2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite  (Synonyms: N1-Methylpseudouridine CEP)

Cat. No.: HY-154366 Purity: ≥98.0%
COA Handling Instructions

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5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite Chemical Structure

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite Chemical Structure

CAS No. : 875302-45-7

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10 mg USD 240 In-stock
25 mg USD 480 In-stock
50 mg USD 750 In-stock
100 mg USD 1200 In-stock
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Based on 1 publication(s) in Google Scholar

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite Related Antibodies

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Description

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

875.07

Formula

C46H63N4O9PSi
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)N(C(C)C)P(O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](C2=CN(C)C(NC2=O)=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)OCCC#N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (114.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1428 mL 5.7138 mL 11.4277 mL
5 mM 0.2286 mL 1.1428 mL 2.2855 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1428 mL 5.7138 mL 11.4277 mL 28.5691 mL
5 mM 0.2286 mL 1.1428 mL 2.2855 mL 5.7138 mL
10 mM 0.1143 mL 0.5714 mL 1.1428 mL 2.8569 mL
15 mM 0.0762 mL 0.3809 mL 0.7618 mL 1.9046 mL
20 mM 0.0571 mL 0.2857 mL 0.5714 mL 1.4285 mL
25 mM 0.0457 mL 0.2286 mL 0.4571 mL 1.1428 mL
30 mM 0.0381 mL 0.1905 mL 0.3809 mL 0.9523 mL
40 mM 0.0286 mL 0.1428 mL 0.2857 mL 0.7142 mL
50 mM 0.0229 mL 0.1143 mL 0.2286 mL 0.5714 mL
60 mM 0.0190 mL 0.0952 mL 0.1905 mL 0.4762 mL
80 mM 0.0143 mL 0.0714 mL 0.1428 mL 0.3571 mL
100 mM 0.0114 mL 0.0571 mL 0.1143 mL 0.2857 mL
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5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite875302-45-7N1-Methylpseudouridine CEPNucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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