2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Z-Arg-Arg-βNA acetate

Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Z-Arg-Arg-βNA acetate Chemical Structure

Z-Arg-Arg-βNA acetate Chemical Structure

CAS No. : 2237216-27-0

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Z-Arg-Arg-βNA acetate Related Antibodies

Top Publications Citing Use of Products

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View All Isoforms
Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

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Description

Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins[1].

IC50 & Target

Cathepsin B[1]
Molecular Weight

649.74

Formula

C32H43N9O6
CAS No.
Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (192.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5391 mL 7.6954 mL 15.3908 mL
5 mM 0.3078 mL 1.5391 mL 3.0782 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5391 mL 7.6954 mL 15.3908 mL 38.4769 mL
5 mM 0.3078 mL 1.5391 mL 3.0782 mL 7.6954 mL
10 mM 0.1539 mL 0.7695 mL 1.5391 mL 3.8477 mL
15 mM 0.1026 mL 0.5130 mL 1.0261 mL 2.5651 mL
20 mM 0.0770 mL 0.3848 mL 0.7695 mL 1.9238 mL
25 mM 0.0616 mL 0.3078 mL 0.6156 mL 1.5391 mL
30 mM 0.0513 mL 0.2565 mL 0.5130 mL 1.2826 mL
40 mM 0.0385 mL 0.1924 mL 0.3848 mL 0.9619 mL
50 mM 0.0308 mL 0.1539 mL 0.3078 mL 0.7695 mL
60 mM 0.0257 mL 0.1283 mL 0.2565 mL 0.6413 mL
80 mM 0.0192 mL 0.0962 mL 0.1924 mL 0.4810 mL
100 mM 0.0154 mL 0.0770 mL 0.1539 mL 0.3848 mL
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Z-Arg-Arg-βNA acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Arg-Arg-βNA2237216-27-0CathepsinSensitive dipeptide substrateInhibitorinhibitorinhibit

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