2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-19609
    Calicheamicin
    		98.28%
    Calicheamicin, an antitumor antibiotic, is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin is a DNA synthesis inhibitor. Calicheamicin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Calicheamicin
  • HY-10052
    Aprepitant
    		99.82%
    Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a Kd of 86 pM.
    Aprepitant
  • HY-10846
    Delamanid
    		99.95%
    Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids.
    Delamanid
  • HY-10844
    Pretomanid
    		99.97%
    Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid
  • HY-15597
    Salinomycin
    		99.66%
    Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin shows selective activity against human cancer stem cells.
    Salinomycin
  • HY-A0256
    Clavulanic acid
    		99.76%
    Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias.
    Clavulanic acid
  • HY-13678A
    Meropenem trihydrate
    		99.92%
    Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL).
    Meropenem trihydrate
  • HY-B0472
    Streptomycin sulfate
    		≥98.0%
    Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
    Streptomycin sulfate
  • HY-16321
    Micafungin sodium
    		98.91%
    Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.
    Micafungin sodium
  • HY-B0329
    Isoniazid
    		99.91%
    Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity.
    Isoniazid
  • HY-B0356A
    Ciprofloxacin monohydrochloride
    		99.90%
    Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin monohydrochloride
  • HY-66011A
    Moxifloxacin
    		99.47%
    Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
    Moxifloxacin
  • HY-B0919
    Azaserine
    		99.96%
    Azazerine (CI-337) is a competitive inhibitor of glutamine amidotransferase. Azaserine is an antibiotic, it shows antibacterial activities. Azazerine shows anti-tumor activities and it may also act as a tumor inducer. Azazerine can be used for the research of cancer and infection.
    Azaserine
  • HY-10882
    Clotrimazole
    		99.91%
    Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.
    Clotrimazole
  • HY-118660
    Anhydrotetracycline hydrochloride
    		99.68%
    Anhydrotetracycline hydrochloride, a tetracycline biosynthetic precursor, is a potent competitive broad-spectrum tetracycline destructase enzymes inhibitor. Anhydrotetracycline hydrochloride is an effector for tetracycline controlled gene expression systems in eukaryotic cells.
    Anhydrotetracycline hydrochloride
  • HY-13553
    Anidulafungin
    		99.69%
    Anidulafungin is a new semisynthetic echinocandin with antifungal potency.
    Anidulafungin
  • HY-B0139
    Flucytosine
    		99.99%
    Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells.
    Flucytosine
  • HY-P1607
    Nisin
    Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. Nisin has antibacterial and anti-inflammatory activity.
    Nisin
  • HY-B0322
    Sulfamethoxazole
    		99.70%
    Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
    Sulfamethoxazole
  • HY-101938
    Sinefungin
    		99.91%
    Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation.
    Sinefungin
Antibiotic Isoform Comparison

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