1-Stearoyl-sn-glycero-3-phosphocholine

Name: 1-Stearoyl-sn-glycero-3-phosphocholine
Brand: MedChemExpress
SKU: HY-125771
Rating: 4.5 (1 reviews)

Cat. No.: HY-125771 Purity: 99.47%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

1-Stearoyl-sn-glycero-3-phosphocholine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

1-Stearoyl-sn-glycero-3-phosphocholine Chemical Structure

CAS No. : 19420-57-6

Size	Price	Stock	Quantity
25 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Stearoyl-sn-glycero-3-phosphocholine:

1-Stearoyl-sn-glycero-3-phosphocholine-d₃₅ Get quote

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Description

1-Stearoyl-sn-glycero-3-phosphocholine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Molecular Weight

523.68

Formula

C₂₆H₅₄NO₇P

CAS No.

19420-57-6

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 25 mg/mL (47.74 mM; Need ultrasonic)

Ethanol : 12.5 mg/mL (23.87 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9096 mL	9.5478 mL	19.0956 mL
5 mM	0.3819 mL	1.9096 mL	3.8191 mL
10 mM	0.1910 mL	0.9548 mL	1.9096 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% EtOH 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.25 mg/mL (2.39 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% EtOH 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1.25 mg/mL (2.39 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% EtOH 90% Corn Oil
Solubility: ≥ 1.25 mg/mL (2.39 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (12.5 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.47%

Select Batch:

Data Sheet (237 KB) SDS (393 KB)

COA (240 KB) HNMR (274 KB) RP-HPLC (218 KB) MS (81 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol / H₂O	1 mM	1.9096 mL	9.5478 mL	19.0956 mL	47.7391 mL
	5 mM	0.3819 mL	1.9096 mL	3.8191 mL	9.5478 mL
	10 mM	0.1910 mL	0.9548 mL	1.9096 mL	4.7739 mL
	15 mM	0.1273 mL	0.6365 mL	1.2730 mL	3.1826 mL
	20 mM	0.0955 mL	0.4774 mL	0.9548 mL	2.3870 mL
H₂O	25 mM	0.0764 mL	0.3819 mL	0.7638 mL	1.9096 mL
	30 mM	0.0637 mL	0.3183 mL	0.6365 mL	1.5913 mL
	40 mM	0.0477 mL	0.2387 mL	0.4774 mL	1.1935 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.