2. Metabolic Enzyme/Protease
  3. Tyrosinase Endogenous Metabolite
  4. 2-Ketoglutaric acid-d4

2-Ketoglutaric acid-d4  (Synonyms: Alpha-Ketoglutaric acid-d4)

Cat. No.: HY-W013636S1 Purity: 93.10%
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2-Ketoglutaric acid-d4 is the deuterium labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].

For research use only. We do not sell to patients.

2-Ketoglutaric acid-d<sub>4</sub> Chemical Structure

2-Ketoglutaric acid-d4 Chemical Structure

CAS No. : 1381759-60-9

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Other Forms of 2-Ketoglutaric acid-d4:

2-Ketoglutaric acid-d4 Related Antibodies

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Description

2-Ketoglutaric acid-d4 is the deuterium labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Ketoglutaric acid-d4 Related Antibodies
Molecular Weight

150.12

Formula

C5H2D4O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C([2H])([2H])C([2H])([2H])C(C(O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 93.10%

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COA (249 KB)

Handling Instructions (2659 KB)
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2-Ketoglutaric acid-d4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Ketoglutaric acid-d41381759-60-9Alpha-Ketoglutaric acid-d4TyrosinaseEndogenous MetaboliteInhibitorinhibitorinhibit

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