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digestive

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

1

Screening Libraries

2

Biochemical Assay Reagents

7

Peptides

1

Inhibitory Antibodies

6

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131160
    Nuclease, Serratia marcescens

    Serratia marcescens nuclease

    		 Biochemical Assay Reagents Inflammation/Immunology
    Serratia marcescens nuclease (EC 3.1.30.2) is a nonspecific nuclease. Serratia marcescens nuclease has broad utility due to its potent digestive activity toward both DNA and RNA .
    Nuclease, Serratia marcescens
  • HY-B1136
    Menbutone

    Genabilic acid

    		 Drug Derivative Metabolic Disease
    Menbutone (Genabilic acid), an oxobutyric acid derivative, is a choleretic. Menbutone can be used to treat digestive upsets (loss of appetite, indigestion, toxemia, or hepatic and pancreatic insufficiencies) in a variety of animal species, including different farm animals (cattle, sheep, goats, pigs), as well as in dogs .
    Menbutone
  • HY-N7504
    Isopsoralenoside

    		Bacterial Infection Metabolic Disease Cancer
    Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .
    Isopsoralenoside
  • HY-109538
    Secretin (swine)

    		Secretin Receptor Neurological Disease Metabolic Disease
    Secretin (swine), a neuroendocrine hormone, is the first hormone to be identifie and is secreted by S cells that are localized primarily in the mucosa of the duodenum. Secretin also is a 27-amino acid peptide, which acts on secretin receptors. Secretin is expressed by cells in all mature enteroendocrine cell subsets and can be prompted by fatty acids. Secretin stimulates the secretion of pancreatic water and bicarbonate. Secretin exerts various effects in organs, can be used for the research of digestive system, central nervous system and energy metabolism .
    Secretin (swine)
  • HY-P9978
    Toripalimab

    		PD-1/PD-L1 Cancer
    Toripalimab is the first domestic anti-tumor PD-1 antibody in China. Toripalimab is a selective, recombinant, humanized monoclonal antibody against PD-1. Toripalimab is able to bind to PD-1 and block the interaction with its ligands. Toripalimab has exhibited primary anti-tumor effects in tumors such as melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma and urothelial carcinoma .
    Toripalimab
  • HY-149516
    Human enteropeptidase-IN-3

    		Enteropeptidase Others
    Human enteropeptidase-IN-3 is an enteropeptidase inhibitor. Human enteropeptidase-IN-3 exhibits enteropeptidase activity and long duration of inhibitory state. Human enteropeptidase-IN-3 can be used for intetinal digestive related diseases research .
    Human enteropeptidase-IN-3
  • HY-B2118
    Pancreatin

    		Biochemical Assay Reagents Endocrinology
    Pancreatin is the porcine pancreas extract (PPE) which contains the main pancreatic digestive enzymes.
    Pancreatin
  • HY-109538R
    Secretin (swine) (Standard)

    		Secretin Receptor Neurological Disease Metabolic Disease
    Secretin (swine) (Standard) is the analytical standard of Secretin (swine). This product is intended for research and analytical applications. Secretin (swine), a neuroendocrine hormone, is the first hormone to be identifie and is secreted by S cells that are localized primarily in the mucosa of the duodenum. Secretin also is a 27-amino acid peptide, which acts on secretin receptors. Secretin is expressed by cells in all mature enteroendocrine cell subsets and can be prompted by fatty acids. Secretin stimulates the secretion of pancreatic water and bicarbonate. Secretin exerts various effects in organs, can be used for the research of digestive system, central nervous system and energy metabolism .
    Secretin (swine) (Standard)
  • HY-A0125
    Alizapride

    		Dopamine Receptor Neurological Disease
    Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders .
    Alizapride
  • HY-P2433
    SNF-8814

    		Biochemical Assay Reagents Others
    SNF-8814 is a cholecystokinin analog. SNF-8814 can be used in digestive system related research .
    SNF-8814
  • HY-A0125A
    Alizapride hydrochloride

    		Dopamine Receptor Neurological Disease Cancer
    Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders .
    Alizapride hydrochloride
  • HY-N7762
    Chrysanthellin A

    		Others Others
    Chrysanthellin A is the main saponin-based compound from the extract of Chrysanthellum americanum. Chrysanthellin A can be used in the reserach of digestive impairments .
    Chrysanthellin A
  • HY-B0326
    Alibendol

    		Others Endocrinology
    Alibendol can be taken orally. It has anti-spasmodic properties and promotes bile secretion, making it useful for research on digestive system issues like indigestion, nausea, vomiting, and constipation .
    Alibendol
  • HY-B2218D
    Magnesium hydroxide, 99%(KT)

    Magnesium dihydroxide, 99%(KT)

    		 Biochemical Assay Reagents Endocrinology
    Magnesium hydroxide, 99%(KT) (Magnesium dihydroxide, 99%(KT)) is a biochemical agent. Magnesium hydroxide, 99%(KT) is a non-absorbable antacid used to treat acidic digestive diseases .
    Magnesium hydroxide, 99%(KT)
  • HY-121226
    Karakin

    		Biochemical Assay Reagents Metabolic Disease
    Karakin is a nitro toxin derived from Lotus pedunculatus. Karakin is hydrolysed rapidly to 3-NPA in gut tissue of grass grub larvae, which is enzymic and occurred mainly in the upper half of the digestive tract .
    Karakin
  • HY-E70130
    Snailase, Snail gastrointestinal

    		Others Others
    Snailase, Snail gastrointestinal is an enzyme mixture composed of more than 20 enzymes, which is often used for enzymatic hydrolysis of purified flavonoid glycosides. Snailase can be obtained from the digestive tract and includes cellulase, sucrase, hemicellulase, pectinase, polygalacturonase, protease, etc .
    Snailase, Snail gastrointestinal
  • HY-129047D
    Trypsin, Human Pancreas

    		Ser/Thr Protease Kallikrein Protease Activated Receptor (PAR) Cardiovascular Disease Inflammation/Immunology
    Trypsin, Human Pancreas is a serine protease that hydrolyses proteins into peptides and amino acids, and is an improtant enzyme for digestive system. Trypsin, Human Pancreas activates kallikrein and regulates the blood pressure. Trypsin, Human Pancreas is an activator for PAR, thereby regulating cellular inflammatory and immune responses .
    Trypsin, Human Pancreas
  • HY-P1465
    Secretin (28-54), human

    Human secretin

    		 Secretin Receptor Metabolic Disease Cancer
    Secretin (28-54), human is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors .
    Secretin (28-54), human
  • HY-142090
    Donetidine

    SK&F 93574

    		 Histamine Receptor Others
    Donetidine (SK&F 93574) is an antagonist for histamine H2 receptor, that promotes histamine release in beagle dog models .
    Donetidine
  • HY-P1465A
    Secretin (28-54), human TFA

    Human secretin TFA

    		 Secretin Receptor Metabolic Disease Cancer
    Secretin (28-54), human TFA is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors .
    Secretin (28-54), human TFA
  • HY-119722
    Butafosfan

    		Endogenous Metabolite Others
    Butafosfan is a phosphate containing compound, which is used as active ingredient of veterinary drug. Butafosfan can stimulate the appetite, immune system and digestive function, improves liver and muscle function of dogs. Butafosfan can mitigate the adverse effects of Dexamethasone (HY-14648) on liver and pancreatic function in dogs .
    Butafosfan
  • HY-161949
    AP-6

    		Potassium Channel Neurological Disease
    AP-6 is a selective inhibitor of TMEM175 with activity in modulating lysosomal function. Acute inhibition of TMEM175 by AP-6 increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. AP-6 may be used in Parkinson's disease research .
    AP-6
  • HY-P10220
    NOTA-COG1410

    		Radionuclide-Drug Conjugates (RDCs) Biochemical Assay Reagents Others
    NOTA-COG1410 forms triggering receptor expressed on myeloid cells 2 (TREM2) targeting radioligand for discovery and diagnosis of digestive system tumors through positron emission tomography/computed tomography . NOTA-COG1410 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
    NOTA-COG1410
  • HY-148035
    Plm IV inhibitor-2

    		Parasite Infection
    Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites .
    Plm IV inhibitor-2
  • HY-33878
    2-PPA

    		Potassium Channel Neurological Disease
    2-PPA is a selective inhibitor of TMEM175 (IC50=32 μM) with activity in modulating lysosomal function. Acute inhibition of TMEM175 by 2-PPA increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. 2-PPA can be used in the study of Parkinson's disease .
    2-PPA
  • HY-133890
    Tauro-α-muricholic acid

    T-α-MCA

    		 Endogenous Metabolite FXR Cardiovascular Disease Others Metabolic Disease
    Tauro-alpha-muricholic acid (T-alpha-MCA) is a bile acid that belongs to a class of compounds that are synthesized in the liver and play an important role in the digestive process. Tauro-α-muricholic acid activates Farni X receptors (FXR) which are involved in the regulation of bile acid synthesis, metabolism and transport. Tauro-alpha-muricholic acid can be used in the study of metabolic syndrome and cardiovascular disease .
    Tauro-α-muricholic acid
  • HY-W587530
    6-Oxolithocholic acid

    6-Ketolithocholic acid

    		 Endogenous Metabolite Apoptosis Endocrinology
    6-Oxolithocholic acid is a bile acid metabolite derived from Lithocholic acid (HY-B0172). 6-Oxolithocholic acid has high cytotoxicity and can induce apoptosis, especially in hepatocytes. 6-Oxolithocholic acid can participate in the regulation of bile acid metabolism and synthesis and affect the metabolic pathway of cholesterol. 6-Oxolithocholic acid can be used to study the role of bile acids in health and disease, especially in the context of digestive and liver diseases .
    6-Oxolithocholic acid
  • HY-162390
    α-Amylase/α-Glucosidase-IN-11

    		Amylases Glycosidase Endocrinology
    α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is a isoxazolidine-isatin hybrid with significant antidiabetic activity. α-Amylase/α-Glucosidase-IN-11 competitively inhibits α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM), two key digestive enzymes. α-Amylase/α-Glucosidase-IN-11 does not cross the blood-brain barrier .
    α-Amylase/α-Glucosidase-IN-11
  • HY-W127485
    cis-9,10-Methyleneoctadecanoic Acid

    		Biochemical Assay Reagents Others
    cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and in the digestive glands of P. globosa. It is a component of the cell membrane of Staphylococcus aureus, and levels were reduced after treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.
    cis-9,10-Methyleneoctadecanoic Acid
  • HY-129516
    A-70874

    		Cholecystokinin Receptor Metabolic Disease
    A-70874 is a tyrosine-free tetrapeptide analog of cholecystokinin (30-33) (CCK-4). A-70874 is an agonist that stimulates pancreatic amylase release and a partial agonist that stimulates pancreatic phosphoinositide decomposition. A-70874 has an IC50 of 4.9 nM for the guinea pig pancreatic CCK receptor. Cholecystokinin (CCK) receptors are divided into CCK-A (digestive tract) and CCK-B (brain). A-70874 has an affinity of 1.6 μM for the CCK-B/gastrin receptor .
    A-70874
  • HY-N2252
    Licarin A

    (+)-Licarin A

    		 TNF Receptor Prostaglandin Receptor COX Neurological Disease Metabolic Disease Inflammation/Immunology
    Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression .
    Licarin A
  • HY-N7503
    Psoralenoside

    		Histamine Receptor Calcium Channel Calmodulin Infection Metabolic Disease Cancer
    Psoralenoside is a benzofuran glycoside from Psoralea corylifolia . Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol) . Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .
    Psoralenoside

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