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Results for "

neuromuscular agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (2) Biochemical Assay Reagents (1) Cholinesterase (ChE) (1) nAChR (13) Parasite (1) Sodium Channel (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (4) Infection (1) Inflammation/Immunology (3) Neurological Disease (20)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0079

Sugammadex sodium Org25969	Others	Cardiovascular Disease Neurological Disease Cancer
Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex sodium shows nephroprotective effect in ischemia-reperfusion injury .

HY-B0743A

Pipecuronium bromide	nAChR	Neurological Disease
Pipecuronium bromide is a potent long-acting nondepolarizing steroidal neuromuscular blocking agent (NMBA), and a bisquaternary ammonium compound. Pipecuronium bromide is a powerful competitive nAChR antagonist with a Kd of 3.06 μM .

HY-13596

Cisatracurium besylate 1 Publications Verification 51W89 besylate; Cisatracurium besilate	nAChR Autophagy	Neurological Disease Cancer
Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

HY-B0570

Decamethonium Bromide	nAChR	Neurological Disease
Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.

HY-B1700B

(S,S)-Mivacurium dichloride	Others	Neurological Disease
(S,S)-Mivacurium dichloride (Compound 29a) is a neuromuscular blocking agent and causes muscle relaxation .

HY-B0079A

Sugammadex Org25969 free acid	Others	Cardiovascular Disease Neurological Disease
Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury .

HY-U00162

SZ1676	Others	Neurological Disease
SZ1676 is a derivative of SZ1677, which is a neuromuscular blocking agent.

HY-126032

Morantel	Parasite	Infection
Morantel is an antinematodal agent. Morantel exhibits neuromuscular blocking properties .

HY-13596R

Cisatracurium besylate (Standard)	nAChR Autophagy	Neurological Disease Cancer
Cisatracurium (besylate) (Standard) is the analytical standard of Cisatracurium (besylate). This product is intended for research and analytical applications. Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

HY-A0215

Doxacurium chloride BW-A 938U; Nuromax	nAChR	Neurological Disease
Doxacurium chloride (BW A938U) is a potent non-depolarizing neuromuscular blocking agent. Doxacurium chloride binds to cholinergic receptors to antagonize acetylcholine, resulting in a block of neuromuscular transmission. Doxacurium chloride can be used for the research of neurological diseases .

HY-B0292

Atracurium BW-33A free acid	nAChR	Cardiovascular Disease Inflammation/Immunology
tracurium (BW-33A free acid) is a potent, competitive and non-depolarizing neuromuscular blocking agent.Atracurium also is an AChR receptor antagonist. Atracurium induces bronchoconstriction and neuromuscular blockade. Atracurium promotes astroglial differentiation .

HY-B0292A

Atracurium besylate BW-33A	nAChR	Neurological Disease Inflammation/Immunology Cancer
Atracurium (BW-33A) besylate is a potent, competitive and non-depolarizing neuromuscular blocking agent. Atracurium besylate also is an AChR receptor antagonist. Atracurium besylate induces bronchoconstriction and neuromuscular blockade. Atracurium besylate promotes astroglial differentiation .

HY-127147

Fazadinium bromide AH 8165 bromide	Others	Others
Fazadinium bromide (AH 8165 bromide) is a neuromuscular blocking agent, that can prevent the muscle contraction. Fazadinium bromide can be used as a muscle relaxant during anesthesia .

HY-W127670

Decamethonium iodide	Biochemical Assay Reagents	Others
Decamethonium (iodide) is an organic compound containing ammonium and iodide ions. It is commonly used as a neuromuscular blocking agent in anesthesia to induce muscle relaxation during surgery. Decamethonium Iodide acts by binding to nicotinic acetylcholine receptors (nAChRs) in the neuromuscular junction, causing depolarization block and subsequent skeletal muscle paralysis. In addition, it can also serve as a reference standard for pharmacological studies of nAChRs.

HY-B0292AR

Atracurium besylate (Standard)	nAChR	Neurological Disease Inflammation/Immunology Cancer
Atracurium (besylate) (Standard) is the analytical standard of Atracurium (besylate). This product is intended for research and analytical applications. Atracurium (BW-33A) besylate is a potent, competitive and non-depolarizing neuromuscular blocking agent. Atracurium besylate also is an AChR receptor antagonist. Atracurium besylate induces bronchoconstriction and neuromuscular blockade. Atracurium besylate promotes astroglial differentiation .

HY-13709

Gantacurium chloride AV 4430A; GW 280430A	Others	Neurological Disease
Gantacurium is an ultrashort-acting, nondepolarizing neuromuscular blocking agent that is degraded by nonenzymatic binding to L-cysteine under physiological conditions. Gantacurium causes a decrease in mean arterial pressure and an increase in heart rate .

HY-B0118A

Vecuronium bromide ORG NC 45	nAChR	Neurological Disease Cancer
Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia .

HY-126645

Atelopidtoxin	Sodium Channel	Cardiovascular Disease
Atelopidtoxin (zetekitoxin) is a toxin (LD₅₀=0.016 mg/kg for mice), which can be isolated from Panamanian frog Atelopus zeteki. Atelopidtoxin causes hypotension and ventricular fibrillation in rabbits. Atelopidtoxin an inhibitor for sodium channel .

HY-B1700A

Mivacurium dichloride	nAChR	Neurological Disease
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-137788

α-Conotoxin GI	nAChR	Neurological Disease
α-Conotoxin GI has high affinity for nAChR.α-Conotoxin GI is a short peptide toxin that can be isolated from the venom of Conus geographus.α-Conotoxin GI has the similar activity with neuromuscular blocking agent .

HY-161118

MB327	Others	Neurological Disease
MB327 is a bipyridine nonoxime compound that restores neuromuscular function. MB327 restores the activity of nicotinamide acetylcholine receptors (nAChRs) for carbachol desensitization in a typical type II PAM manner. MB327 can neutralize nerve agent poisoning .

HY-B0118AR

Vecuronium bromide (Standard)	nAChR	Neurological Disease Cancer
Vecuronium (bromide) (Standard) is the analytical standard of Vecuronium (bromide). This product is intended for research and analytical applications. Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia .

HY-B2152

Hemicholinium 3 Hemicholinium dibromide	Cholinesterase (ChE)	Neurological Disease
Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a K_i value of 25 nM. Hemicholinium 3, a neuromuscular blocking agent which inhibits the synthesis and the release of acetylcholine (ACh) . Hemicholinium 3 inhibits the Epibatidine-evoked contraction and [ ³H]acetylcholine release with IC50s of 897 nM and 693 nM, respectively .

HY-B1700AR

Mivacurium dichloride (Standard)	nAChR	Neurological Disease
Mivacurium (dichloride) (Standard) is the analytical standard of Mivacurium (dichloride). This product is intended for research and analytical applications. Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-121670

Ambenoxan	Others	Neurological Disease
Ambenoxan is a central nervous system-acting skeletal muscle relaxant that is effective in mice, rats, rabbits, dogs, and monkeys without loss of the righting reflex. It has no peripheral neuromuscular blocking effects and significantly reduces or eliminates decerebrate rigidity in rabbits, but does not antagonize the effects of strychnine, leptazol, or tremorine. Like other central nervous system depressants, ambenoxan prolongs sleep duration with hexobarbitone, but it has no local anesthetic effects. In anesthetized cats, the agent lowers blood pressure and reduces the pressor response to epinephrine, but has no effect on norepinephrine.

Cat. No.	Product Name	Type

HY-W127670

Decamethonium iodide	Cell Assay Reagents
Decamethonium (iodide) is an organic compound containing ammonium and iodide ions. It is commonly used as a neuromuscular blocking agent in anesthesia to induce muscle relaxation during surgery. Decamethonium Iodide acts by binding to nicotinic acetylcholine receptors (nAChRs) in the neuromuscular junction, causing depolarization block and subsequent skeletal muscle paralysis. In addition, it can also serve as a reference standard for pharmacological studies of nAChRs.

Decamethonium iodide

Cell Assay Reagents

Decamethonium (iodide) is an organic compound containing ammonium and iodide ions. It is commonly used as a neuromuscular blocking agent in anesthesia to induce muscle relaxation during surgery. Decamethonium Iodide acts by binding to nicotinic acetylcholine receptors (nAChRs) in the neuromuscular junction, causing depolarization block and subsequent skeletal muscle paralysis. In addition, it can also serve as a reference standard for pharmacological studies of nAChRs.

Cat. No.	Product Name	Target	Research Area

HY-137788

α-Conotoxin GI	nAChR	Neurological Disease
α-Conotoxin GI has high affinity for nAChR.α-Conotoxin GI is a short peptide toxin that can be isolated from the venom of Conus geographus.α-Conotoxin GI has the similar activity with neuromuscular blocking agent .

Atelopidtoxin	Structural Classification Natural Products Animals Source classification Animal Venoms	Sodium Channel
Atelopidtoxin (zetekitoxin) is a toxin (LD₅₀=0.016 mg/kg for mice), which can be isolated from Panamanian frog Atelopus zeteki. Atelopidtoxin causes hypotension and ventricular fibrillation in rabbits. Atelopidtoxin an inhibitor for sodium channel .

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