2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Tyrosinase Endogenous Metabolite
  4. 2-Ketoglutaric acid-13C2

2-Ketoglutaric acid-13C2  (Synonyms: Alpha-Ketoglutaric acid-13C2)

Cat. No.: HY-W013636S4
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2-Ketoglutaric acid-13C2 is a deuterated labeled 2-Ketoglutaric acid. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM).

For research use only. We do not sell to patients.

2-Ketoglutaric acid-<sup>13</sup>C<sub>2</sub> Chemical Structure

2-Ketoglutaric acid-13C2 Chemical Structure

CAS No. : 123953-28-6

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Other Forms of 2-Ketoglutaric acid-13C2:

2-Ketoglutaric acid-13C2 Related Antibodies

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Description

2-Ketoglutaric acid-13C2 is a deuterated labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning[2].
2-Ketoglutaric acid acts as precursor for the synthesis of amino acids and nucleotides[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Ketoglutaric acid-13C2 Related Antibodies
Molecular Weight

148.08

Formula

C313C2H6O5
CAS No.
SMILES

OC(CC[13C]([13C](O)=O)=O)=O
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2-Ketoglutaric acid-13C2 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Ketoglutaric acid-13C2123953-28-6Alpha-Ketoglutaric acid-13C2Isotope-Labeled CompoundsTyrosinaseEndogenous MetaboliteInhibitorinhibitorinhibit

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