproduct, resulting in a decrease in the quality of thermodynamic product 12b. The diester 17 was synthesized by acid chlorination acylation of 16 with 12b in a two-phase system, avoiding the troublesome deprotection work such as using DCC or EDAC. During the TFA reaction to remove the protecting group 17, the bis acid 20 was unexpectedly obtained. The bis acid 19 reacted with 4-thiopyridinol 6b to form BMS-247243 in moderate yield. Alternatively, efficient coupling of diester 17 with 4-thiopyridinol 6b afforded crystalline diester 21 with little contamination from isomer 22. Double deprotection of diester 21 followed by crystallization afforded the bis-zwitterion BMS-247243 in high yield.
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HY-L098
-
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231 compounds
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A drug metabolite is a byproduct of the body breaking down, or “metabolizing” a drug into a different substance. Most drugs undergo chemical alteration by various bodily systems as a way to create compounds that are more easily excreted from the body. Drugs can be metabolized by oxidation, reduction, hydrolysis, hydration, conjugation, condensation, or isomerization. Drug metabolism can produce metabolites with physicochemical and pharmacological properties that differ substantially from those of the parent drug, and consequently have important implications for both drug safety and efficacy.
MCE offers a unique collection of 231 drug metabolites which is a useful tool for drug safety and efficacy study and drug repurposing.
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| Cat. No. |
Product Name |
Type |
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- HY-W133982
-
|
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Microbial Culture
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|
Corn steep liquor, a food industrial by-product, is a nutritional additive in the liquid culture medium of fungus. Corn steep liquor can increase the production of fairy chemicals and mycelia .
|
| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-W010712
-
|
|
Amino Acid Derivatives
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Others
|
|
Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
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- HY-131103S
-
|
|
|
Phenylethanolamine A-d3 is a deuterium labeled Phenylethanolamine A. Phenylethanolamine A acts as a β-adrenergic agonist. Phenylethanolamine A is a byproduct during the Ractopamine synthesis process[1].
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- HY-B1207S
-
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Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].
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- HY-121883S
-
|
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Lignoceric acid-d47 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
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- HY-121883S3
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Lignoceric acid-d4-11 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
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- HY-121883S4
-
|
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Lignoceric acid-d4-2 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
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- HY-121883SS5
-
|
|
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Lignoceric acid-d9 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
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- HY-121883S1
-
|
|
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Lignoceric acid-d3 is the deuterium labeled Lignoceric acid[1]. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[2][3].
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- HY-W010712S1
-
|
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Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
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| Cat. No. |
Product Name |
|
Classification |
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- HY-N0593A
-
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Sodium deoxycholate
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Emulsifiers
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Deoxycholic acid sodium salt (sodium deoxycholate), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5 .
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