2. Cytoskeleton
  3. Integrin
  4. α7β1 integrin modulator-1

α7β1 integrin modulator-1 is a potent α7β1 integrin modulator. α7β1 integrin modulator-1 has the potential for the research of muscular dystrophy.

For research use only. We do not sell to patients.

α7β1 integrin modulator-1 Chemical Structure

α7β1 integrin modulator-1 Chemical Structure

CAS No. : 849121-82-0

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Based on 1 publication(s) in Google Scholar

α7β1 integrin modulator-1 Related Antibodies

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Description

α7β1 integrin modulator-1 is a potent α7β1 integrin modulator. α7β1 integrin modulator-1 has the potential for the research of muscular dystrophy[1].

IC50 & Target

α7β1[1]
Molecular Weight

475.56

Formula

C23H29N3O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CC1=C(OC)C=CC=C1)NC2=CC(S(=O)(N3CCOCC3)=O)=CC=C2N4CCOCC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (210.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1028 mL 10.5139 mL 21.0278 mL
5 mM 0.4206 mL 2.1028 mL 4.2056 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1028 mL 10.5139 mL 21.0278 mL 52.5696 mL
5 mM 0.4206 mL 2.1028 mL 4.2056 mL 10.5139 mL
10 mM 0.2103 mL 1.0514 mL 2.1028 mL 5.2570 mL
15 mM 0.1402 mL 0.7009 mL 1.4019 mL 3.5046 mL
20 mM 0.1051 mL 0.5257 mL 1.0514 mL 2.6285 mL
25 mM 0.0841 mL 0.4206 mL 0.8411 mL 2.1028 mL
30 mM 0.0701 mL 0.3505 mL 0.7009 mL 1.7523 mL
40 mM 0.0526 mL 0.2628 mL 0.5257 mL 1.3142 mL
50 mM 0.0421 mL 0.2103 mL 0.4206 mL 1.0514 mL
60 mM 0.0350 mL 0.1752 mL 0.3505 mL 0.8762 mL
80 mM 0.0263 mL 0.1314 mL 0.2628 mL 0.6571 mL
100 mM 0.0210 mL 0.1051 mL 0.2103 mL 0.5257 mL
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α7β1 integrin modulator-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α7β1 integrin modulator-1849121-82-0IntegrinInhibitorinhibitorinhibit

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