2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W011500
    TCEP hydrochloride
    		98.71%
    TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry.
    TCEP hydrochloride
  • HY-B0717
    Tocofersolan
    		≥98.0%
    Tocofersolan is synthetic polyethylene glycol derivative of α-tocopherol. Tocofersolan is an orally active and water-soluble analog of vitamin E. Tocofersolan can reduce neurobehavioral deficits in zebrafish embryos exposed to moderate and high concentrations of BaP during early development. Tocofersolan shows antioxidant activity. Tocofersolan can be used to provide an orally bioavailable source of vitamin E.
    Tocofersolan
  • HY-B1829A
    Dexamethasone phosphate disodium
    		99.76%
    Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is an orally active Glucocorticoid receptor agonist.
    Dexamethasone phosphate disodium
  • HY-138193
    Lauryl maltose neopentyl glycol
    		99.96%
    Lauryl maltose neopentyl glycol (LMNG) is a detergent that can solubilize and stabilize membrane proteins. Lauryl maltose neopentyl glycol extracts integral membrane proteins from membranes, and improves substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes.
    Lauryl maltose neopentyl glycol
  • HY-129389
    Benzyl-α-GalNAc
    		Inhibitor 99.95%
    Benzyl-α-GalNAc is a potent O-glycosylation inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-FU (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation.
    Benzyl-α-GalNAc
  • HY-162859
    AB25583
    		99.85%
    AB25583 is a Polθ helicase (Polθ-hel) small molecule inhibitor, with an IC50 value of 6 nM. AB25583 selectively kills BRCA1/2 deficient cells and works in synergy with Olaparib (HY-10162) in cancer cells carrying pathogenic BRCA1/2 mutations. AB25583 can be used for tumor research.
    AB25583
  • HY-164421
    PhpC
    		98.00%
    PhpC is a G-clamp analogue. PhpC shows antiproliferative activity against MCF7 cells, with an IC50 of 387.9 μM. PhpC modulates G-quadruplex-RNA landscapes in human cells.
    PhpC
  • HY-I0635
    (Rac)-Apremilast
    		99.53%
    (Rac)-Apremilast ((Rac)-CC-10004) is the racemic mixture of Apremilast. (Rac)-Apremilast has anti-inflammatory properties and can be used for research on inflammatory diseases, such as psoriasis.
    (Rac)-Apremilast
  • HY-W010342
    6-Aminonicotinamide
    		Inhibitor 99.95%
    6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin, in killing cancer cells.
    6-Aminonicotinamide
  • HY-131442
    Alkyne-phenol
    		Chemical 99.45%
    Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins. Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkyne-phenol
  • HY-108470
    Ro5-3335
    		99.52%
    Ro5-3335, a benzodiazepine, acts as an inhibitor of core binding factor (CBF) leukemia. Ro5-3335 is a RUNX1-CBFβ interaction inhibitor that represses RUNX1/CBFB-dependent transactivation.
    Ro5-3335
  • HY-W187305
    MASM7
    		99.85%
    MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 μM.
    MASM7
  • HY-107410
    SC-26196
    		Inhibitor 99.68%
    SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC50=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties.
    SC-26196
  • HY-112779
    Pertussis Toxin
    		≥99.0%
    Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. Pertussis Toxin inhibits G protein-coupled receptor (GPR) signaling through Gi proteins.
    Pertussis Toxin
  • HY-154919
    DC-Y13-27
    		99.52%
    DC-Y13-27, a derivative of DC-Y13, is a YTHDF2 inhibitor (KD: 37.9 μM). DC-Y13-27 enhances tumor responses to radiotherapy and immunotherapy.
    DC-Y13-27
  • HY-148335
    IRG1-IN-1
    		Inhibitor 99.82%
    IRG1-IN-1 is an itaconic acid derivative. IRG1-IN-1 can inhibit immune-responsive gene 1 (IRG1) activity. IRG1-IN-1 can be used for the research of cancer, inflammation and autoimmune diseases.
    IRG1-IN-1
  • HY-W011845
    DMBA
    		Inducer 99.93%
    DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models.
    DMBA
  • HY-B0564
    Sodium nitroprusside
    		≥99.0%
    Sodium nitroprusside (Ro 21-2498) is a potent vasodilator working through releasing NO spontaneously in blood.
    Sodium nitroprusside
  • HY-123962
    G6PD activator AG1
    		Activator 99.54%
    G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) activator with an EC50 of 3 µΜ. G6PD activator AG1 reduces hemolysis of human erythrocytes.
    G6PD activator AG1
  • HY-W040233
    L-Lactic acid sodium
    		99.82%
    Sodium (S)-2-hydroxypropanoate (Sodium L-lactate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.
    L-Lactic acid sodium
Cat. No. Product Name / Synonyms Application Reactivity