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Results for "

polyol ester

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldose Reductase (2) Apoptosis (1) Atg7 (1) Atg8/LC3 (1) Autophagy (2) Bacterial (2) Biochemical Assay Reagents (3) Endogenous Metabolite (8) GLP Receptor (1) Insecticide (2) Isotope-Labeled Compounds (3) Lactate Dehydrogenase (2) Parasite (2)
By Research Areas:	Cancer (4) Infection (2) Metabolic Disease (15) Neurological Disease (6)
Oligonucleotides:	Solvents (1) Fillers (1) Emulsifiers (1) Surfactants (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: CETP Carboxylesterase (CES)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3686

D-Arabitol	Endogenous Metabolite	Neurological Disease Metabolic Disease
D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in human.

HY-N2840

Allitol Allodulcitol	Others	Metabolic Disease Cancer
Allitol is a rare natural polyol that can be used as a sweetener. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS .

HY-N10695

Celangulatin C	Parasite	Infection
Celangulatin C is an insecticidal sesquiterpene polyol ester, that can be isolated from the root bark of Pseudolarix kaempferi. Celangulatin C shows LD₅₀ against Mythimna separata of 280.4 μg/mL .

HY-N10697

Angulatin G Celangulatin E	Parasite	Infection
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD₅₀ against Mythimna separata of 1656.4 μg/mL .

HY-N10639

(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran	Others	Others
(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran is a sesquiterpene polyol ester. (1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran can be used for the research of various biochemical .

HY-N7939

Celangulin XIX	Insecticide	Others
Celangulin XIX is a insecticidal that can be isolated from Celastrus angulatu. Celangulin XIX has strong insecticidal activity against Mythimna separate with an ED₅₀ of 73.3 μg/g .

HY-E70398

Sorbitol dehydrogenase L-Iditol dehydrogenase; polyol dehydrogenase; SDH	Biochemical Assay Reagents	Others
Sorbitol dehydrogenase is an oxidoreductase. Sorbitol dehydrogenase can be used as a marker for drug-induced liver injury .

HY-N7871

Angulatin K	Others	Others
Angulatin K is a natural sesquiterpene polyol ester found in the root bark of Celastrus angulatus .

HY-N0538R

Xylitol (Standard)	Autophagy Endogenous Metabolite Bacterial	Cancer
Xylitol (Standard) is the analytical standard of Xylitol. This product is intended for research and analytical applications. Xylitol can be classified as polyols and sugar alcohols.

HY-P2725

Glycerol dehydrogenase	Endogenous Metabolite	Metabolic Disease
Glycerol dehydrogenase is a polyol dehydrogenase that catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone. Glycerol dehydrogenase can be used for glycerol metabolism in diverse microorganisms .

HY-50289

Sorbinil 2 Publications Verification	Aldose Reductase	Metabolic Disease
Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway.

HY-N3686S

D-Arabitol-13C	Endogenous Metabolite	Neurological Disease Metabolic Disease
D-Arabitol- ¹³C is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-N3686R

D-Arabitol (Standard)	Endogenous Metabolite	Neurological Disease Metabolic Disease
D-Arabitol (Standard) is the analytical standard of D-Arabitol. This product is intended for research and analytical applications. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in human.

HY-N3686S1

D-Arabitol-13C-1	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
D-Arabitol- ¹³C-1 is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-N3686S2

D-Arabitol-13C-2	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
D-Arabitol- ¹³C-2 is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-131542

APPA	Aldose Reductase Apoptosis	Metabolic Disease
APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research .

HY-N2840S

Allitol-13C Allodulcitol-¹³C	Isotope-Labeled Compounds	Metabolic Disease Cancer
Allitol- ¹³C is the ¹³C labeled Allitol. Allitol is a rare natural polyol that can be used as a sweetener. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS[1]

HY-N12130

Celangulatin D	Insecticide	Others
Celangulatin D (Compound 2) is an insecticidal sesquiterpene polyol ester isolated from the root bark of the natural Celastrus angulatus. Celangulatin D has insecticidal activity against armyworms. Celangulatin D can be used for insecticidal and anti-tumor research .

HY-107799

Castor oil 2 Publications Verification	Biochemical Assay Reagents	Others
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-N12657

Retinestatin	Others	Neurological Disease
Retinestatin, a new polyol polyketide, can protect SH-SY5Y dopaminergic cells from MPP ⁺ (HY-W008719)-induced cytotoxicity. Retinestatin shows neuroprotective effects in an in vitro model of Parkinson’s disease .

HY-N7393

Isomalt Palatinitol	Lactate Dehydrogenase	Metabolic Disease
Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes .

HY-N7393R

Isomalt (Standard)	Lactate Dehydrogenase	Metabolic Disease
Isomalt (Standard) is the analytical standard of Isomalt. This product is intended for research and analytical applications. Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes .

HY-N7426

3-Deoxyglucosone 3-Deoxy-D-glucosone	GLP Receptor	Metabolic Disease
3-Deoxyglucosone (3-Deoxy-D-glucosone) is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs), such as imidazolone, it is the most specific AGE for 3-DG. 3-Deoxyglucosone synergizes with low glucose to potentiate GLP-1 secretion and is considered as a biomarker for diabetes .

HY-N1680

3,7-Dimethyloct-1-ene-3,6,7-triol	Others	Metabolic Disease
3,7-Dimethyloct-1-ene-3,6,7-triol is a class of monoterpenoid polyols. 3, 7-dimethyloct-1-ene-3,6,7-triol has anti-HIV activity. 3, 7-dimethyloct-1-ene-3,6,7-triol can be used to study the isolation method of this drug from natural fruit ofCnidium monnieri .

HY-N1446C

Sorbitan monooleate	Biochemical Assay Reagents	Others
Sorbitan monooleate is a renewable polyol with unique molecular structures for the development and design of bio-based waterborne polyurethane (WPU) with versatility and excellent mechanical properties. Sorbitan monooleate can be used as an excipient, such as nonionic surfactants, emulsifiers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-N0538

Xylitol Xylite	Autophagy Endogenous Metabolite Bacterial Atg7 Atg8/LC3	Metabolic Disease Cancer
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

Cat. No.	Product Name	Type

HY-107799

Castor oil 2 Publications Verification	Co-solvents
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3686

D-Arabitol	Structural Classification Microorganisms Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in human.

HY-N2840

Allitol Allodulcitol	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields Sweeteners Food Research	Others
Allitol is a rare natural polyol that can be used as a sweetener. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS .

HY-N10695

Celangulatin C	Structural Classification Pinaceae Terpenoids Sesquiterpenes Source classification Pseudolarix amabilis (J. Nelson) Rehder Plants	Parasite
Celangulatin C is an insecticidal sesquiterpene polyol ester, that can be isolated from the root bark of Pseudolarix kaempferi. Celangulatin C shows LD₅₀ against Mythimna separata of 280.4 μg/mL .

HY-N10697

Angulatin G Celangulatin E	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Parasite
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD₅₀ against Mythimna separata of 1656.4 μg/mL .

HY-N7939

Celangulin XIX	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Insecticide
Celangulin XIX is a insecticidal that can be isolated from Celastrus angulatu. Celangulin XIX has strong insecticidal activity against Mythimna separate with an ED₅₀ of 73.3 μg/g .

HY-N7871

Angulatin K	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Others
Angulatin K is a natural sesquiterpene polyol ester found in the root bark of Celastrus angulatus .

HY-N0538R

Xylitol (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Source classification Plants Endogenous metabolite Saccharides	Autophagy Endogenous Metabolite Bacterial
Xylitol (Standard) is the analytical standard of Xylitol. This product is intended for research and analytical applications. Xylitol can be classified as polyols and sugar alcohols.

HY-N3686R

D-Arabitol (Standard)	Structural Classification Microorganisms Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
D-Arabitol (Standard) is the analytical standard of D-Arabitol. This product is intended for research and analytical applications. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in human.

HY-N12130

Celangulatin D	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Insecticide
Celangulatin D (Compound 2) is an insecticidal sesquiterpene polyol ester isolated from the root bark of the natural Celastrus angulatus. Celangulatin D has insecticidal activity against armyworms. Celangulatin D can be used for insecticidal and anti-tumor research .

HY-N12657

Retinestatin	Structural Classification Natural Products Microorganisms Source classification	Others
Retinestatin, a new polyol polyketide, can protect SH-SY5Y dopaminergic cells from MPP ⁺ (HY-W008719)-induced cytotoxicity. Retinestatin shows neuroprotective effects in an in vitro model of Parkinson’s disease .

HY-N7393

Isomalt Palatinitol	other families Source classification Metabolic Disease Plants Disease Research Fields Saccharides	Lactate Dehydrogenase
Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes .

HY-N7393R

Isomalt (Standard)	other families Source classification Plants Saccharides	Lactate Dehydrogenase
Isomalt (Standard) is the analytical standard of Isomalt. This product is intended for research and analytical applications. Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes .

HY-N7426

3-Deoxyglucosone 3-Deoxy-D-glucosone	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	GLP Receptor
3-Deoxyglucosone (3-Deoxy-D-glucosone) is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs), such as imidazolone, it is the most specific AGE for 3-DG. 3-Deoxyglucosone synergizes with low glucose to potentiate GLP-1 secretion and is considered as a biomarker for diabetes .

HY-N1680

3,7-Dimethyloct-1-ene-3,6,7-triol	Structural Classification Other Monoterpenes Terpenoids Carlina acaulis L. Source classification Plants Umbelliferae	Others
3,7-Dimethyloct-1-ene-3,6,7-triol is a class of monoterpenoid polyols. 3, 7-dimethyloct-1-ene-3,6,7-triol has anti-HIV activity. 3, 7-dimethyloct-1-ene-3,6,7-triol can be used to study the isolation method of this drug from natural fruit ofCnidium monnieri .

HY-N0538

Xylitol Xylite	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Saccharides Monosaccharides Cancer	Autophagy Endogenous Metabolite Bacterial Atg7 Atg8/LC3
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

Cat. No.	Product Name	Chemical Structure

HY-N3686S

D-Arabitol-13C
D-Arabitol- ¹³C is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-N3686S1

D-Arabitol-13C-1
D-Arabitol- ¹³C-1 is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-N3686S2

D-Arabitol-13C-2
D-Arabitol- ¹³C-2 is the ¹³C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].

HY-N2840S

Allitol-13C
Allitol- ¹³C is the ¹³C labeled Allitol. Allitol is a rare natural polyol that can be used as a sweetener. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS[1]

Cat. No.	Product Name		Classification

HY-107799

Castor oil 2 Publications Verification		Solvents
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-N1446C

Sorbitan monooleate		Emulsifiers Surfactants
Sorbitan monooleate is a renewable polyol with unique molecular structures for the development and design of bio-based waterborne polyurethane (WPU) with versatility and excellent mechanical properties. Sorbitan monooleate can be used as an excipient, such as nonionic surfactants, emulsifiers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-N0538

Xylitol Xylite		Fillers
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

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polyol ester

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
Products