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peroxisomal

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (6)
By Research Areas:	Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (1)

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Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Urate oxidase, Microorganism Uox	Endogenous Metabolite	Others
Urate oxidase, Microorganism (Uox), i.e., uricase, is often used in biochemical studies. Urate oxidase is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals .

L-Pipecolic acid 1 Publications Verification H-HoPro-OH	Endogenous Metabolite	Metabolic Disease
L-Pipecolic acid (H-HoPro-OH) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.

Sultosilic acid piperazine salt Piperazine sultosylate; A-585	Others	Metabolic Disease
Sultosilic acid piperazine salt (Piperazine sultosylate; A-585) is a lipid-lowering agent. Sultosilic acid piperazine salt modifies the blood lipids levels, reduces platelet adhesiveness without promoting peroxisomal activity of hepatocytes or producing other adverse side-effects .

Lignoceric acid Tetracosanoic acid	Endogenous Metabolite	Neurological Disease
Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research .

Acyl-CoA oxidase ACO	Others	Others
Acyl-CoA oxidase (ACO) catalyses the first and rate-determining step of the peroxisomal beta-oxidation of fatty acids and a major producer of hydrogen peroxide (H₂O₂) .

Tetranor-12(S)-HETE	Endogenous Metabolite	Inflammation/Immunology
Tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE (HY-124404A) in numerous tissues. 12(S)‐HETE to tetranor‐12(S)‐HETE conversion could be a marker for psoriasis .

Indole-3-butyric acid 1 Publications Verification Indolebutyric acid	Endogenous Metabolite	Others
Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .

RG-7152	Others	Others
RG-7152 is a tetrazolyl-substituted leukotriene D4 receptor antagonist that can induce peroxisomal β-oxidation and peroxisome bifunctional enzymes (PBEs) in hepatocytes in various animal models. It has been shown to significantly increase PBE levels and β-oxidation activity in rat and mouse liver homogenates, while smaller effects were observed in guinea pigs and monkeys and no effect in dogs. In vitro studies have also shown that it can induce PBEs comparable to clofibric acid, indicating its potential as a peroxisome proliferator .

Trihydroxycholestanoic acid Coprocholic acid	Endogenous Metabolite	Inflammation/Immunology
Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease .

Cat. No.	Product Name	Type

Indole-3-butyric acid 1 Publications Verification Indolebutyric acid	Biochemical Assay Reagents
Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .

Species:	Human (7)
Tag:	His (4) Tag Free (1) GST (1) Fc (1)
Source:	HEK293 (2) Sf9 insect cells (3) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

	ACOX1 Protein, Human (sf9, His) peroxisomal acyl-coenzyme A oxidase 1; AOX; SCOX; ACOX1	Human	Sf9 insect cells
	The ACOX1 protein is critical in the initial steps of peroxisomal β-oxidation, especially of very long-chain fatty acids. It catalyzes the desaturation of fatty acyl-CoA (such as palmitoyl-CoA) to 2-trans-enoyl-CoA. ACOX1 Protein, Human (sf9, His) is the recombinant human-derived ACOX1 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of ACOX1 Protein, Human (sf9, His) is 660 a.a., with molecular weight of ~60 kDa.

	PRDX5/Peroxiredoxin-5 Protein, Human (HEK293, His) Peroxiredoxin-5; PRDX5; Alu corepressor 1; Antioxidant enzyme B166; AOEB166; Liver tissue 2D-page spot 71B; PLP; Peroxiredoxin V; Prx-V; peroxisomal antioxidant enzyme; TPx type VI; Thioredoxin peroxidase PMP20; Thioredoxin reductase	Human	HEK293
	The PRDX5 protein (or Peroxiredoxin-5) plays a critical role as a thiol-specific peroxidase that reduces hydrogen peroxide and organic hydroperoxides. This enzyme activity is essential for cells to defend against oxidative stress and detoxify peroxides. PRDX5/Peroxiredoxin-5 Protein, Human (HEK293, His) is the recombinant human-derived PRDX5/Peroxiredoxin-5 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of PRDX5/Peroxiredoxin-5 Protein, Human (HEK293, His) is 162 a.a., with molecular weight of ~17.0 kDa.

	PEX19 Protein, Human (GST) PEX19; peroxisomal biogenesis factor 19; peroxisomal farnesylated protein , PXF; D1S2223E; HK33; housekeeping gene; 33kD; PMP1; PMPI; PXMP1; peroxin-19; housekeeping gene, 33kD; 33 kDa housekeeping protein; peroxisomal farnesylated protein; PXF; FLJ55296	Human	E. coli
	PEX19 protein is pivotal in early peroxisomal biogenesis, acting as a cytosolic chaperone and import receptor for peroxisomal membrane proteins (PMPs). It binds to and stabilizes newly synthesized PMPs in the cytoplasm, particularly their hydrophobic domains. PEX19 targets PMPs to the peroxisome membrane by associating with integral membrane protein PEX3. Engaging in diverse interactions with peroxisomal membrane proteins and other components, PEX19 facilitates peroxisomal assembly. Additionally, it contributes to nuclear exclusion of CDKN2A, preventing TP53 degradation by MDM2 and interacting with tumor suppressor CDKN2A/p19ARF in intricate cellular processes. PEX19 Protein, Human (GST) is the recombinant human-derived PEX19 protein, expressed by E. coli, with N-GST labeled tag. The total length of PEX19 Protein, Human (GST) is 295 a.a., with molecular weight of 59.3 kDa.

	CROT Protein, Human (V474L, sf9, His) peroxisomal carnitine O-octanoyltransferase; CROT; COT	Human	Sf9 insect cells
	CROT protein is critical in the β-oxidation process, showing the highest enzymatic activity on C6 to C10 substrates. As a key player in lipid metabolism, CROT promotes the conversion of 4,8-dimethylnonanoyl-CoA to its carnitine ester, regulating fatty acid oxidation to achieve cellular energy balance. CROT Protein, Human (V474L, sf9, His) is the recombinant human-derived CROT protein, expressed by Sf9 insect cells , with C-His labeled tag and V474L mutation.

	PEX11A Protein, Human (HEK293, Fc) peroxisomal membrane protein 11A; PMP28; Peroxin-11A; PEX11	Human	HEK293
	The PEX11A protein may regulate peroxisome dynamics, affecting peroxisome proliferation and division by promoting the association of coating proteins with the peroxisomal membrane. PEX11A is associated with structural organization and promotes membrane protrusion and elongation at the peroxisomal surface. PEX11A Protein, Human (HEK293, Fc) is the recombinant human-derived PEX11A protein, expressed by HEK293 , with N-mFc labeled tag. The total length of PEX11A Protein, Human (HEK293, Fc) is 114 a.a., with molecular weight of ~40 KDa.

	PHYH Protein, Human Phytanoyl-CoA dioxygenase, peroxisomal; Phytanic acid oxidase; PhyH; PAHX	Human	E. coli
	PHYH protein catalyzes 2-hydroxylation of various mono-branched and straight-chain acyl-CoA esters, including racemic phytanoyl-CoA and isomers of 3-methylhexadecanoyl-CoA. It acts on acyl-CoAs with a chain length of at least seven carbon atoms, excluding long, very long straight-chain, and 2-methyl or 4-methyl-branched acyl-CoAs. PHYH Protein, Human is the recombinant human-derived PHYH protein, expressed by E. coli , with tag free. The total length of PHYH Protein, Human is 308 a.a., with molecular weight of 32 kDa.

	ACAA1 Protein, Human (sf9, His) 3-ketoacyl-CoA thiolase, peroxisomal; Beta-ketothiolase; ACAA1; ACAA; PTHIO	Human	Sf9 insect cells
	The ACAA1 protein catalyzes the thiolytic cleavage of various straight-chain 3-keto fatty acyl-CoAs, playing a vital role in peroxisomal beta-oxidation of short to very long 3-oxoacyl-CoAs. ACAA1 Protein, Human (sf9, His) is the recombinant human-derived ACAA1 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of ACAA1 Protein, Human (sf9, His) is 398 a.a., with molecular weight of ~43.8 kDa.

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