Search Result
Results for "
poorly
" in MedChemExpress (MCE) Product Catalog:
31
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-143896
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STING
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Cancer
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STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly .
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- HY-Y1892
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Biochemical Assay Reagents
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Others
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Gelucire 44/14 is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery.
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- HY-17031
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SBE-β-CD
Maximum Cited Publications
104 Publications Verification
Sulfobutylether-β-Cyclodextrin
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Biochemical Assay Reagents
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Others
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SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents .
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- HY-120179
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AAK1
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Neurological Disease
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LP-922761 is a potent, selective and orally active adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50s of 4.8 nM and 7.6 nM in enzyme and cell assays, respectively. LP-922761 also inhibits BMP-2-inducible protein kinase (BIKE) with an IC50 of 24 nM. LP-922761 exhibits no significant activity at cyclin G-associated kinase (GAK), opioid, adrenergic α2 or GABAa receptors .
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- HY-134665
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- HY-13275
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IRAK
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Inflammation/Immunology
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IRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, is poorly active against JNK-1 and JNK-2 with IC50 of 3.801 μM, and >10 μM, respectively.
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- HY-167036
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Biochemical Assay Reagents
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Others
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DMG-PEG-Mal (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DMG-PEG-Mal (MW 2000) can be used in drug delivery research .
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- HY-120179A
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AAK1
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Neurological Disease
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LP-922761 hydrate is a potent, selective and orally active adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50s of 4.8 nM and 7.6 nM in enzyme and cell assays, respectively. LP-922761 hydrate also inhibits BMP-2-inducible protein kinase (BIKE) with an IC50 of 24 nM. LP-922761 hydrate shows less activity at cyclin G-associated kinase (GAK), opioid, adrenergic α2 or GABAa receptors .
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- HY-W440930
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Biochemical Assay Reagents
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Others
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Stearic acid-mPEG (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 1000) can be used in drug delivery research .
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- HY-W440925
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Biochemical Assay Reagents
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Others
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m-PEG-DSPE (sodium) (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 5000) can be used in drug delivery research .
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- HY-W440825
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Biochemical Assay Reagents
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Others
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DSPE-PEG-COOH (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 1000) can be used in drug delivery research .
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- HY-166979
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Biochemical Assay Reagents
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Others
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Stearic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 2000) can be used in drug delivery research .
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- HY-W440932
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Biochemical Assay Reagents
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Others
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Stearic acid-mPEG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 5000) can be used in drug delivery research .
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- HY-W440922
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Biochemical Assay Reagents
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Others
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m-PEG-DSPE (sodium) (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 1000) can be used in drug delivery research .
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- HY-167022
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Biochemical Assay Reagents
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Others
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DSPE-PEG-azide (MW 600) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-azide (MW 600) can be used in drug delivery research .
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- HY-15158A
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- HY-W440894
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Biochemical Assay Reagents
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Others
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DSPE-PEG-DBCO (sodium) (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-DBCO (sodium) (MW 5000) can be used in drug delivery research .
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- HY-W440942
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Biochemical Assay Reagents
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Others
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Pentacosadiynoic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 2000) can be used in drug delivery research .
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- HY-166980
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Biochemical Assay Reagents
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Others
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m-PEG-DPPE (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DPPE (MW 2000) can be used in drug delivery research .
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- HY-167031
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Biochemical Assay Reagents
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Others
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DOPE-PEG-DBCO (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG-DBCO (MW 5000) can be used in drug delivery research .
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- HY-166981
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Biochemical Assay Reagents
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Others
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DSPE-PEG-TCO (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-TCO (MW 2000) can be used in drug delivery research .
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- HY-166807
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Biochemical Assay Reagents
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Others
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Palmitate-PEG-Mal (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Palmitate-PEG-Mal (MW 1000) can be used in drug delivery research .
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- HY-166968
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Biochemical Assay Reagents
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Others
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DSPE-PEG-COOH (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 5000) can be used in drug delivery research .
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- HY-167028
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Biochemical Assay Reagents
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Others
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DSPE-PEG-alkyne (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-alkyne (MW 2000) can be used in drug delivery research .
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- HY-W440943
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Biochemical Assay Reagents
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Others
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Pentacosadiynoic acid-mPEG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 5000) can be used in drug delivery research .
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- HY-15158
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- HY-W440881
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Biochemical Assay Reagents
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Others
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DSPE-PEG-DBCO (sodium) (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-DBCO (sodium) (MW 3400) can be used in drug delivery research .
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- HY-166983
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Biochemical Assay Reagents
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Others
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m-PEG-DMG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DMG (MW 5000) can be used in drug delivery research .
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- HY-166982
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Biochemical Assay Reagents
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Others
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DSPE-PEG-PA (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-PA (MW 2000) can be used in drug delivery research .
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- HY-W440941
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Biochemical Assay Reagents
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Others
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Pentacosadiynoic acid-mPEG (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 1000) can be used in drug delivery research .
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- HY-W440830
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Biochemical Assay Reagents
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Others
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DSPE-PEG-COOH (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 3400) can be used in drug delivery research .
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- HY-W440924
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Biochemical Assay Reagents
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Others
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m-PEG-DSPE (sodium) (MW 3000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 3000) can be used in drug delivery research .
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- HY-166871
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Biochemical Assay Reagents
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Others
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DSPE-PEG-endo-BCN (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-endo-BCN (MW 5000) can be used in drug delivery research .
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- HY-P4211
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Bacterial
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Infection
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PSM-β is a active peptide , which can be isolated from Staphylococcus epidermidis. PSM-β is an analog of staphylococcal toxins, as well as a termed phenol-soluble modulin. PSM-β has bacteriostatic and poorly hemolytic properties .
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- HY-144308
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Mps1
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Others
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RMS-07 is a covalent Monopolar Spindle Kinase 1 (MPS1/TTK) inhibitor, with an apparent IC50 of 13.1 nM. RMS-07 targets a poorly conserved cysteine in the kinase's hinge region .
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- HY-166874
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Biochemical Assay Reagents
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Others
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DSPE-PEG-endo-BCN (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-endo-BCN (MW 2000) can be used in drug delivery research .
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- HY-108288
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CP 47904
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Beta-lactamase
Antibiotic
Bacterial
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Infection
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Sulbactam pivoxil is a proagent of sulbactam. Sulbactam is a β-lactamase inhibitor which poorly adsorbed from gastrointestinal tract. Sulbactam pivoxil has a better absorption than the parent agent and provides high serum levels after oral administration .
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- HY-B1172
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4-O-β-D-Galactopyranosyl-D-fructose
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Endogenous Metabolite
Bacterial
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Others
Cancer
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Lactulose (4-O-β-D-Galactopyranosyl-D-fructose) is a poorly absorbed sugar that can be used to study constipation and hepatic encephalopathy. The drug generally begins to take effect 8 to 12 hours after administration, but it may take two days to improve constipation.
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- HY-15894A
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Endothelin Receptor
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Cardiovascular Disease
Endocrinology
Cancer
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BQ-788 is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM .
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- HY-166996
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Biochemical Assay Reagents
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Others
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Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine can be used in drug delivery research .
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- HY-P5492
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Delta-lysin
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Bacterial
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Others
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Delta-hemolysin (Delta-lysin), a 26 amino acid peptide, is a hemolytic peptide produced by Staphylococcus. Delta-hemolysin may slightly perturb a membrane or lead to cell lysis. Delta-hemolysin is a model in the study of peptides interacting with membranes. Delta-hemolysin is poorly active against bacteria .
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- HY-P5492A
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Delta-lysin TFA
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Bacterial
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Others
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Delta-hemolysin (Delta-lysin) TFA, a 26 amino acid peptide, is a hemolytic peptide produced by Staphylococcus. Delta-hemolysin TFA may slightly perturb a membrane or lead to cell lysis. Delta-hemolysin TFA is a model in the study of peptides interacting with membranes. Delta-hemolysin TFA is poorly active against bacteria .
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- HY-B1172R
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Endogenous Metabolite
Bacterial
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Others
Cancer
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Lactulose (Standard) is the analytical standard of Lactulose. This product is intended for research and analytical applications. Lactulose (4-O-β-D-Galactopyranosyl-D-fructose) is a poorly absorbed sugar that can be used to study constipation and hepatic encephalopathy. The drug generally begins to take effect 8 to 12 hours after administration, but it may take two days to improve constipation.
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- HY-N7495R
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Endogenous Metabolite
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Metabolic Disease
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Lactulose (Standard) is the analytical standard of Lactulose. This product is intended for research and analytical applications. Lactulose (4-O-β-D-Galactopyranosyl-D-fructose) is a poorly absorbed sugar that can be used to study constipation and hepatic encephalopathy. The drug generally begins to take effect 8 to 12 hours after administration, but it may take two days to improve constipation.
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- HY-114141
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Prostaglandin Receptor
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Inflammation/Immunology
Endocrinology
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BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively . BI-671800 has potential for the treatment of poorly controlled asthma .
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- HY-152205
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Myosin
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Others
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JB061 is a nonmuscle myosin inhibitor with IC50s of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle myosin), and >100 μM (Smooth muscle myosin II), respectively. JB061 poorly decreases ATPase activity (IC50>200 μM). JB061 shows cytotoxicity against COS-7 cells with an IC50 value of 39 μM .
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- HY-137234
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2,6-Di-O-methyl-β-cyclodextrin
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Biochemical Assay Reagents
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Others
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DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.
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- HY-W250168
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Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10
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Biochemical Assay Reagents
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Others
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Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.
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- HY-401424
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Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
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Biochemical Assay Reagents
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Others
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Cremophor EL-36 is a nonionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). The functions of Cremophor EL-36 include: 1) affecting pharmacokinetics by encapsulating drugs in micelles, changing drug distribution and clearance; 2) activating the complement system and inducing allergic reactions; 3) binding to lipoproteins and interfering with lipid metabolism. Cremophor EL-36 increases drug solubility through micellization, while mediating toxicity through complement activation and lipoprotein interactions .
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HY-L0120V
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170,269 compounds
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“BioDesign” approach incorporates key structural features of known pharmacologically relevant natural products (e.g. alkaloids and other secondary metabolites) into synthetically feasible medicinal chemistry scaffolds. In order to identify the privileged pharmacophores, ring systems and linkers, we have carried out statistical analysis of structural features of natural products, marketed drugs, and drug candidates.
Saturated, fused ring, spiro, and bridged systems with a tendency towards multiple chiral centers are highly privileged among natural products and marketed drugs yet these structures are very poorly represented in commercial libraries. This library addressed this market need by incorporating these privileged elements into the design of novel synthetic molecules with high molecular framework diversity, multiple stereogenic centers (≥2), and degree of saturation (Fsp3 > 0.5).
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HY-L086
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2,733 compounds
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Neurodegenerative diseases are incurable and life-threatening conditions that result in progressive degeneration and/or death of nerve cells. Some common neurodegenerative diseases include Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Motor Neuron Disease (MND), Huntington’s Disease (HD), Spino-Cerebellar Ataxia (SCA), Spinal Muscular Atrophy (SMA), and Amyotrophic Lateral Sclerosis (ALS). Because the pathophysiology of neurodegenerative disorders is generally poorly understood, it is difficult to identify promising molecular targets and validate them. At the same time, about 85% of the drugs fail in clinical trials. Therefore, validating new targets and discovering new drugs to mitigate neurodegenerative disorders is need of the hour.
MCE offers a unique collection of 2,733 compounds with anti-Neurodegenerative Diseases activities or targeting the unique targets of neurodegenerative diseases. MCE Neurodegenerative Disease-related Compound Library is a useful tool for exploring the mechanism of neurodegenerative diseases and discovering new drugs for neurodegenerative diseases.
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| Cat. No. |
Product Name |
Type |
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- HY-Y1892
-
|
|
Co-solvents
|
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Gelucire 44/14 is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery.
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-
- HY-17031
-
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Sulfobutylether-β-Cyclodextrin
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Co-solvents
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SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents .
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- HY-167036
-
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Drug Delivery
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DMG-PEG-Mal (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DMG-PEG-Mal (MW 2000) can be used in drug delivery research .
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- HY-W440930
-
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Drug Delivery
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Stearic acid-mPEG (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 1000) can be used in drug delivery research .
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- HY-W440925
-
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Drug Delivery
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m-PEG-DSPE (sodium) (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 5000) can be used in drug delivery research .
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- HY-W440825
-
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Drug Delivery
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DSPE-PEG-COOH (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 1000) can be used in drug delivery research .
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- HY-166979
-
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Drug Delivery
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Stearic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 2000) can be used in drug delivery research .
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- HY-W440932
-
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Drug Delivery
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Stearic acid-mPEG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 5000) can be used in drug delivery research .
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- HY-W440922
-
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Drug Delivery
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m-PEG-DSPE (sodium) (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 1000) can be used in drug delivery research .
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- HY-167022
-
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Drug Delivery
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DSPE-PEG-azide (MW 600) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-azide (MW 600) can be used in drug delivery research .
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- HY-W440894
-
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Drug Delivery
|
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DSPE-PEG-DBCO (sodium) (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-DBCO (sodium) (MW 5000) can be used in drug delivery research .
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- HY-W440942
-
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Drug Delivery
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Pentacosadiynoic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 2000) can be used in drug delivery research .
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- HY-166980
-
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Drug Delivery
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m-PEG-DPPE (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DPPE (MW 2000) can be used in drug delivery research .
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- HY-167031
-
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Drug Delivery
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DOPE-PEG-DBCO (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG-DBCO (MW 5000) can be used in drug delivery research .
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- HY-166981
-
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Drug Delivery
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DSPE-PEG-TCO (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-TCO (MW 2000) can be used in drug delivery research .
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- HY-166807
-
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Drug Delivery
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Palmitate-PEG-Mal (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Palmitate-PEG-Mal (MW 1000) can be used in drug delivery research .
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- HY-166968
-
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Drug Delivery
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DSPE-PEG-COOH (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 5000) can be used in drug delivery research .
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- HY-167028
-
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Drug Delivery
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DSPE-PEG-alkyne (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-alkyne (MW 2000) can be used in drug delivery research .
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- HY-W440943
-
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Drug Delivery
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Pentacosadiynoic acid-mPEG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 5000) can be used in drug delivery research .
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- HY-W440881
-
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Drug Delivery
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DSPE-PEG-DBCO (sodium) (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-DBCO (sodium) (MW 3400) can be used in drug delivery research .
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-
- HY-166983
-
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Drug Delivery
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m-PEG-DMG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DMG (MW 5000) can be used in drug delivery research .
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-
- HY-166982
-
|
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Drug Delivery
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DSPE-PEG-PA (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-PA (MW 2000) can be used in drug delivery research .
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-
- HY-W440941
-
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Drug Delivery
|
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Pentacosadiynoic acid-mPEG (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 1000) can be used in drug delivery research .
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-
- HY-W440830
-
|
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Drug Delivery
|
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DSPE-PEG-COOH (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 3400) can be used in drug delivery research .
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-
- HY-W440924
-
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Drug Delivery
|
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m-PEG-DSPE (sodium) (MW 3000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 3000) can be used in drug delivery research .
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- HY-166871
-
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Drug Delivery
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DSPE-PEG-endo-BCN (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-endo-BCN (MW 5000) can be used in drug delivery research .
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- HY-166874
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Drug Delivery
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DSPE-PEG-endo-BCN (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-endo-BCN (MW 2000) can be used in drug delivery research .
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- HY-166996
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Drug Delivery
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Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine can be used in drug delivery research .
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- HY-137234
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2,6-Di-O-methyl-β-cyclodextrin
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Co-solvents
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DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.
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- HY-W250168
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Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10
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Surfactants
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Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.
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- HY-401424
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Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
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Biochemical Assay Reagents
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Cremophor EL-36 is a nonionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). The functions of Cremophor EL-36 include: 1) affecting pharmacokinetics by encapsulating drugs in micelles, changing drug distribution and clearance; 2) activating the complement system and inducing allergic reactions; 3) binding to lipoproteins and interfering with lipid metabolism. Cremophor EL-36 increases drug solubility through micellization, while mediating toxicity through complement activation and lipoprotein interactions .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P4211
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Bacterial
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Infection
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PSM-β is a active peptide , which can be isolated from Staphylococcus epidermidis. PSM-β is an analog of staphylococcal toxins, as well as a termed phenol-soluble modulin. PSM-β has bacteriostatic and poorly hemolytic properties .
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- HY-P5492
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Delta-lysin
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Bacterial
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Others
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Delta-hemolysin (Delta-lysin), a 26 amino acid peptide, is a hemolytic peptide produced by Staphylococcus. Delta-hemolysin may slightly perturb a membrane or lead to cell lysis. Delta-hemolysin is a model in the study of peptides interacting with membranes. Delta-hemolysin is poorly active against bacteria .
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- HY-P5492A
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Delta-lysin TFA
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Bacterial
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Others
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Delta-hemolysin (Delta-lysin) TFA, a 26 amino acid peptide, is a hemolytic peptide produced by Staphylococcus. Delta-hemolysin TFA may slightly perturb a membrane or lead to cell lysis. Delta-hemolysin TFA is a model in the study of peptides interacting with membranes. Delta-hemolysin TFA is poorly active against bacteria .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
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Classification |
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- HY-167022
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Azide
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DSPE-PEG-azide (MW 600) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-azide (MW 600) can be used in drug delivery research .
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