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Results for "

hydrolyse

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin-converting Enzyme (ACE) (3) Apoptosis (1) COX (1) Endogenous Metabolite (2) Fluorescent Dye (4) Proteasome (1) Reactive Oxygen Species (1)
By Research Areas:	Cardiovascular Disease (4) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-121657

Ornidazole diol Ro 11-2616	Others	Others
Ornidazole diol (Ro 11-2616) is a diol produced by ornidazole rapidly hydrolysing in basic solutions .

HY-123053

Z-Leu-Leu-Glu-AMC Z-LLE-AMC	Proteasome	Others
Z-Leu-Leu-Glu-AMC is a substrate peptide, and can be used for determination of postacidic-like hydrolysing activity of 20S proteasome

HY-Y1787

Dimethyl malonate	Apoptosis	Neurological Disease
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-D1699

PFB-FDG	Fluorescent Dye	Others
PFB-FDG is a non-fluorescent galactosidase substrate that can be hydrolysed to green fluorescent PFB-F (Ex=485 nm, Em=535 nm). PFB-FDG can be used for the determination of β-galactosidase activity .

HY-P4427

Z-VAN-AMC	Fluorescent Dye	Others
Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity .

HY-121657R

Ornidazole diol (Standard)	Others	Others
Ornidazole diol (Standard) is the analytical standard of Ornidazole diol. This product is intended for research and analytical applications. Ornidazole diol (Ro 11-2616) is a diol produced by ornidazole rapidly hydrolysing in basic solutions .

HY-124178

(R)-Levrazoxane (R)-ICRF 186	Others	Metabolic Disease
(R)-Levrazoxane ((R)-ICRF 186) is enzymatically hydrolysed to one-ring open intermediates by dihydropyrimidine amidohydrolase (DPHase), which is present in the liver and kidney. The radiosensitizing efficiency of (R)-Levrazoxane towards EMT6 mouse mammary tumour cells is greater than that of Dexrazoxane (HY-B0581). (R)-Levrazoxane is promising for research of liver and kidney related diseases .

HY-E70103

α-L-Arabinofuranosidase	Others	Others
α-L-Arabinofuranosidase is a glycosidic hydrolase. α-L-Arabinofuranosidase hydrolyse the nonreducing termini of the a-l-arabinofuranosyl residues as side chains of arabinoxylan, arabinan and arabinogalactan .

HY-137103

BTC-AM	Fluorescent Dye	Others
BTC-AM is a low affinity calcium indicator. BTC-AM has substantial calcium-independent fluorescence at all excitation wavelengths. BTC-AM is readily loaded into neurons and is rapidly hydrolysed .

HY-121226

Karakin	Others	Metabolic Disease
Karakin is a nitro toxin derived from Lotus pedunculatus. Karakin is hydrolysed rapidly to 3-NPA in gut tissue of grass grub larvae, which is enzymic and occurred mainly in the upper half of the digestive tract .

HY-121322

Neoagarobiose	Others	Others
Neoagarobiose has both a moisturizing effect on skin and a whitening effect on melanoma cells. RagaA11 is an endo-type beta-agarase hydrolysing not only agarose, but also neoagarotetraose, to yield neoagarobiose as the final main product .

HY-B0592

Trandolapril RU44570	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-B0592A

Trandolapril hydrochloride RU44570 hydrochloride	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Trandolapril (RU44570) hydrochloride is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolapril hydrochlorideat. Trandolapril hydrochloride is an orally active angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-19675

Naproxen etemesil LT-NS 001; MX 1094	COX	Inflammation/Immunology
Naproxen etemesil is a lipophilic, non-acidic, inactive proagent of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC₅₀s of 8.72 and 5.15 μM, respectively in cell assay.

HY-B0757A

(±)-α-Tocopherol nicotinate rel-Vitamin E Nicotinate	Reactive Oxygen Species Endogenous Metabolite	Cardiovascular Disease
(±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases .

HY-P3173

Pullulanase R-enzyme	Endogenous Metabolite	Others
Pullulanase (R-enzyme) is a starch debranching enzyme, is often used in biochemical studies. Pullulanase hydrolyses the α-1,6 glucosidic linkages in starch, amylopectin, pullulan, and related oligosaccharides. Pullulanase converts polysaccharide into small fermentative sugars during saccharification .

HY-B0592R

Trandolapril (Standard)	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Trandolapril (Standard) is the analytical standard of Trandolapril. This product is intended for research and analytical applications. Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-W209628

Methyl 2-acetoxybenzoate Methyl acetylsalicylate	Others	Inflammation/Immunology
Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) is a safe and simple anti-inflammatory aspirin prodrug. Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) can be chemical or enzymatically hydrolysed to methyl 2-hydroxy benzoate. Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) can be used as analgesic agent in liniments and also inflammatory diseases research .

HY-131131

5-CFDA-AM	Fluorescent Dye	Others
5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell .

Cat. No.	Product Name	Type

HY-D1699

PFB-FDG	Fluorescent Dyes/Probes
PFB-FDG is a non-fluorescent galactosidase substrate that can be hydrolysed to green fluorescent PFB-F (Ex=485 nm, Em=535 nm). PFB-FDG can be used for the determination of β-galactosidase activity .

HY-131131

5-CFDA-AM	Fluorescent Dyes/Probes
5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell .

5-CFDA-AM

Fluorescent Dyes/Probes

5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell .