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Results for "

pH sensitivity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Fluorescent Dye (7) Liposome (1) Reactive Oxygen Species (2)
By Research Areas:	Cancer (2) Infection (1) Inflammation/Immunology (3)
Oligonucleotides:	Pegylated Lipids (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Oligonucleotides

Targets Recommended: HIF/HIF Prolyl-Hydroxylase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W440988

DOPE-mPEG, MW 2000	Liposome	Others
DOPE-mPEG, MW 2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG, MW 2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .

HY-D1677

5(6)-Carboxynaphthofluorescein	Fluorescent Dye	Others
5(6)-Carboxynaphthofluorescein is a pH-dependent fluorophore. 5(6)-Carboxynaphthofluorescein shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. 5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator (Ex/Em=593/668 nm) .

HY-D1591

BODIPY R6G methyl ester	Fluorescent Dye	Others
BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .

HY-128945

CL2A	ADC Linker	Inflammation/Immunology Cancer
CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker .

HY-130027

HKOCl-4 1 Publications Verification BXY2142	Fluorescent Dye	Others
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. E_x: 530 nm; E_m 557 nm.

HY-128945A

CL2A TFA	ADC Linker	Inflammation/Immunology Cancer
CL2A TFA is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A TFA is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker .

HY-D1156A

HKSOX-1m (5/6-mixture) hydrobromide 1 Publications Verification	Reactive Oxygen Species Fluorescent Dye	Others
HKSOX-1m (5/6-mixture) hydrobromide is a O₂ fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O₂ over a broad range of pH, strong oxidants, and abundant reductants found in cells .

HY-D1156

HKSOX-1m (5/6-mixture)	Reactive Oxygen Species Fluorescent Dye	Others
HKSOX-1m (5/6-mixture) is a O₂ fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O₂ over a broad range of pH, strong oxidants, and abundant reductants found in cells .

HY-143285

AMC-GlcNAc	Fluorescent Dye	Infection
AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .

HY-150175

HKSOX-1	Fluorescent Dye	Inflammation/Immunology
HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O₂ ^•−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O₂ ^•−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O₂ ^•− roles in inflammation, mitochondrial stress, and other physiological processes .

Cat. No.	Product Name	Type

HY-D1591

BODIPY R6G methyl ester	Fluorescent Dyes/Probes
BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .

BODIPY R6G methyl ester

Fluorescent Dyes/Probes

BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .

HY-130027

HKOCl-4 1 Publications Verification BXY2142	Fluorescent Dyes/Probes
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. E_x: 530 nm; E_m 557 nm.

HY-D1156A

HKSOX-1m (5/6-mixture) hydrobromide 1 Publications Verification	Fluorescent Dyes/Probes
HKSOX-1m (5/6-mixture) hydrobromide is a O₂ fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O₂ over a broad range of pH, strong oxidants, and abundant reductants found in cells .

HY-D1156

HKSOX-1m (5/6-mixture)	Fluorescent Dyes/Probes
HKSOX-1m (5/6-mixture) is a O₂ fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O₂ over a broad range of pH, strong oxidants, and abundant reductants found in cells .

HY-143285

AMC-GlcNAc	Fluorescent Dyes/Probes
AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .

AMC-GlcNAc

Fluorescent Dyes/Probes

AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .

Cat. No.	Product Name	Type

HY-W440988

DOPE-mPEG, MW 2000	Drug Delivery
DOPE-mPEG, MW 2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG, MW 2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .

Cat. No.	Product Name		Classification

HY-W440988

DOPE-mPEG, MW 2000		Pegylated Lipids
DOPE-mPEG, MW 2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG, MW 2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .

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