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contraceptive

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40

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3

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8

Isotope-Labeled Compounds

10

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1830

    Estrogen Receptor/ERR Endocrinology
    Estradiol enanthate is a shorter-acting estrogen. The combination of Estradiol enanthate and dihydroxyprogesterone acetophenide can be used as a monthly injectable contraceptive .
    Estradiol enanthate
  • HY-B0487

    Pregneninolone; 17α-Ethynyltestosterone

    Estrogen Receptor/ERR Endocrinology
    Ethisterone (Pregneninolone), a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone is reported for androgenic activity, used for the research of the gynecological disorders .
    Ethisterone
  • HY-105634A

    Progesterone Receptor Endocrinology Cancer
    Nomegestrol acetate is an orally active, highly selective progestogen and a progesterone receptor complete agonist. Nomegestrol acetate inhibits ovulation. Nomegestrol acetate is also effective in inhibiting the proliferation of human endometrial cancer RL95-2 cells in vitro and in vivo. Nomegestrol acetate can be used in cancer (especially endometrial cancer) and contraceptive studies .
    Nomegestrol acetate
  • HY-162565

    STK33 CDK RET Endocrinology
    CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with IC50 of 9.2 nM. CDD-2807 exhibits no significant toxicity in mice and can cross the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of the male contraceptive .
    CDD-2807
  • HY-B1830R

    Estrogen Receptor/ERR Endocrinology
    Estradiol enanthate (Standard) is the analytical standard of Estradiol enanthate. This product is intended for research and analytical applications. Estradiol enanthate is a shorter-acting estrogen. The combination of Estradiol enanthate and dihydroxyprogesterone acetophenide can be used as a monthly injectable contraceptive .
    Estradiol enanthate (Standard)
  • HY-157250

    Apoptosis Endocrinology
    BHD is an effective, orally active and reversible contraceptive agent. BHD induces the apoptosis of spermatogenic cells rapidly and disruptes the blood-testis barrier effectively .
    BHD
  • HY-B0487R

    Estrogen Receptor/ERR Endocrinology
    Ethisterone (Standard) is the analytical standard of Ethisterone. This product is intended for research and analytical applications. Ethisterone (Pregneninolone), a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone is reported for androgenic activity, used for the research of the gynecological disorders .
    Ethisterone (Standard)
  • HY-116806

    CFTR Endocrinology
    AF-2785 is a potent CFTR blocker. AF-2785 inhibits the cAMP-activated chloride current in rat epididymal cells with an IC50 of 170.6 μM. AF-2785 can be used in research related to contraceptives .
    AF-2785
  • HY-123492

    Opioid Receptor Neurological Disease Endocrinology
    Kentsin, a contraceptive tetrapeptide, is originally extracted from hamster embryos. Kentsin prevents the maturation of Graafian follicles and consequently inhibits ovulation. Kentsin has opiate properties on gastrointestinal motility .
    Kentsin
  • HY-105634AR

    Progesterone Receptor Endocrinology Cancer
    Nomegestrol acetate (Standard) is the analytical standard of Nomegestrol acetate. This product is intended for research and analytical applications. Nomegestrol acetate is an orally active, highly selective progestogen and a progesterone receptor complete agonist. Nomegestrol acetate inhibits ovulation. Nomegestrol acetate is also effective in inhibiting the proliferation of human endometrial cancer RL95-2 cells in vitro and in vivo. Nomegestrol acetate can be used in cancer (especially endometrial cancer) and contraceptive studies .
    Nomegestrol acetate (Standard)
  • HY-W013172

    Progesterone Receptor Endocrinology
    Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive . Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate
  • HY-123035

    HSP Akt EGFR Endocrinology
    Gamendazole, an indazole carboxylic acid (ICA), is an orally active, selective HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A) inhibitor. Gamendazole binds to the C-terminal nucleotide binding pocket of HSP90 and cause downregulation of clients AKT1 and ERBB2, but stabilizes the HSP90 heterocomplex. Gamendazole specifically inhibits the actin bundling function of EEF1A1, but does not bind to the nucleotide docking pocket nor inhibits the ribosome charging or protein translation functions of EEF1A1. Gamendazole, an antispermatogenic compound with antifertility effects, has the potential for reversible non-hormonal male contraceptive agent research .
    Gamendazole
  • HY-B0110S

    SHB 331-d6; WL 70-d6

    Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Gestodene-d6is the deuterium labeled Gestodene. Gestodene(SHB 331) is a progestogen hormonal contraceptive[1][2]. Gestodene-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Gestodene-d6
  • HY-B0257S

    D-Norgestrel-d8

    Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Levonorgestrel-d8 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives[1][2]. Levonorgestrel-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Levonorgestrel-d8
  • HY-B1027

    Nonoxynol; Nonoxinol

    Biochemical Assay Reagents Others
    4-Nonylphenol polyethoxylate is an organic compound that is a nonionic surfactant; widely used in contraceptives for its spermicidal properties.
    4-Nonylphenol polyethoxylate
  • HY-18996
    Adjudin
    3 Publications Verification

    AF-2364

    Chloride Channel Mitochondrial Metabolism Cancer
    Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin is also a potent Cl - channel blocker.
    Adjudin
  • HY-133007

    Progesterone Receptor Metabolic Disease
    Algestone acetophenide is a progesterone drug. Algestone acetophenide can be used in combination with estrogen as a long-acting injectable contraceptive .
    Algestone acetophenide
  • HY-139244S

    Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Norgestimate-d6 is the deuterium labeled Norgestimate. Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2]. Norgestimate-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate-d6
  • HY-139741

    DNA/RNA Synthesis Others
    cyclo(Phe-Ala-Gly-Arg-Arg-Arg-Gly-AEEAc) provides an avenue for developing a nonhormonal male contraceptive by blocking of GRTH/DDX25 phosphorylation.
    cyclo(Phe-Ala-Gly-Arg-Arg-Arg-Gly-AEEAc)
  • HY-13071
    Nestoron
    1 Publications Verification

    ST-1435; Elcometrine

    Progesterone Receptor Endocrinology
    Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive .
    Nestoron
  • HY-133056R

    Antibiotic Bacterial Infection
    Algestone acetophenide (Standard) is the analytical standard of Algestone acetophenide. This product is intended for research and analytical applications. Algestone acetophenide is a progesterone drug. Algestone acetophenide can be used in combination with estrogen as a long-acting injectable contraceptive .
    Pseudomonic acid C (Standard)
  • HY-133007R

    Progesterone Receptor Metabolic Disease
    Algestone acetophenide (Standard) is the analytical standard of Algestone acetophenide. This product is intended for research and analytical applications. Algestone acetophenide is a progesterone drug. Algestone acetophenide can be used in combination with estrogen as a long-acting injectable contraceptive .
    Algestone acetophenide (Standard)
  • HY-132280R

    Antibiotic Infection Neurological Disease
    Estradiol enanthate (Standard) is the analytical standard of Estradiol enanthate. This product is intended for research and analytical applications. Estradiol enanthate is a shorter-acting estrogen. The combination of Estradiol enanthate and dihydroxyprogesterone acetophenide can be used as a monthly injectable contraceptive .
    Tirilazad (Standard)
  • HY-W013172R

    Progesterone Receptor Endocrinology
    Norgestimate (Standard) is the analytical standard of Norgestimate. This product is intended for research and analytical applications. Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive .
    Norgestimate (Standard)
  • HY-N7137R

    Reactive Oxygen Species Neurological Disease Cancer
    Norgestrel (Standard) is the analytical standard of Norgestrel. This product is intended for research and analytical applications. Norgestrel is a synthetic analog of progesterone, a compound commonly found in oral contraceptive pill, and a powerful neuroprotective antioxidant, preventing light-induced ROS in photoreceptor cells, and cell death .
    Norgestrel (Standard)
  • HY-B0257
    Levonorgestrel
    1 Publications Verification

    D-Norgestrel

    Apoptosis Caspase Bcl-2 Family Survivin Endocrinology Cancer
    Levonorgestrel is an orally active inhibitor of progesterone (HY-N0437). Levonorgestrel has anticancer activity and can induce Apoptosis. Levonorgestrel can be used as a contraceptive and in combination with other medications. Levonorgestrel can be used in the study of osteoporosis and uterine leiomyoma .
    Levonorgestrel
  • HY-12516
    Desogestrel
    1 Publications Verification

    Org-2969

    Progesterone Receptor Others
    Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    Desogestrel
  • HY-B0257S1

    Isotope-Labeled Compounds Progesterone Receptor Endocrinology
    Norgestrel-d6 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestrel-d6
  • HY-A0285

    Norigest

    Progesterone Receptor Endocrinology
    Norethisterone enanthate is a long-acting parenteral progestogen. Norethisterone enanthate is orally active . Norethisterone enanthate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norethisterone enanthate
  • HY-A0285R

    Progesterone Receptor Endocrinology
    Norethisterone enanthate (Standard) is the analytical standard of Norethisterone enanthate. This product is intended for research and analytical applications. Norethisterone enanthate is a long-acting parenteral progestogen. Norethisterone enanthate is orally active . Norethisterone enanthate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norethisterone enanthate (Standard)
  • HY-111614

    Progesterone Receptor Metabolic Disease Cancer
    Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity . Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research .
    Melengestrol acetate
  • HY-N7137

    Reactive Oxygen Species Neurological Disease Cancer
    Norgestrel is a synthetic analog of progesterone, a compound commonly found in oral contraceptive pill, and a powerful neuroprotective antioxidant, preventing light-induced ROS in photoreceptor cells, and cell death . Norgestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestrel
  • HY-111614S

    Progesterone Receptor Metabolic Disease Cancer
    Melengestrol acetate-d6 is the deuterium labeled Melengestrol acetate. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity[1]. Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research[2].
    Melengestrol acetate-d6
  • HY-111614S2

    Isotope-Labeled Compounds Progesterone Receptor Metabolic Disease Cancer
    Melengestrol acetate-d3 is the deuterium labeled Melengestrol acetate. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity[1]. Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research[2].
    Melengestrol acetate-d3
  • HY-164032

    7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate

    GnRH Receptor Endocrinology
    Dimethandrolone undecanoate (7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate) exhibits withrogens and progesterone activity. Dimethandrolone undecanoate inhibits production of gonadotropins, suppresses testosterone production, and thus inhibits sperm production. Dimethandrolone undecanoate is potent for development of male hormone contraceptives .
    Dimethandrolone undecanoate
  • HY-111614R

    Progesterone Receptor Metabolic Disease Cancer
    Melengestrol acetate (Standard) is the analytical standard of Melengestrol acetate. This product is intended for research and analytical applications. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity . Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research .
    Melengestrol acetate (Standard)
  • HY-111614S1

    Progesterone Receptor Metabolic Disease Cancer
    Melengestrol acetate-d2 is the deuterium labeled Melengestrol acetate. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity[1]. Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research[2].
    Melengestrol acetate-d2
  • HY-B0216S

    17α-Ethynylestradiol-d4; Ethynylestradiol-d4

    Estrogen Receptor/ERR Endogenous Metabolite Endocrinology Cancer
    Ethynyl Estradiol-d4 is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ethynyl Estradiol-d4
  • HY-P3664

    Wy 18185

    GnRH Receptor Endocrinology
    [D-Phe2,D-Ala6]-LH-RH is a potent LH-RH antagonist. [D-Phe2,D-Ala6]-LH-RH shows anti-LH/FSH-RH and antiovulatory activities .
    [D-Phe2,D-Ala6]-LH-RH
  • HY-164911

    Potassium Channel Endocrinology
    VU0546110 is a selective inhibitor of the sperm-specific potassium channel SLO3, with IC50s of 1.287 μM (SLO3) and 59.80 μM (SLO1) in HEK293 cells, respectively. VU0546110 blocks heterologous SLO3 currents and endogenous K + currents in human sperm. VU0546110 halts sperm hyperpolarization, induced acrosome reaction, and hyper-activated motility. VU0546110 has contraceptive potential .
    VU0546110

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