Search Result
Results for "
triterpenoid saponins
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N12292
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- HY-N12587
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- HY-N8112
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Others
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Others
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Polygalasaponin LII is a triterpenoid saponin that ca n be isolated from the roots of Polygala japonica Houtt .
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- HY-N4064
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Others
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Others
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Hederagenic acid (compound 2) is a kind of triterpenoid saponin. Hederagenic acid can be isolated from the roots of Kalopanax septemlobus (Thunb.) Koidz .
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- HY-N11073
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Others
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Others
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Clematiganoside A is a triterpenoid saponin that can be isolatred from Clematis ganpiniana .
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- HY-N11068
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Others
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Others
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Huzhangoside C is a oleanane-type triterpenoid saponin that can be isolated from the roots of Clematis argentilucida .
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- HY-N12975
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Soyasaponin βg
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Others
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Others
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Chromosaponin I (Soyasaponin βg) is a triterpenoid saponin that can be isolated from pea. Chromosaponin I stimulates the growth of roots in arabidopsis thaliana seedlings .
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- HY-N8609
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Others
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Others
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Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .
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- HY-N11433
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Others
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Others
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Celosin L is a triterpenoid saponin with hepaprotective activity. Celosin L exhibits protective effects against APAP-induced hepatotoxicity in HepG2 cells .
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- HY-N13164
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PI3K
Akt
Apoptosis
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Cancer
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Polygalacin D3 is a triterpenoid saponin compound that can be extracted from the roots of the balloon flower. Polygalacin D3 can inhibit the proliferation of non-small cell lung cancer (NSCLC) cell lines by blocking the PI3K/Akt pathway, and it induces cell cycle arrest and cell apoptosis .
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- HY-N7273
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Apoptosis
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Cancer
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Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells .
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- HY-N12137
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Others
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Cancer
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Glycoside St-J (Compound 2) is a triterpenoid saponin. Glycoside St-J has antitumor activity and inhibits HeLa cell proliferation. Glycoside St-J Isolates from natural Anemone flaccida. Glycoside St-J can be used in the development of new anticancer agents .
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- HY-N0330
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Apoptosis
Autophagy
PI3K
c-Myc
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Metabolic Disease
Inflammation/Immunology
Cancer
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Momordin Ic is an orally active triterpenoid saponin that can be isolated from Kochia scoparia. It is also a SUMO specific protease 1 (SENP1) inhibitor, SENP1/c-MYC signaling pathway inhibitor, and apoptosis inducer. Momordin Ic induces autophagy and apoptosis in liver cancer cells through the PI3K/Akt and MAPK signaling pathways mediated by reactive oxygen species. Momordin Ic has the ability to control glucose induced blood glucose elevation, inhibit gastric emptying, resist rheumatoid arthritis, reduce CCl4 (HY-Y0298) induced hepatotoxicity and anti-tumor activity .
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- HY-N0330R
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Apoptosis
Autophagy
PI3K
c-Myc
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Metabolic Disease
Inflammation/Immunology
Cancer
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Momordin Ic (Standard) is the analytical standard of Momordin Ic. This product is intended for research and analytical applications. Momordin Ic is an orally active triterpenoid saponin that can be isolated from Kochia scoparia. It is also a SUMO specific protease 1 (SENP1) inhibitor, SENP1/c-MYC signaling pathway inhibitor, and apoptosis inducer. Momordin Ic induces autophagy and apoptosis in liver cancer cells through the PI3K/Akt and MAPK signaling pathways mediated by reactive oxygen species. Momordin Ic has the ability to control glucose induced blood glucose elevation, inhibit gastric emptying, resist rheumatoid arthritis, reduce CCl4 (HY-Y0298) induced hepatotoxicity and anti-tumor activity .
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- HY-N9373
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- HY-N6265
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Others
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Others
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Cauloside F is a triterpenoid saponin isolated from Clematis akebioides.
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- HY-N5087
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Others
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Others
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Nudicaucin A is a triterpenoid saponin isolated from Hedyotis nudicaulis .
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- HY-N9989
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Others
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Others
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Brachyoside B is a triterpenoid saponin from Astragalus wiedemannianus .
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- HY-N0206
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Deglucocyclamin; LTS-4; Saxifragifolin B
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Antibiotic
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Cancer
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Ardisiacrispin A (Deglucocyclamin) is a common triterpenoid saponin from Ardisia species. Ardisiacrispin A has similar biological properties with some triterpenoid saponins in A. crenata which is one of the species of genus Ardisia and exhibits cytotoxic effect on tumor cells, immunomodulatory and antiviral activities .
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- HY-N2606
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- HY-107314
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Others
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Others
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Pulchinenoside B is a triterpenoid saponin isolated from Pulsatilla chinensis .
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- HY-N5071
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Others
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Others
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Clematichinenoside C is one of triterpenoid saponins found in Clematis parviloba .
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- HY-107309
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Others
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Cancer
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Scabioside C is a main triterpenoid saponin for total secondary saponin (TSS). TSS, from A. raddeana, exhibits the potential anti-breast cancer effect .
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- HY-N4135
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Others
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Metabolic Disease
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Acanthopanaxoside B is a triterpenoid saponin isolated from the leaves of Acanthopanax senticosus .
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- HY-107235
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Clematoside S; Prosapogenin CP6
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Others
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Others
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Saponin CP6 is a triterpenoid compound from the roots of Clematis grata .
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- HY-N1479
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Others
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Others
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Polygalic acid, a triterpenoid saponin, is considered one of the major active constituents of Polygala tenuifolia .
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- HY-N3520
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- HY-N2001
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- HY-N6970
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Congmunoside V
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Others
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Metabolic Disease
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Araloside V (Congmunoside V) is a triterpenoid saponin isolated from Aralia elata .
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- HY-N7919
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Others
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Metabolic Disease
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Celosin H is a hepatoprotective triterpenoid saponin that can be isolated from Celosiae Semen .
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- HY-N12578
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Others
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Others
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Polygalasaponin XXVIII is a triterpenoid saponin that can be isolated from Polygala japonica Houtt. .
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- HY-N0588
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HCV
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Infection
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Deapioplatycodin D is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
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- HY-N11810
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Others
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Others
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Polyfuroside is a triterpenoid saponin, which can be isolated from the defatted rhizome of jade bamboo .
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- HY-N13217
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Others
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Others
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Black Cohosh Extract is the extract of Black Cohosh, with content of 2.5% , 5% Triterpenoid saponins.
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- HY-N10414
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Primulasaponin 1; Primula acid I
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Others
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Others
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Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid) .
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- HY-N3519
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HCV
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Infection
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Platycodin D3 is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
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- HY-N6088
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Others
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Others
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Isoginsenoside-Rh3 is a triterpenoid saponin from the fruits of Panax ginseng C. A. Mey .
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- HY-N11452
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Others
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Others
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Cernuoside B is a natural triterpenoid saponin that can be isolated from the roots of Pulsatilla koreana Nakai .
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- HY-N0818
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Calenduloside F
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Others
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Others
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Chikusetsusaponin IVa a major active ingredient of triterpenoid saponins, exerts antithrombotic effects, including minor hemorrhagic events.
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- HY-N0204
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Anemoside A3
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iGluR
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Others
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Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice.
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- HY-N8496
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Others
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Others
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Clinopodiside A, a triterpenoid saponin, is isolated from Clinopodium polycephalum which is a popular Chinese traditional medicinal herb .
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- HY-N2542
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- HY-N8410
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Others
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Others
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Momordicoside P is a cucurbitane-type triterpenoid saponin. Momordicoside P can be isolated from the fresh fruits of Momordica charantia .
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- HY-N0891
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Tubeimoside-B
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Others
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Cancer
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Tubeimoside II (Tubeimoside-B) is a natural analogue of oleanane type of triterpenoid saponin; show anti-inflammatory, antitumor, and antitumor-promoting effects.
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- HY-N1433
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Bacterial
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Infection
Inflammation/Immunology
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Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicity
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- HY-N9319
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Decaisoside E
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Others
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Others
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Fulvotomentoside A (Decaisoside E) is a triterpenoid saponin compound isolated from the flowers of Lonicera fulvotomentosa Hsu et S.C. Cheng .
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- HY-N3521
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Deapi-platycoside E
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Others
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Others
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Platycoside G1, a natural product found in Platycodon grandiflorum, is a triterpenoid saponin. Platycoside G1 has potent antioxidant activities .
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- HY-N2601
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Others
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Inflammation/Immunology
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Bayogenin 3-O-β-D-glucopyranoside, a triterpenoid saponin isolated from Polygala japonica, possesses anti-inflammatory activities .
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- HY-N0556
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HIV Protease
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Infection
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Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity .
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- HY-N4215
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Others
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Inflammation/Immunology
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11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity .
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- HY-N5040
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Others
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Inflammation/Immunology
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Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect .
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- HY-N1479R
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Others
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Others
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Polygalic acid (Standard) is the analytical standard of Polygalic acid. This product is intended for research and analytical applications. Polygalic acid, a triterpenoid saponin, is considered one of the major active constituents of Polygala tenuifolia .
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- HY-N6049
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- HY-B2114
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Escin
2 Publications Verification
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Apoptosis
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Metabolic Disease
Inflammation/Immunology
Cancer
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Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent .
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- HY-N0332
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- HY-N8810
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Others
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Others
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Platycoside M1 is a A-ring lactone triterpenoid saponin that can be isolaoted from the roots of Platycodon grandiflorum. Platycosides are the main active constituents of P. grandiflorus with multiple pharmacological activities .
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- HY-N10414R
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Others
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Others
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Primulic acid I (Standard) is the analytical standard of Primulic acid I. This product is intended for research and analytical applications. Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid) .
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- HY-N8116
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Others
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Others
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Leonloside D is a Hederagenin-derived saponin, composed of a molecule of Hederagenin and 1-3 molecules of rhamnose, glucose, or arabinose .
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- HY-N2169
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Bacterial
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Inflammation/Immunology
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Polygalasaponin V is a triterpenoid saponin isolated from the aerial parts of Polygala japonica. Polygala japonica has been a folk medicine herb used as expectorant, anti-inflammatory, antibacterial and antidepressant agents in the south of China .
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- HY-N1508
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Others
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Inflammation/Immunology
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Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate . Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory .
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- HY-N0819
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Apoptosis
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Cancer
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Raddeanin A is a natural triterpenoid saponin component of Anemone raddeana, with anti-cancer activities. Raddeanin A exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway .
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- HY-N1433R
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Bacterial
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Infection
Inflammation/Immunology
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Phytolaccagenin (Standard) is the analytical standard of Phytolaccagenin. This product is intended for research and analytical applications. Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicity
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- HY-N4253
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Others
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Metabolic Disease
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Kudinoside D is a main natural component of triterpenoid saponin derived from Ilex kudingcha. Kudinoside D suppresses adipogenesis through modulation of the AMPK pathway in 3T3-L1 adipocytes .
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- HY-N13098
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NF-κB
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Inflammation/Immunology
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Elatoside F is a triterpenoid saponin with anti-inflammatory activity. Elatoside F inhibits lipopolysaccharide-induced nitric oxide production and nuclear factor NF-κB activation. Elatoside F can be isolated from Aralia elata in one step.
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- HY-N2190
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- HY-N6252
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Others
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Cancer
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Gypenoside XLVI is one of the major dammarane-type triterpenoid saponins from Gynostamma pentaphallum . Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity .
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- HY-N0556R
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HIV Protease
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Infection
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Isoescin IA (Standard) is the analytical standard of Isoescin IA. This product is intended for research and analytical applications. Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity .
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- HY-N2040
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Bacterial
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Infection
Cancer
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(20R)-Protopanaxadiol is a triterpenoid saponin metabolite of 20(R)-ginsenoside Rg3 in black ginseng. (20R)-Protopanaxadiol exhibits anti-tumor activity and cytotoxicity, and potently inhibits the growth of Helicobacter pylori .
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- HY-N5064R
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Others
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Neurological Disease
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Bacoside A3 (Standard) is the analytical standard of Bacoside A3. This product is intended for research and analytical applications. Bacoside A3, a triterpenoid saponin, is one of the major active constituents in Bacopa monnieri. Bacoside A3 has neuroprotective activity .
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- HY-N12141
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Apoptosis
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Inflammation/Immunology
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Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome .
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- HY-N5064
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Apoptosis
NO Synthase
COX
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Neurological Disease
Inflammation/Immunology
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Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease .
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- HY-N0332R
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Reactive Oxygen Species
Apoptosis
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Inflammation/Immunology
Cancer
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Ziyuglycoside II (Standard) is the analytical standard of Ziyuglycoside II. This product is intended for research and analytical applications. Ziyuglycoside II is a triterpenoid saponin compound extracted from Sanguisorba officinalis L.. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect .
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- HY-N7026
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Others
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Metabolic Disease
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Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice .
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- HY-N1508R
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Others
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Inflammation/Immunology
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Ecliptasaponin A (Standard) is the analytical standard of Ecliptasaponin A. This product is intended for research and analytical applications. Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate . Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory .
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- HY-N0255
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α-Hederin
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Apoptosis
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Others
Cancer
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alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .
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- HY-N0392
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Toll-like Receptor (TLR)
PI3K
Akt
NF-κB
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Inflammation/Immunology
Cancer
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Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .
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- HY-126992
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Others
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Cancer
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Sarasinoside A1 is a triterpenoid saponin that inhibits breast cancer cell invasion and induces re-epithelialization. Sarasinoside A1 activates Rap GTPase and promotes the relocalization of β-catenin and ZO-1 at cell-cell contact points. Sarasinoside A1 also increases intercellular space stability and the formation of cell-cell junctions.
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- HY-N2133
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Others
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Others
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Fallaxsaponin A (compound 5) is a natural product isolated from Polygala root .
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- HY-N0392R
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Toll-like Receptor (TLR)
PI3K
Akt
NF-κB
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Inflammation/Immunology
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Polygalasaponin F (Standard) is the analytical standard of Polygalasaponin F. This product is intended for research and analytical applications. Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .
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- HY-N0255R
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Apoptosis
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Others
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alpha-Hederin (Standard) is the analytical standard of alpha-Hederin. This product is intended for research and analytical applications. alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .
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- HY-N6924
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HIV
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Infection
Metabolic Disease
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Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity .
Zingibroside R1 possesses some anti-HIV-1 activity.
Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM) .
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- HY-N12138
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Glucosidase
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Metabolic Disease
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Flaccidoside III is a flavonoid and triterpenoid isolated from the aerial parts of N. sativa (Ranunculaceae). Flaccidoside III inhibits α-Glucosidase (IC50: 256.7 μM) and has potential antioxidant and antidiabetic activities .
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- HY-N0256
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COX
NF-κB
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Cancer
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Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
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- HY-N6850
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Apoptosis
Pyroptosis
AMPK
Bcl-2 Family
JAK
STAT
Calcium Channel
Interleukin Related
TNF Receptor
SOD
Reactive Oxygen Species
PPAR
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Cardiovascular Disease
Inflammation/Immunology
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Calenduloside E is a pentacyclic triterpenoid saponin that can be extracted from the bark and roots of Aralia ovata, and has anti-inflammatory and anti-apoptotic activities. Calenduloside E alleviates atherosclerosis by regulating macrophage polarization, improves mitochondrial function by regulating the AMPK-SIRT3 pathway, and alleviates acute liver injury. In addition, Calenduloside E promotes the interaction between L-type calcium channels and Bcl-2 related apoptosis genes, inhibits calcium overload, and alleviates myocardial ischemia/reperfusion injury. Calenduloside E also improves non-alcoholic fatty liver disease by regulating heat shock-dependent pathways, and inhibits ROS mediated JAK1-STAT3 pathways to reduce cellular inflammatory responses .
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