2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W011500
    TCEP hydrochloride
    		98.71%
    TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry.
    TCEP hydrochloride
  • HY-138193
    Lauryl maltose neopentyl glycol
    		99.96%
    Lauryl maltose neopentyl glycol (LMNG) is a detergent that can solubilize and stabilize membrane proteins. Lauryl maltose neopentyl glycol extracts integral membrane proteins from membranes, and improves substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes.
    Lauryl maltose neopentyl glycol
  • HY-W010342
    6-Aminonicotinamide
    		Inhibitor 99.95%
    6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin, in killing cancer cells.
    6-Aminonicotinamide
  • HY-108470
    Ro5-3335
    		99.52%
    Ro5-3335, a benzodiazepine, acts as an inhibitor of core binding factor (CBF) leukemia. Ro5-3335 is a RUNX1-CBFβ interaction inhibitor that represses RUNX1/CBFB-dependent transactivation.
    Ro5-3335
  • HY-154919
    DC-Y13-27
    		99.52%
    DC-Y13-27, a derivative of DC-Y13, is a YTHDF2 inhibitor (KD: 37.9 μM). DC-Y13-27 enhances tumor responses to radiotherapy and immunotherapy.
    DC-Y13-27
  • HY-102013
    Omilancor
    		98.44%
    BT-11 is an orally available LANCL2 binding compound for treating inflammatory bowel disease.
    Omilancor
  • HY-W069604
    Thalidomide-5-Br
    		98.68%
    Thalidomide-5-Br (compound 4) is a compound with a bromodomain. Thalidomide-5-Br can be used in the research of inflammation, tumor and neurology.
    Thalidomide-5-Br
  • HY-168000
    TREX1-IN-2
    TREX1-IN-2 (Compound 15B) is an inhibitor of TREX1 with an IC50 vaule of < 1.00 μM against Human TREX1. TREX1-IN-2 exhibits anticancer activity in vivo.
    TREX1-IN-2
  • HY-W011845
    DMBA
    		Inducer 99.93%
    DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models.
    DMBA
  • HY-11101
    Alendronate sodium hydrate
    		99.6%
    Alendronate (sodium hydrate) is a farnesyl diphosphate synthase inhibitor with IC50 of 460 nM.
    Alendronate sodium hydrate
  • HY-N3025
    Zinc sulfate heptahydrate
    		99.8%
    Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate. Zinc sulfate heptahydrate is a dietary supplement used for zinc deficiency and to prevent the condition in those at high risk.
    Zinc sulfate heptahydrate
  • HY-136151
    UNC10217938A
    		99.41%
    UNC10217938A is a 3-deazapteridine analog with strong oligonucleotide enhancing effects. UNC10217938A enhances oligonucleotides effects by modulating their intracellular trafficking and release from endosomes. UNC10217938A also enhances the effects of antisense and siRNA oligonucleotides.
    UNC10217938A
  • HY-120821
    Endosidin-2
    		Modulator 99.17%
    Endosidin2 (ES2) is an inhibitor of EXO70, and binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis.
    Endosidin-2
  • HY-146064
    OPN expression inhibitor 1
    		Inhibitor
    OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor. OPN expression inhibitor 1 can be used for breast cancer research.
    OPN expression inhibitor 1
  • HY-114231B
    Exaluren disulfate
    		≥98.0%
    Exaluren (ELX-02) disulfate is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). Exaluren disulfate is being developed as a therapy for genetic diseases caused by nonsense mutations.
    Exaluren disulfate
  • HY-108467
    GGsTop
    		Inhibitor 99.35%
    GGsTop (Nahlsgen) is a potent, non-toxic, highly selective and irreversible γ-GGT inhibitor, with a Ki of 170 μM for Human GGT. GGsTop shows a pKa of 9.71, also exhibits Kons of 150 and 51 M-1 s-1 against E.coli GGT and human GGT, respectively. GGsTop protects hepatic ischemia-reperfusion injury in rat model.
    GGsTop
  • HY-139566
    Abrucomstat
    Abrucomstat (3-Nitroxypropanol) is an orally active methyl coenzyme M reductase inhibitor. Abrucomstat decreases ruminal methanogenesis.
    Abrucomstat
  • HY-18630A
    Ro 48-8071 fumarate
    		Inhibitor 99.42%
    Ro 48-8071 fumarate is an inhibitor of OSC (Oxidosqualene cyclase) with IC50 of appr 6.5 nM.
    Ro 48-8071 fumarate
  • HY-B0404A
    Benserazide hydrochloride
    		Inhibitor 99.87%
    Benserazide hydrochloride (Serazide) is commonly used in Parkinson's disease and is an inhibitor of peripheral aromatic L-amino acid decarboxylase (AADC).
    Benserazide hydrochloride
  • HY-110150
    UNC3230
    		99.78%
    UNC3230 is a potent, selective and ATP-competitive PIP5K1C inhibitor with an IC50 of ~41 nM. UNC3230 also inhibits PIP4K2C and does not inhibit any of the other lipid kinases that regulate phosphoinositide levels. UNC3230 has antinociceptive and anticancer effects.
    UNC3230
Cat. No. Product Name / Synonyms Application Reactivity