2. Cell Cycle/DNA Damage Cytoskeleton JAK/STAT Signaling Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK
  3. Microtubule/Tubulin JAK
  4. Tubulin/JAK2-IN-1

Tubulin/JAK2-IN-1 (compound 7g) is a dual inhibitor of Janus kinase 2 (JAK2) and microtubule. Tubulin/JAK2-IN-1 has potent antiproliferative activity against the cancer cells.

For research use only. We do not sell to patients.

Tubulin/JAK2-IN-1 Chemical Structure

Tubulin/JAK2-IN-1 Chemical Structure

CAS No. : 2933938-46-4

Size Price Stock Quantity
5 mg USD 450 In-stock
10 mg USD 720 In-stock
25 mg USD 1450 In-stock
50 mg USD 2300 Get quote
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Based on 1 publication(s) in Google Scholar

Tubulin/JAK2-IN-1 Related Antibodies

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Description

Tubulin/JAK2-IN-1 (compound 7g) is a dual inhibitor of Janus kinase 2 (JAK2) and microtubule. Tubulin/JAK2-IN-1 has potent antiproliferative activity against the cancer cells[1].

Molecular Weight

416.43

Formula

C22H20N6O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

COC1=C(OC)C(OC)=CC(C2=NC=CC3=NC(NC4=CC=CC5=C4C=CN5)=NN23)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (240.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4014 mL 12.0068 mL 24.0136 mL
5 mM 0.4803 mL 2.4014 mL 4.8027 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4014 mL 12.0068 mL 24.0136 mL 60.0341 mL
5 mM 0.4803 mL 2.4014 mL 4.8027 mL 12.0068 mL
10 mM 0.2401 mL 1.2007 mL 2.4014 mL 6.0034 mL
15 mM 0.1601 mL 0.8005 mL 1.6009 mL 4.0023 mL
20 mM 0.1201 mL 0.6003 mL 1.2007 mL 3.0017 mL
25 mM 0.0961 mL 0.4803 mL 0.9605 mL 2.4014 mL
30 mM 0.0800 mL 0.4002 mL 0.8005 mL 2.0011 mL
40 mM 0.0600 mL 0.3002 mL 0.6003 mL 1.5009 mL
50 mM 0.0480 mL 0.2401 mL 0.4803 mL 1.2007 mL
60 mM 0.0400 mL 0.2001 mL 0.4002 mL 1.0006 mL
80 mM 0.0300 mL 0.1501 mL 0.3002 mL 0.7504 mL
100 mM 0.0240 mL 0.1201 mL 0.2401 mL 0.6003 mL
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Tubulin/JAK2-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin/JAK2-IN-12933938-46-4Microtubule/TubulinJAKJanus kinaseTubulin/JAK2-IN-1 inhibitorAntitumorInhibitorinhibitorinhibit

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