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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7585):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0351S2
    Taurine-13C2,15N
    98.60%
    Taurine-13C2,15N is the 13C- and 15N- labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].
    Taurine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-W010209S2
    DL-Histidine-d3
    ≥99.0%
    DL-Histidine-d3 is the deuterium labeled DL-Histidine.
    DL-Histidine-d<sub>3</sub>
  • HY-B2176S5
    ATP-15N5 dilithium
    ≥99.0%
    ATP-15N5 (Adenosine 5'-triphosphate-15N5) dilithium is 15N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
    ATP-<sup>15</sup>N<sub>5</sub> dilithium
  • HY-N0100S
    Naringenin-d4
    99.88%
    Naringenin-d4 is the deuterated version of Naringenin (HY-N0100). Naringenin shows strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity[1].
    Naringenin-d<sub>4</sub>
  • HY-B1453S
    L-Carnitine-d3 hydrochloride
    ≥98.0%
    L-Carnitine-d3 (hydrochloride) is the deuterium labeled L-Carnitine hydrochloride[1].
    L-Carnitine-d<sub>3</sub> hydrochloride
  • HY-W017389S
    Xanthine-13C,15N2
    ≥98.0%
    Xanthine-13C,15N2 is a 15N-labeled and 13C-labled Xanthine (HY-W017389). Xanthine is a plant alkaloid with mild stimulant activity of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation.
    Xanthine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-W259489S
    Picolinic acid-d4
    ≥99.0%
    Ppicolinic-3,4,5,6-d4 acid is the deuterium labeled Ppicolinic acid[1].
    Picolinic acid-d<sub>4</sub>
  • HY-76082S
    L-Pyroglutamic acid-d5
    98.6%
    L-Pyroglutamic acid-d5 is the deuterium labeled L-Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.
    L-Pyroglutamic acid-d<sub>5</sub>
  • HY-N0739S1
    Betaine-d9 chloride
    99.66%
    Betaine-d9 (chloride) is the deuterium labeled Betaine chloride[1].
    Betaine-d<sub>9</sub> chloride
  • HY-10219S
    Rapamycin-d3
    Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
    Rapamycin-d<sub>3</sub>
  • HY-42487S
    Exatecan Intermediate 1-d5
    99.90%
    Exatecan Intermediate 1-d5 is the deuterium labeled Exatecan Intermediate 1.
    Exatecan Intermediate 1-d<sub>5</sub>
  • HY-150642S
    Guanosine-5 '- monophosphate-15N5 sodium
    99.50%
    Guanosine-5 '- monophosphate-15N5 (sodium) is the 15N labeled Guanosine-5 '- monophosphate sodium[1].
    Guanosine-5 '- monophosphate-<sup>15</sup>N<sub>5</sub> sodium
  • HY-Y0001S
    Cyclopropanecarboxylic acid-d4
    99.58%
    Cyclopropanecarboxylic acid-d4 is the deuterium labeled Cyclopropylcarboxylic acid[1].
    Cyclopropanecarboxylic acid-d<sub>4</sub>
  • HY-128754S1
    Monoolein-d7
    ≥99.0%
    Monoolein-d7 is deuterium labeled Monoolein. Monoolein is an endogenous metabolite.
    Monoolein-d<sub>7</sub>
  • HY-10162S
    Olaparib-d5
    ≥99.0%
    Olaparib-d5 (AZD2281-d5) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator.
    Olaparib-d<sub>5</sub>
  • HY-B2227BS
    Lactate-d4 sodium
    ≥99.0%
    Lactate-d4 sodium (60% in water) is the deuterium labeled Lactate sodium (60% in water). Lactate sodium (60% in water) is the product of glycogenolysis and glycolysis. Lactate sodium (60% in water) functions in a variety of biochemical processes.
    Lactate-d<sub>4</sub> sodium
  • HY-101037S1
    Sarcosine-d3
    99.05%
    Sarcosine-d3 is the deuterium labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
    Sarcosine-d<sub>3</sub>
  • HY-12678S1
    Entrectinib-d8
    99.82%
    Entrectinib-d8 (NMS-E628-d8; RXDX-101-d8) is a deuterated version of Entrectinib (HY-12678). Entrectinib (NMS-E628) is an orally available, blood-brain barrier permeable, central nervous system active TrkA/B/C, ROS1 and ALK inhibitor with IC50 values of 1, 3, 5, 12 and 12, respectively. 7 nM. Entrectinib induces apoptosis and cycle arrest in cancer cells, has anti-tumor activity, and also alleviates bleomycin-induced pulmonary fibrosis in mice.
    Entrectinib-d<sub>8</sub>
  • HY-N0326S2
    L-Methionine-13C,d3
    99.9%
    L-Methionine-13C,d3 is the 13C- and deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
    L-Methionine-<sup>13</sup>C,d<sub>3</sub>
  • HY-P0014S1
    Liraglutide-13C5,15N TFA
    98.19%
    Liraglutide-13C5,15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
    Liraglutide-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N TFA