2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0346A
    (E)-Ethyl p-methoxycinnamate 24393-56-4 99.53%
    (E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic and anti-microbial effects. (E)-Ethyl p-methoxycinnamate inhibits COX-1 and COX-2 in vitro with IC50s of 1.12 and 0.83 μM, respectively.
    (E)-Ethyl p-methoxycinnamate
  • HY-N0492S
    α-Lipoic Acid-d5 1189471-66-6
    α-Lipoic Acid-d5 is the deuterium labeled α-Lipoic Acid. α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4].
    α-Lipoic Acid-d5
  • HY-Y0507S
    DL-Serine-2,3,3-d3 70094-78-9 99.91%
    DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
    DL-Serine-2,3,3-d3
  • HY-131596B
    Emtricitabine triphosphate tetrasodium salt 1188407-46-6 99.06%
    Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However，Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427)，a nucleoside reverse transcriptase inhibitor，targeting to HIV and HBV.
    Emtricitabine triphosphate tetrasodium salt
  • HY-P10208A
    RKH acetate 99.45%
    RKH acetate exerts protective effects against sepsis-induced death and organ damage. RKH acetate can directly bind to Toll-like receptor 4 (TLR4) and block TLR4 signal transduction in immune cells.
    RKH acetate
  • HY-W004282
    Undecanoic acid 112-37-8 ≥98.0%
    Undecanoic acid (Undecanoate) is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
    Undecanoic acid
  • HY-W013441
    2',3'-Dideoxyadenosine 4097-22-7 ≥99.0%
    2',3'-Dideoxyadenosine is an inhibitor of HIV replication. Antiretroviral activity. Antiviral efficacy.
    2',3'-Dideoxyadenosine
  • HY-W014612
    Eugenol acetate 93-28-7 99.76%
    Eugenol acetate (Eugenyl acetate) is an antibacterial, anticancer, anti-inflammatory and antioxidant. Eugenol acetate inhibits NF-κB and enhances the expression of p53 and p21 (WAF1). Eugenol acetate can prevent chemically induced skin cancer, inhibit cancer cell proliferation and induce apoptosis.
    Eugenol acetate
  • HY-W016586
    Acivicin 42228-92-2 ≥98.0%
    Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.
    Acivicin
  • HY-W018397
    Tiliquinol 5541-67-3 ≥98.0%
    Tiliquinol (NSC 130828) is a non-absorbed anti-amoebic luminal agent. Tiliquinol is used in combination with tibroquinol. Tiliquinol can be used for the research of amebic liver abscess.
    Tiliquinol
  • HY-17578
    Pneumocandin B0 135575-42-7
    Pneumocandin B0 (L-688786), the precursor of the antifungal agent Caspofungin acetate, is an antifungal agent belonging to the echinocandin family. Pneumocandin B0, derived from the flamentous fungus Glarea lozoyensis, is a synthetic intermediate of Cancidas.
    Pneumocandin B0
  • HY-Y0493
    HODHBt 28230-32-2 ≥98.0%
    HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer.
    HODHBt
  • HY-12639A
    Bephenium (hydroxynaphthoate) 3818-50-6 99.91%
    Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.
    Bephenium (hydroxynaphthoate)
  • HY-128200
    Pseudomonas quinolone signal 108985-27-9 ≥98.0%
    Pseudomonas Quinolone Signal (Compound C), a signaling molecule produced by Pseudomonas aeruginosa, can activate lasB. Pseudomonas Quinolone Signal can be used in the study of virulence regulation in Pseudomonas aeruginosa.
    Pseudomonas quinolone signal
  • HY-153879
    C12-TLRa ≥99.0%
    C12-TLRa is an adjuvant lipidoid. C12-TLRa acts as a structural component of LNP to enhance mRNA delivery. C12-TLRa substitution can increase antigen-specific antibody responses and B cell responses of clinically relevant mRNA-LNP vaccines.
    C12-TLRa
  • HY-Y0669S
    Pipecolic acid-d9 790612-94-1 99.59%
    Pipecolic acid-d9 is the deuterium labeled Pipecolic acid. Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy.
    Pipecolic acid-d9
  • HY-W054064
    6-Chloro-7-deazapurine-β-D-riboside 16754-80-6
    Chloro-7-deazapurine-β-D-riboside is a nucleoside derivative and has antifungal activity.
    6-Chloro-7-deazapurine-β-D-riboside
  • HY-19748
    LED209 245342-14-7 98.40%
    LED209 is a potent and orally active small molecule inhibitor of the bacterial receptor QseC and a potent prodrug with high selectivity for QseC. LED209 inhibits the binding of signaling molecules to QseC. LED209 has antibacterial activity.
    LED209
  • HY-17506S
    Azithromycin-d3 163921-65-1 ≥98.0%
    Azithromycin-d3 is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].
    Azithromycin-d3
  • HY-14904
    Umifenovir 131707-25-0 98.00%
    Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro. Umifenovir shows anti-inflammatory activity.
    Umifenovir
Cat. No. Product Name / Synonyms Application Reactivity