2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. 6PPD

6PPD is a rubber antioxidant that scavenges ozone, forming nitroxyl radicals. 6PPD exposure decreases hatchability, lowered autonomous movement, reduces body length in zebrafish embryos and causes deformities. 6PPD also produces oxidative stress in zebrafish embryos.

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6PPD Chemical Structure

6PPD Chemical Structure

CAS No. : 793-24-8

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Based on 1 publication(s) in Google Scholar

Other Forms of 6PPD:

6PPD Related Antibodies

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Description

6PPD is a rubber antioxidant that scavenges ozone, forming nitroxyl radicals. 6PPD exposure decreases hatchability, lowered autonomous movement, reduces body length in zebrafish embryos and causes deformities. 6PPD also produces oxidative stress in zebrafish embryos[1].

Molecular Weight

268.40

Formula

C18H24N2
CAS No.
Appearance

Solid

Color

Brown to gray

SMILES

CC(C)CC(NC1=CC=C(NC2=CC=CC=C2)C=C1)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (745.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7258 mL 18.6289 mL 37.2578 mL
5 mM 0.7452 mL 3.7258 mL 7.4516 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.44%

COA (243 KB) HNMR (122 KB) LCMS (96 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7258 mL 18.6289 mL 37.2578 mL 93.1446 mL
5 mM 0.7452 mL 3.7258 mL 7.4516 mL 18.6289 mL
10 mM 0.3726 mL 1.8629 mL 3.7258 mL 9.3145 mL
15 mM 0.2484 mL 1.2419 mL 2.4839 mL 6.2096 mL
20 mM 0.1863 mL 0.9314 mL 1.8629 mL 4.6572 mL
25 mM 0.1490 mL 0.7452 mL 1.4903 mL 3.7258 mL
30 mM 0.1242 mL 0.6210 mL 1.2419 mL 3.1048 mL
40 mM 0.0931 mL 0.4657 mL 0.9314 mL 2.3286 mL
50 mM 0.0745 mL 0.3726 mL 0.7452 mL 1.8629 mL
60 mM 0.0621 mL 0.3105 mL 0.6210 mL 1.5524 mL
80 mM 0.0466 mL 0.2329 mL 0.4657 mL 1.1643 mL
100 mM 0.0373 mL 0.1863 mL 0.3726 mL 0.9314 mL
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6PPD Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6PPD793-24-8Reactive Oxygen Speciesubiquitous rubberozonenitroxyl radicalszebrafish embryosInhibitorinhibitorinhibit

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