Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitor (1)

Isotope-Labeled Compounds Related Products (7596):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-12678S1

Entrectinib-d₈		99.82%
Entrectinib-d8 (NMS-E628-d8; RXDX-101-d8) is a deuterated version of Entrectinib (HY-12678). Entrectinib (NMS-E628) is an orally available, blood-brain barrier permeable, central nervous system active TrkA/B/C, ROS1 and ALK inhibitor with IC₅₀ values of 1, 3, 5, 12 and 12, respectively. 7 nM. Entrectinib induces apoptosis and cycle arrest in cancer cells, has anti-tumor activity, and also alleviates bleomycin-induced pulmonary fibrosis in mice.

HY-N0326S2

L-Methionine-¹³C,d₃		99.9%
L-Methionine-¹³C,d₃ is the ¹³C- and deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

HY-P0014S1

Liraglutide-¹³C₅,¹⁵N TFA		98.19%
Liraglutide-¹³C₅,¹⁵N (tetraTFA) is the ¹³C and ¹⁵N labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

HY-N0667S5

L-Asparagine-d₃ hydrate		99.64%
L-Asparagine-d₃ (hydrate) is the deuterium labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-W454945S

tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d₈		≥99.0%
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled tert-Butyl piperazine-1-carboxylate[1].

HY-B0075S1

Melatonin-d₃		99.81%
Melatonin-d₃ is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress.

HY-B0228S11

Adenosine-¹⁵N₅		99.90%
Adenosine-¹⁵N₅ (Adenine riboside-¹⁵N₅; D-Adenosine-¹⁵N₅) is the ¹⁵N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-143711S

Trimethyllysine-d₉
Trimethyllysine-d₉ is the deuterium labeled Trimethyllysine (HY-143711). Trimethyllysine is an important post-translationally modified amino acid, involving in carnitine biosynthesis and epigenetic processes.

HY-B0421S

Mycophenolic acid-d₃		98.95%
Mycophenolic acid-d₃ is deuterium labeled Mycophenolic acid, which is an an immunosuppresant agent and has potent anti-proliferative activity.

HY-15330

Vitamin D2-d₃		98.60%
Vitamin D2-d₃ (Ergocalciferol-d₃) is the deuterium labeled vitamin D2.

HY-N7148S

α-Vitamin E-d₆		≥99.0%
α-Vitamin E-d₆ is the deuterium labeled α-Vitamin E[1].

HY-B2219S2

Stearic acid-¹³C₁₈		≥98.0%
Stearic acid-¹³C₁₈is the ¹³C-labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-16562S1

Irinotecan-d₁₀ hydrochloride		99.76%
Irinotecan-d₁₀ (hydrochloride) is the deuterium labeled Irinotecan. Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1][2].

HY-70002S1

Enzalutamide-d₆		99.84%
Enzalutamide-d₆ (MDV3100-d₆) is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC₅₀ of 36 nM in LNCaP prostate cells.

HY-133689AS

3-Nitrophenylhydrazine-¹³C₆ hydrochloride		98.26%
3-Nitrophenylhydrazine-¹³C₆ (hydrochloride) is the ¹³C labeled 3-Nitrophenylhydrazine hydrochloride[1].

HY-B0511S

Biotin-d₂-1		99.65%
Biotin-d₂-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-N0390S6

L-Glutamine-¹³C₅,¹⁵N₂		≥98.0%
L-Glutamine-¹³C₅,¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.

HY-132429S

3-Indoxyl Sulfate-d₅ potassium		99.77%
3-Indoxyl Sulfate-d₅ (potassium) is the deuterium labeled 3-Indoxyl Sulfate potassium[1].

HY-W244382

Alanine-2,3,3,3-d4		≥98.0%
Alanine-2,3,3,3-d4 is the deuterium labeled Alanine-2,3,3,3[1].

HY-144243S

Vitamin B5-d₄ calcium		99.51%
Vitamin B5-d₄ (calcium) is the deuterium labeled Vitamin B5 calcium[1].

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