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Results for "

calcimimetic

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-109106A
    Upacicalcet sodium

    		CaSR Endocrinology
    Upacicalcet sodium is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) .
    Upacicalcet sodium
  • HY-109106B
    (Rac)-Upacicalcet

    		CaSR Endocrinology
    (Rac)-Upacicalcet is the racemate of Upacicalcet.Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) .
    (Rac)-Upacicalcet
  • HY-122819
    Calindol hydrochloride

    		CaSR Cardiovascular Disease
    Calindol hydrochloride is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM .
    Calindol hydrochloride
  • HY-10167A
    Tecalcet Hydrochloride
    Maximum Cited Publications
    6 Publications Verification

    R-568 hydrochloride; NPS R-568

    		 CaSR Others
    Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca 2+ .
    Tecalcet Hydrochloride
  • HY-P1955A
    Etelcalcetide hydrochloride
    2 Publications Verification

    Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride

    		 CaSR Endocrinology
    Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .
    Etelcalcetide hydrochloride
  • HY-109106
    Upacicalcet

    		CaSR Endocrinology
    Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) .
    Upacicalcet
  • HY-10167
    Tecalcet

    R-568; NPS R-568 free base

    		 CaSR Others
    Tecalcet (R 568), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet (R 568) increases the sensitivity to activation by extracellular Ca 2+ .
    Tecalcet
  • HY-P1955
    Etelcalcetide

    Velcalcetide; AMG 416; KAI-4169

    		 CaSR Metabolic Disease
    Etelcalcetide (AMG 416; KAI-4169) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .
    Etelcalcetide

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