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coumarin compound

" in MedChemExpress (MCE) Product Catalog:

34

Inhibitors & Agonists

1

Screening Libraries

1

Fluorescent Dye

1

Biochemical Assay Reagents

21

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W027968
    Coumarin-3-carboxylic Acid
    2 Publications Verification

    2-Oxochromene-3-carboxylic acid

    Others Cancer
    Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line .
    Coumarin-3-carboxylic Acid
  • HY-109714

    Others Inflammation/Immunology
    3,4-Benzocoumarin is a kind of the expanded structure of coumarin derivatives.Coumarin is a chemical compound in the benzopyrone chemical class that can be found in many natural species. Coumarins possess variety of biological activities and unique photophysical properties . 3,4-Benzocoumarin, a AOH‐like compound , has the sensibility of the antibody with an IC50 of 919.2 ng/mL .
    3,4-Benzocoumarin
  • HY-N0573
    Umbelliferone
    2 Publications Verification

    7-Hydroxycoumarin; Hydrangin; NSC 19790

    Endogenous Metabolite Apoptosis Cancer
    Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.
    Umbelliferone
  • HY-N2623
    Alloimperatorin
    1 Publications Verification

    Prangenidin

    Others Cancer
    Alloimperatorin (Prangenidin), a coumarin compound, is extracted from Angelica dahurica. Alloimperatorin (Prangenidin) has antitumor activity .
    Alloimperatorin
  • HY-N8632

    Others Others
    Qianhucoumarin A is a natural coumarin compound found in the roots of Peucedanum praeruptorum Dunn .
    Qianhucoumarin A
  • HY-D0046

    2-Oxo-2H-chromene-6-sulfonyl chloride

    Biochemical Assay Reagents Others
    Coumarin-6-sulfonyl chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Coumarin-6-sulfonyl chloride
  • HY-N9531

    Bacterial Infection
    3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .
    3'-Hydroxyxanthyletin
  • HY-116931

    Others Others
    Kelletinin I is a coumarin compound with anti-HIV-1 activity.
    Kelletinin I
  • HY-N10169

    Others Others
    Edgeworin is a coumarin compound can be isolated from the root and stem of Edgeworthia .
    Edgeworin
  • HY-N10029

    Others Others
    Edgeworoside C (compound 5) is a coumarin isolated from the flower buds of Edgeworthia chrysantha .
    Edgeworoside C
  • HY-N2488
    Demethylsuberosin
    3 Publications Verification

    7-Demethylsuberosin

    Others Inflammation/Immunology
    Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai, and has anti-inflammatory activity .
    Demethylsuberosin
  • HY-N6658

    Others Cancer
    6-Hydroxy-4-methylcoumarin (compound 9) is a coumarins secondary metabolites and has anticancer activity .
    6-Hydroxy-4-methylcoumarin
  • HY-N10015

    Others Others
    7-Methoxy-4-methyl-coumarin-8-ol (compound 31) is a compound isolated from sour orange (Citrus aurantium) .
    7-Methoxy-4-methyl-coumarin-8-ol
  • HY-Y1298
    Methyl acetylacetate
    1 Publications Verification

    Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate

    Endogenous Metabolite Metabolic Disease
    Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives .
    Methyl acetylacetate
  • HY-N0573S

    7-Hydroxycoumarin-d5; Hydrangin-d5; NSC 19790-d5

    Endogenous Metabolite Apoptosis Cancer
    Umbelliferone-d5 is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.
    Umbelliferone-d5
  • HY-N2558

    Others Cancer
    Murrayone, a coumarin-containing compound extracted from M. paniculata, is the most bioactive substance in this species and is a cancer metastasis chemopreventive agent based on its unique pharmacological properties .
    Murrayone
  • HY-138145

    Fungal Bacterial Infection
    8-Acetyl-7-hydroxycoumarin is a coumarin-like compound found in Mexican patchouli (Tagetes lucida) that has anti-bacterial and anti-fungal activities .
    8-Acetyl-7-hydroxycoumarin
  • HY-N8618

    Others Others
    Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol was identified as one of the phenolic compounds isolated from Canadian maple syrup (MS-BuOH). It exhibited antioxidant properties along with other phenolic compounds and coumarins isolated from the syrup. These compounds showed varying degrees of antioxidant activity, with phenolic derivatives and coumarins showing superior activity, more so than lignans and flavonoids. This study marks the first time that 16 of the 23 phenolic compounds, including Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol, have been identified in maple syrup .
    Erythro-guaiacylglycerol-β-O-4'-dihydroconiferyl alcohol
  • HY-N9206

    Others Cardiovascular Disease
    Kimcuongin (compound 1)is a coumarin that can be found in Murraya paniculata. Kimcuongin shows vasorelaxant activity with an IC50 value of 37.7 μM. Kimcuongin can be used as a vasodilator .
    Kimcuongin
  • HY-163397

    Fungal Infection
    Antibacterial agent 196 (compound 6b) is a coumarin derivative containing oxime ether structure, and shows antifungal activity, with the EC50 of 0.46 μg/mL against Rhizoctonia solani .
    Antibacterial agent 196
  • HY-117754

    Cannabinoid Receptor Neurological Disease
    PSB-SB1202 (Compound 21a) is a phenyl coumarin compound. PSB-SB1202 is a CB1/CB2 agonist with EC50 values of 56 and 14 nM, and Ki values of 32 and 49 nM, respectively .
    PSB-SB1202
  • HY-N7650

    Biochemical Assay Reagents Others
    Dihydroseselin is a derivative of 7-hydroxycoumarin (HY-N0573). 7-hydroxycoumarin, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent
    Dihydroseselin
  • HY-D0066

    DCCH

    Fluorescent Dye Others
    7-Diethylaminocoumarin-3-carbohydrazide is a coumarin. 7-Diethylaminocoumarin-3-carbohydrazide can be used to detect sugar chains and quantify biological carbonyl compounds .
    7-Diethylaminocoumarin-3-carbohydrazide
  • HY-N0573R

    Endogenous Metabolite Apoptosis Cancer
    Umbelliferone (Standard) is the analytical standard of Umbelliferone. This product is intended for research and analytical applications. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.
    Umbelliferone (Standard)
  • HY-128105

    Others Others
    1,2-Dihydroxynaphthalene is an intermediate isolated from the metabolism of naphthalene and has been shown to be a precursor to the formation of naphthoquinones. 1,2-Dihydroxynaphthalene can be further metabolized by some bacteria (such as Pseudomonas) to compounds such as coumarins and salicylic acid .
    1,2-Dihydroxynaphthalene
  • HY-Y1298R

    Acetoacetate methyl ester (Standard); Methyl 3-oxobutanoate (Standard); Methyl acetoacetate (Standard)

    Endogenous Metabolite Metabolic Disease
    Methyl acetylacetate (Standard) is the analytical standard of Methyl acetylacetate. This product is intended for research and analytical applications. Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives .
    Methyl acetylacetate (Standard)
  • HY-N12875

    Tyrosinase Others
    Ailancoumarin E (Compound 5) is a derivative of Coumarin (HY-N0709). Ailancoumarin E exhibits antifeedant activity toward Plutella xylostella, and inhibits growth of third instar larva. Ailancoumarin E inhibits tyrosinase with IC50 of 14.21 μM .
    Ailancoumarin E
  • HY-N6856

    Bacterial Endogenous Metabolite Infection
    4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .
    4-Hydroxycoumarin
  • HY-149958

    Parasite Infection
    Antileishmanial agent-17 is a coumarin hybrid compound with antileishmanial effects (IC50 <0.78 μM). Antileishmanial agent-17 is safe to normal VERO cells. Antileishmanial agent-17 binds to folate pathway enzymes pteridine reductase and DHFR-TS. And Antileishmanial agent-17 shows the most potent with IC50 value of 0.40 μM against promastigote and 0.68 μM against amastigote, respectivley.
    Antileishmanial agent-17
  • HY-163457

    Aminoacyl-tRNA Synthetase Parasite Infection
    Antileishmanial agent-27 (compound 7j) is a benzothiazolo-coumarin derivative. Antileishmanial agent-27 is a competitive inhibitor of arginyl-tRNA synthetases (ArgRSs). Antileishmanial agent-27 shows selectivity toward ArgRS of Leishmania donovani (LdArgRS) than its human counterpart (HsArgRS), with IC50 values of 1.2 and 19 μM, respectively. Antileishmanial agent-27 possesses high pharmacokinetic properties .
    Antileishmanial agent-27
  • HY-135646

    Influenza Virus Infection Inflammation/Immunology
    Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities .
    Eleutheroside B1
  • HY-76779

    Others Cancer
    4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .
    4-(Chloromethyl)-7-hydroxycoumarin
  • HY-N0709S1

    Bacterial Fungal Isotope-Labeled Compounds Cancer
    Coumarin-d6 is deuterated labeled trans-2-Undecenal (HY-W127505). Trans-2-UndecenalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2-UndecenalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
    Coumarin-d6
  • HY-158402

    Bacterial Fungal Infection Inflammation/Immunology
    Anti-inflammatory agent 84 (Compound 4D) is a derivative of Coumarin (HY-N0709) with antimicrobial and anti-inflammatory activities. Anti-inflammatory agent 84 inhibits E. coli, Candida albicans, Staphylococcus aureus and methicillin-resistant S. aureus (MRSA), with MIC of 312, 156, 19 and 316 μg/mL, respectively. Anti-inflammatory agent 84 inhibits biofilm formation of S. aureus, E. coli and MRSA, with IC50 of 185, 321 and 99 μM, respectively. Anti-inflammatory agent 84 inhibits nitric oxide production in Lipopolysaccharide (HY-D1056)-stimulated RAW264.7 macrophage cell .
    Anti-inflammatory agent 84

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