Search Result
Results for "
oligopeptides
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P10294
-
|
|
Amyloid-β
|
Others
|
|
Oligopeptide P11-4 is an α-peptide that can be self-assembled into β-sheet amyloids with a hydrogel appearance at low pH. Oligopeptide P11-4 can be used in biomimetic mineralization, enamel regeneration and oral care agent .
|
-
-
- HY-106279
-
|
|
GnRH Receptor
|
Inflammation/Immunology
|
|
EA-230 is a synthetic oligopeptide originally derived from beta-human chorionic gonadotropin (beta-hCG) lysates. EA-230 has anti-inflammatory effects and can be used for the research of sepsis .
|
-
-
- HY-120756
-
-
-
- HY-P5768
-
|
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Biochemical Assay Reagents
|
Others
|
|
WSHPQFEKWSHPQFEK is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. WSHPQFEKWSHPQFEK can be used to construct DNA-protein hybrids .
|
-
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- HY-P5768A
-
|
|
Biochemical Assay Reagents
|
Cancer
|
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WSHPQFEKWSHPQFEK TFA is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. WSHPQFEKWSHPQFEK TFA can be used to construct DNA-protein hybrids .
|
-
-
- HY-P0148
-
|
Hexaglycine
|
Bacterial
|
Others
|
|
Gly6 (Hexaglycine) is a linear glycine oligopeptide with six glycines .
|
-
-
- HY-120455
-
-
-
- HY-P3729
-
-
-
- HY-P3497
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
|
-
-
- HY-P3497A
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
|
-
-
- HY-P0096
-
|
|
Tyrosinase
Sirtuin
|
Inflammation/Immunology
Endocrinology
|
|
Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation .
|
-
-
- HY-P5251
-
-
-
- HY-P5256
-
|
|
Bacterial
|
Others
|
|
Oligopeptide-20 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient .
|
-
-
- HY-P5258
-
|
|
EGFR
|
Metabolic Disease
|
|
Oligopeptide-41 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .
|
-
-
- HY-N10477
-
|
L-γ-Glutamyl-L-arginine
|
Amino Acid Derivatives
|
Others
|
|
gamma-Glutamylarginine, an γ-glutamic acid oligopeptide, can be isolated from Panax ginseng .
|
-
-
- HY-P4488
-
|
|
Dipeptidyl Peptidase
|
Others
|
|
H-Pro-Pro-Gln-OH is a oligopeptide with excellent dipeptidyl peptidase-IV (DPP-IV) inhibitory activity .
|
-
-
- HY-119982
-
|
Cicloral
|
Bacterial
|
Metabolic Disease
|
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Cyclamide (Cicloral), an oligopeptide, can be produced by cyanobacteria algae strains. Cyclamide can be used for the research of diabetes mellitus .
|
-
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- HY-126770
-
|
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Fungal
|
Infection
|
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Rhizocticin A is an antifungal phosphono-oligopeptide against Ascodesmis, Plicaria, Rhizoctonia with MIC of 3.5 μg/mL. Rhizocticin A produces toxic L-2-Amino-5-phospho-3-cis-pentenoic acid (L-APPA), which may interfere with cell metabolism .
|
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- HY-172275A
-
|
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Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG2000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB can be used for drug delivery .
|
-
-
- HY-172275
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG1000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB can be used for drug delivery .
|
-
-
- HY-172275B
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB can be used for drug delivery .
|
-
-
- HY-P10765
-
|
|
Peptide-Drug Conjugates (PDCs)
Topoisomerase
|
Cancer
|
|
DTS-108 is a prodrug of SN38 (HY-13704) (a Topoisomerase I inhibitor). DTS-108 is a conjugate generated by linking SN38 to a human oligopeptide via an esterase sensitive cross-linker. DTS-108 exhibits anti-tumor activity against colorectal, lung, and mammary cancer .
|
-
-
- HY-111956B
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors .
|
-
-
- HY-P1704
-
|
11-Demethylcyclosporin A
|
Biochemical Assay Reagents
|
Infection
|
|
Cyclosporin E (11-Demethylcyclosporin A) is a cyclic oligopeptide that can be isolated from fungi such as TTrichoderma polysporum and other imperfect fungi. Cyclosporin E belongs to the Cyclosporins family. Cyclosporin E can be used for studying the structure-activity relationships and molecular dynamic properties of cyclosporin compounds. As a structural control compound, Cyclosporin E holds significant research value in the fields of medicinal chemistry and biophysics .
|
-
-
- HY-111956
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors .
|
-
-
- HY-111956A
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors .
|
-
-
- HY-16969
-
Dihexa
5 Publications Verification
PNB-0408; N-hexanoic-Try-Ile-(6)-amino hexanoic amide; Hexanoyl-Tyr-Ile-Ahx-NH2
|
c-Met/HGFR
|
Neurological Disease
|
|
Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (Kd=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease .
|
-
-
- HY-129407
-
|
Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II
|
Proteasome
|
Infection
|
|
AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.
|
-
-
- HY-P4160
-
|
THG113.31; ILGHXDYK
|
Prostaglandin Receptor
|
Endocrinology
|
|
PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca 2+-dependent large-conductance K +-channel in human myometrial cells .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-111956B
-
|
|
Fluorescent Dyes/Probes
|
|
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors .
|
-
- HY-111956
-
|
|
Fluorescent Dyes/Probes
|
|
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors .
|
-
- HY-111956A
-
|
|
Fluorescent Dyes/Probes
|
|
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors .
|
| Cat. No. |
Product Name |
Type |
-
- HY-172275A
-
|
|
Drug Delivery
|
|
DSPE-PEG2000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB can be used for drug delivery .
|
-
- HY-172275
-
|
|
Drug Delivery
|
|
DSPE-PEG1000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB can be used for drug delivery .
|
-
- HY-172275B
-
|
|
Drug Delivery
|
|
DSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB can be used for drug delivery .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P3422
-
|
|
Peptides
|
Cancer
|
|
NH2-AKA-COOH is a oligopeptide compoused of Ala-Lys-Ala.
|
-
- HY-P10294
-
|
|
Amyloid-β
|
Others
|
|
Oligopeptide P11-4 is an α-peptide that can be self-assembled into β-sheet amyloids with a hydrogel appearance at low pH. Oligopeptide P11-4 can be used in biomimetic mineralization, enamel regeneration and oral care agent .
|
-
- HY-P3421
-
|
|
Peptides
|
Cancer
|
|
NH2-SSK-COOH is a oligopeptide compoused of Ser-Ser-Lys.
|
-
- HY-P3420
-
|
|
Peptides
|
Cancer
|
|
NH2-ASK-COOH is a oligopeptide compoused of Ala-Ser-Lys.
|
-
- HY-P3423
-
|
|
Peptides
|
Cancer
|
|
NH2-KAA-COOH is a oligopeptide compoused of Lys-Ala-Ala.
|
-
- HY-P5768
-
|
|
Biochemical Assay Reagents
|
Others
|
|
WSHPQFEKWSHPQFEK is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. WSHPQFEKWSHPQFEK can be used to construct DNA-protein hybrids .
|
-
- HY-P5768A
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
WSHPQFEKWSHPQFEK TFA is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. WSHPQFEKWSHPQFEK TFA can be used to construct DNA-protein hybrids .
|
-
- HY-P0148A
-
|
Hexaglycine hydrochloride
|
Peptides
|
Others
|
|
Gly6 hydrochloride (Hexaglycine hydrochloride) is a linear glycine oligopeptide with six glycines .
|
-
- HY-P0148
-
|
Hexaglycine
|
Bacterial
|
Others
|
|
Gly6 (Hexaglycine) is a linear glycine oligopeptide with six glycines .
|
-
- HY-P2634
-
|
|
Peptides
|
Metabolic Disease
|
|
Acetyl pentapeptide-1 is a pentapeptide. Acetyl pentapeptide-1 combined with other oligopeptides can enhance the skin barrier function.
|
-
- HY-P3729
-
-
- HY-106279
-
|
|
GnRH Receptor
|
Inflammation/Immunology
|
|
EA-230 is a synthetic oligopeptide originally derived from beta-human chorionic gonadotropin (beta-hCG) lysates. EA-230 has anti-inflammatory effects and can be used for the research of sepsis .
|
-
- HY-P3497
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
|
-
- HY-P3497A
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
|
-
- HY-P0096
-
|
|
Tyrosinase
Sirtuin
|
Inflammation/Immunology
Endocrinology
|
|
Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation .
|
-
- HY-P5259
-
|
|
Peptides
|
Metabolic Disease
|
|
Oligopeptide-6 is a bioactive peptide with moisturizing effect and has been reported used as a cosmetic ingredient .
|
-
- HY-P5251
-
-
- HY-P5256
-
|
|
Bacterial
|
Others
|
|
Oligopeptide-20 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient .
|
-
- HY-P5255
-
|
|
Peptides
|
Infection
|
|
Oligopeptide-10 is a bioactive peptide with anti-microbial effect and has been reported used as a cosmetic ingredient .
|
-
- HY-P5258
-
|
|
EGFR
|
Metabolic Disease
|
|
Oligopeptide-41 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .
|
-
- HY-P5260
-
|
|
Peptides
|
Metabolic Disease
|
|
Oligopeptide-74 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .
|
-
- HY-P5257
-
|
CG-EDP3
|
Peptides
|
Others
|
|
Oligopeptide-24 (CG-EDP3) s a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient .
|
-
- HY-W142467A
-
|
|
Peptides
|
Others
|
|
Tetraglycine hydrochloride is a oligopeptide composed of four glycine monomers .
|
-
- HY-W142467
-
|
|
Peptides
|
Others
|
|
Tetraglycine is a oligopeptide composed of four glycine monomers .
|
-
- HY-P4488
-
|
|
Dipeptidyl Peptidase
|
Others
|
|
H-Pro-Pro-Gln-OH is a oligopeptide with excellent dipeptidyl peptidase-IV (DPP-IV) inhibitory activity .
|
-
- HY-P1973
-
|
|
Peptides
|
Inflammation/Immunology
|
|
Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation .
|
-
- HY-107130
-
|
GM604
|
Peptides
|
Neurological Disease
|
|
Alirinetide (GM604) is an oligopeptide containing 6 amino acids. Alirinetide can cross the blood-brain barrier and can be used for the research of multiple neurodegenerative diseases .
|
-
- HY-P10765
-
|
|
Peptide-Drug Conjugates (PDCs)
Topoisomerase
|
Cancer
|
|
DTS-108 is a prodrug of SN38 (HY-13704) (a Topoisomerase I inhibitor). DTS-108 is a conjugate generated by linking SN38 to a human oligopeptide via an esterase sensitive cross-linker. DTS-108 exhibits anti-tumor activity against colorectal, lung, and mammary cancer .
|
-
- HY-111956B
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors .
|
-
- HY-P1704
-
|
11-Demethylcyclosporin A
|
Biochemical Assay Reagents
|
Infection
|
|
Cyclosporin E (11-Demethylcyclosporin A) is a cyclic oligopeptide that can be isolated from fungi such as TTrichoderma polysporum and other imperfect fungi. Cyclosporin E belongs to the Cyclosporins family. Cyclosporin E can be used for studying the structure-activity relationships and molecular dynamic properties of cyclosporin compounds. As a structural control compound, Cyclosporin E holds significant research value in the fields of medicinal chemistry and biophysics .
|
-
- HY-111956
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors .
|
-
- HY-111956A
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors .
|
-
- HY-P4160
-
|
THG113.31; ILGHXDYK
|
Prostaglandin Receptor
|
Endocrinology
|
|
PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca 2+-dependent large-conductance K +-channel in human myometrial cells .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N10477
-
-
-
- HY-126770
-
-
-
- HY-P1704
-
|
11-Demethylcyclosporin A
|
Structural Classification
Microorganisms
Cyclopeptides
Source classification
|
Biochemical Assay Reagents
|
|
Cyclosporin E (11-Demethylcyclosporin A) is a cyclic oligopeptide that can be isolated from fungi such as TTrichoderma polysporum and other imperfect fungi. Cyclosporin E belongs to the Cyclosporins family. Cyclosporin E can be used for studying the structure-activity relationships and molecular dynamic properties of cyclosporin compounds. As a structural control compound, Cyclosporin E holds significant research value in the fields of medicinal chemistry and biophysics .
|
-
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