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Results for "

protoporphyrin

" in MedChemExpress (MCE) Product Catalog:

25

Inhibitors & Agonists

2

Biochemical Assay Reagents

5

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1247
    Protoporphyrin IX
    10+ Cited Publications

    		 Endogenous Metabolite Others
    Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX
  • HY-W250116
    Co(III) protoporphyrin IX chloride

    protoporphyrin IX cobaltic chloride

    		 Biochemical Assay Reagents Others
    Co(III) Protoporphyrin IX chloride (CoPP) is an effective HO-1inducer.
    Co(III) protoporphyrin IX chloride
  • HY-101193
    Zinc Protoporphyrin
    Maximum Cited Publications
    40 Publications Verification

    Zn(II)-protoporphyrin IX; ZnPP; Zinc protoporphyrin-9

    		 Reactive Oxygen Species Endogenous Metabolite Apoptosis Cardiovascular Disease Metabolic Disease Cancer
    Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .
    Zinc Protoporphyrin
  • HY-101194
    Tin protoporphyrin IX dichloride
    15+ Cited Publications

    Tin-protoporphyrin IX; Sn-protoporphyrin; SnPPIX

    		 Reactive Oxygen Species Cancer
    Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model .
    Tin protoporphyrin IX dichloride
  • HY-136476G
    Pt(II) protoporphyrin IX

    		Others Others
    Pt(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Pt(II) protoporphyrin IX
  • HY-B1247R
    Protoporphyrin IX (Standard)

    		Endogenous Metabolite Others
    Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX (Standard)
  • HY-B1247A
    Protoporphyrin IX disodium

    		Endogenous Metabolite Cancer
    Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX disodium
  • HY-136476E
    Cr(III) protoporphyrin IX

    		Others Others
    Cr(III) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Cr(III) protoporphyrin IX
  • HY-136476F
    Cd(II) protoporphyrin IX

    		Drug Intermediate Others
    Cd(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Cd(II) protoporphyrin IX
  • HY-136476
    Mg(II) protoporphyrin IX

    		Others Others
    Mg(II) protoporphyrin IX is a precursor of chlorophyll in Chlorella. Mg(II) protoporphyrin IX is a negative effector of nuclear photosynthetic gene expression. Mg(II) protoporphyrin IX can be used for the research of signaling molecule implicated in plastid-to-nucleus communication .
    Mg(II) protoporphyrin IX
  • HY-136476A
    Mn(II) protoporphyrin IX

    		Biochemical Assay Reagents Others
    Mn(II) protoporphyrin IX is a potential intravenous paramagnetic magnetic resonance contrast agent. Mn(II) protoporphyrin IX maintains strong paramagnetic properties .
    Mn(II) protoporphyrin IX
  • HY-W854721
    Mn(III) Protoporphyrin IX chloride

    Manganese(III) protoporphyrin IX Chloride

    		 Others Metabolic Disease
    Mn(III) protoporphyrin IX chloride is a metalloporphyrin. It induces mRNA expression of the genes encoding δ-aminolevulinate synthase and heme oxygenase (HO), enzymes that catalyze the rate-limiting steps of heme biosynthesis and degradation, respectively, in chick embryo liver cells when used at a concentration of 10 μM. Mn(III) protoporphyrin IX chloride-containing nanobialys have been used in magnetic resonance imaging (MRI) of fibrin clots in vitro. It has also been used in the synthesis of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histidine methyl ester (MnGGH), a metalloporphyrin conjugate with microperoxidase activity.
    Mn(III) Protoporphyrin IX chloride
  • HY-101193S
    Zinc Protoporphyrin-d2,15N2

    Zn(II)-protoporphyrin IX-d2,15N2; ZnPP-d2,15N2; Zinc protoporphyrin-9-d2,15N2

    		 Apoptosis Endogenous Metabolite Reactive Oxygen Species Isotope-Labeled Compounds Cardiovascular Disease Metabolic Disease Cancer
    Zinc Protoporphyrin-d2, 15N2 is 15N and deuterated labeled Zinc Protoporphyrin (HY-101193). Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .
    Zinc Protoporphyrin-d2,15N2
  • HY-136476B
    Cu(II) protoporphyrin IX

    		Others Inflammation/Immunology Cancer
    Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair .
    Cu(II) protoporphyrin IX
  • HY-134608
    Cobalt protoporphyrin IX

    Co-PPIX

    		 Reactive Oxygen Species Influenza Virus Infection
    Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) .
    Cobalt protoporphyrin IX
  • HY-133100
    5-ALA benzyl ester hydrochloride

    Benzyl-ALA hydrochloride

    		 Endogenous Metabolite Cancer
    5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .
    5-ALA benzyl ester hydrochloride
  • HY-W127816
    Cr(III) Protoporphyrin IX chloride

    		Biochemical Assay Reagents Others
    Cr(III) Protoporphyrin IX Chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Cr(III) Protoporphyrin IX chloride
  • HY-136476C
    Ni(II) protoporphyrin IX

    		Others Others
    Ni(II) protoporphyrin IX is a metalloporphyrin that has a low tendency toward axial ligation, becomes distorted when bound to ferrochelatase .
    Ni(II) protoporphyrin IX
  • HY-135005A
    Biliverdin

    		Endogenous Metabolite Others
    Biliverdin is the product of the oxidation of bilirubin. Biliverdin can be synthesized via a non-protoporphyrin pathway in Corynebacterium glutamicum .
    Biliverdin
  • HY-A0169A
    Methyl aminolevulinate hydrochloride
    1 Publications Verification

    		 Reactive Oxygen Species Inflammation/Immunology Cancer
    Methyl aminolevulinate hydrochloride is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a proagent that can be metabolized to Protoporphyrin IX .
    Methyl aminolevulinate hydrochloride
  • HY-A0169
    Methyl aminolevulinate

    		Reactive Oxygen Species Inflammation/Immunology Cancer
    Methyl aminolevulinate is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a proagent that can be metabolized to Protoporphyrin IX .
    Methyl aminolevulinate
  • HY-128075
    Acifluorfen

    		Herbicide Cancer
    Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species .
    Acifluorfen
  • HY-118985
    Acifluorfen sodium

    		Endogenous Metabolite Cancer
    Acifluorfen sodium, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen sodium causes strong photooxidative destruction of pigments and lipids in sensitive plant species .
    Acifluorfen sodium
  • HY-128075R
    Acifluorfen (Standard)

    		Herbicide Cancer
    Acifluorfen (Standard) is the analytical standard of Acifluorfen. This product is intended for research and analytical applications. Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species .
    Acifluorfen (Standard)
  • HY-161503
    PPO-IN-10

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-10 (Compound 4) is a 2-phenylpyridine derivative of pyrrolidone. PPO-IN-10 inhibits protoporphyrinogen IX oxidase (PPO). PPO-IN-10 leads to the formation of photosensitive protoporphyrin IX and the death of weed leaves. PPO-IN-10 can be used in the research of developing new PPO herbicides .
    PPO-IN-10

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