2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Beperidium iodide

Beperidium iodide  (Synonyms: SX 810)

Cat. No.: HY-100152 Purity: 99.79%
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Beperidium iodide shows a competitive antagonistic effect against acetylcholine receptor with a pA2 of 7.93.

For research use only. We do not sell to patients.

Beperidium iodide Chemical Structure

Beperidium iodide Chemical Structure

CAS No. : 86434-57-3

Size Price Stock Quantity
1 mg USD 156 In-stock
5 mg USD 390 In-stock
10 mg USD 625 In-stock
25 mg USD 1250 In-stock
50 mg USD 2100 In-stock
100 mg   Get quote  
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Beperidium iodide Related Antibodies

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View All mAChR Isoform Specific Products:

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Beperidium iodide shows a competitive antagonistic effect against acetylcholine receptor with a pA2 of 7.93.

IC50 & Target

pA2: 7.93 (Acetylcholine receptor)[1]
Molecular Weight

527.44

Formula

C23H34IN3O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[N+]1(CC)CCC(OC(C(C2=NOC3=C2C=CC=C3)N4CCCCCC4)=O)CC1.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (189.60 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8960 mL 9.4798 mL 18.9595 mL
5 mM 0.3792 mL 1.8960 mL 3.7919 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (4.74 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (4.74 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8960 mL 9.4798 mL 18.9595 mL 47.3988 mL
5 mM 0.3792 mL 1.8960 mL 3.7919 mL 9.4798 mL
10 mM 0.1896 mL 0.9480 mL 1.8960 mL 4.7399 mL
15 mM 0.1264 mL 0.6320 mL 1.2640 mL 3.1599 mL
20 mM 0.0948 mL 0.4740 mL 0.9480 mL 2.3699 mL
25 mM 0.0758 mL 0.3792 mL 0.7584 mL 1.8960 mL
30 mM 0.0632 mL 0.3160 mL 0.6320 mL 1.5800 mL
40 mM 0.0474 mL 0.2370 mL 0.4740 mL 1.1850 mL
50 mM 0.0379 mL 0.1896 mL 0.3792 mL 0.9480 mL
60 mM 0.0316 mL 0.1580 mL 0.3160 mL 0.7900 mL
80 mM 0.0237 mL 0.1185 mL 0.2370 mL 0.5925 mL
100 mM 0.0190 mL 0.0948 mL 0.1896 mL 0.4740 mL
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Beperidium iodide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Beperidium86434-57-3SX 810SX810SX-810mAChRMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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