2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Autophagy
  3. RAR/RXR Autophagy
  4. (-)-Talarozole

(-)-Talarozole is a potent inhibitor of retinoic acid metabolism extracted from patent WO 1997049704 A1.

For research use only. We do not sell to patients.

(-)-Talarozole Chemical Structure

(-)-Talarozole Chemical Structure

CAS No. : 201410-67-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 389 In-stock
Solution
10 mM * 1 mL in DMSO USD 389 In-stock
Solid
1 mg USD 228 In-stock
5 mg USD 468 In-stock
10 mg USD 780 In-stock
25 mg USD 1800 In-stock
50 mg USD 2880 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of (-)-Talarozole:

(-)-Talarozole Related Antibodies

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Description

(-)-Talarozole is a potent inhibitor of retinoic acid metabolism extracted from patent WO 1997049704 A1.

IC50 & Target

retinoic acid[1]
Molecular Weight

377.51

Formula

C21H23N5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCC(CC)C(C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4N=CN=C4.[(-)].[Rotation]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 72.5 mg/mL (192.05 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6489 mL 13.2447 mL 26.4894 mL
5 mM 0.5298 mL 2.6489 mL 5.2979 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6489 mL 13.2447 mL 26.4894 mL 66.2234 mL
5 mM 0.5298 mL 2.6489 mL 5.2979 mL 13.2447 mL
10 mM 0.2649 mL 1.3245 mL 2.6489 mL 6.6223 mL
15 mM 0.1766 mL 0.8830 mL 1.7660 mL 4.4149 mL
20 mM 0.1324 mL 0.6622 mL 1.3245 mL 3.3112 mL
25 mM 0.1060 mL 0.5298 mL 1.0596 mL 2.6489 mL
30 mM 0.0883 mL 0.4415 mL 0.8830 mL 2.2074 mL
40 mM 0.0662 mL 0.3311 mL 0.6622 mL 1.6556 mL
50 mM 0.0530 mL 0.2649 mL 0.5298 mL 1.3245 mL
60 mM 0.0441 mL 0.2207 mL 0.4415 mL 1.1037 mL
80 mM 0.0331 mL 0.1656 mL 0.3311 mL 0.8278 mL
100 mM 0.0265 mL 0.1324 mL 0.2649 mL 0.6622 mL
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(-)-Talarozole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-Talarozole201410-67-5RAR/RXRAutophagyRetinoic acid receptorsRetinoid X receptorsInhibitorinhibitorinhibit

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