Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitor (1)

Isotope-Labeled Compounds Related Products (7674):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-133689AS

3-Nitrophenylhydrazine-¹³C₆ hydrochloride		98.26%
3-Nitrophenylhydrazine-¹³C₆ (hydrochloride) is the ¹³C labeled 3-Nitrophenylhydrazine hydrochloride[1].

HY-B0511S

Biotin-d₂-1		99.65%
Biotin-d₂-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-132429S

3-Indoxyl Sulfate-d₅ potassium		99.77%
3-Indoxyl Sulfate-d₅ (potassium) is the deuterium labeled 3-Indoxyl Sulfate potassium[1].

HY-18569S2

3-Indoleacetic acid-2,2-d₂		98.06%
3-Indoleacetic acid-2,2-d₂ is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

HY-B2233AS

Calcium phosphorylcholine-d₉ chloride		≥98.0%
Calcium phosphorylcholine-d₉ (chloride) is the deuterium labeled Calcium phosphorylcholine chloride. Calcium phosphorylcholine chloride is the main phospholipid component in eukaryotic biofilms. Calcium phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Calcium phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties.

HY-144243S

Vitamin B5-d₄ calcium		99.51%
Vitamin B5-d₄ (calcium) is the deuterium labeled Vitamin B5 calcium[1].

HY-W017086S

Dibenzo[b,d]furan-d₈		99.90%
Dibenzo[b,d]furan-d₈ is the deuterium labeled Dibenzo[b,d]furan[1].

HY-41700S

D-Alanine-d₃		99.31%
D-Alanine-d₃ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-16561S

Resveratrol-d₄		99.36%
Resveratrol-d₄ is the deuterium labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator. Resveratrol is a potent pregnane X receptor (PXR) inhibitor. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model. Resveratrol increases production of NO in endothelial cells.

HY-N0667S2

L-Asparagine-¹⁵N₂ monohydrate		≥98.0%
L-Asparagine-¹⁵N₂ monohydrate is the ¹⁵N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

HY-W010098S1

Terephthalic acid-¹³C₂		99.60%
Terephthalic acid-¹³C₂ is the ¹³C-labeled Terephthalic acid. Terephthalic acid is one isomer of the three phthalic, a precursor to the polyester PET, used to make clothing and plastic bottles.

HY-40354AS

Tofacitinib-d₃ citrate		99.14%
Tofacitinib-d₃ (citrate) is deuterium labeled Tofacitinib (citrate). Tofacitinib citrate is an orally available JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively. Tofacitinib citrate has antibacterial, antifungal and antiviral activities.

HY-N0623S3

L-Tryptophan-1-¹³C		99.00%
L-Tryptophan-1-¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-W013049S4

Docosanoic acid-d₄-1		≥99.0%
Docosanoic acid-d₄-1 (Behenic acid-d₄-1) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a K_d of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.

HY-W004290S

Methyl heptadecanoate-d₃₃		99.04%
Methyl heptadecanoate-d₃₃ is the deuterium labeled Methyl heptadecanoate. Methyl heptadecanoate is a fatty acid methyl ester[1].

HY-113128S

sn-Glycerol 3-phosphate-¹³C disodium		98.7%
sn-Glycerol 3-phosphate-¹³C₃ disodium is the ¹³C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.

HY-W251598S

Bicarbonate-¹³C sodium		≥98.0%
Bicarbonate-¹³C (sodium) is the ¹³C labeled Bicarbonate sodium[1].

HY-17503AS

Metoprolol-d₇ hydrochloride		99.71%
Metoprolol-d₇ (hydrochloride) is the deuterium labeled Metoprolol. Metoprolol is an orally active, selective β1-adrenoceptor antagonist. Metoprolol shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3][4].

HY-160144S

Lomedeucitinib		99.75%
Lomedeucitinib (BMS-986322) is a tyrosine protein kinase (TYK2) inhibitor.

HY-B0228S10

(R)-3-Hydroxybutanoic acid-¹³C₂ sodium		≥98.0%
(R)-3-Hydroxybutanoic acid-¹³C₂ (sodium) is the ¹³C labeled (R)-3-Hydroxybutanoic acid (sodium) (HY-W015851). (R)-3-Hydroxybutanoic acid (sodium) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2][3].

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