CYD19 (Synonyms: Snail/HDAC-IN-1)

Name: CYD19
Brand: MedChemExpress
SKU: HY-144315
Rating: 4.5 (1 reviews)

Cat. No.: HY-144315 Purity: 99.76%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

CYD19 is a potent Snail/HDAC dual target inhibitor. CYD19 displays potent inhibitory activity against HDAC1 with an IC₅₀ of 0.405 μM and potent inhibition against Snail with a K_d of 0.18 μM. CYD19 increases histone H4 acetylation in HCT-116 cells and decreases the expression of Snail protein to induce cell apoptosis.

For research use only. We do not sell to patients.

CAS No. : 2415281-52-4

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

MCE Biological Validation

: HCT 116 cells were seeded at 1*10⁵ cells/well in a 24-well plate and were cultured overnight. Then, cells are treated with 0-75 nM CYD19 (HY-144315) for 48 hours to assess the expression of Snail-1 via Western blotting. The results demonstrated that CYD19 inhibited the expression of Snail-1 at 75 and 100 nM. Primary antibody: SNAI1 antibody (HY-P81135), β-actin antibody (HY-P80438).

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

HDAC1

0.405 μM (IC₅₀)

Snail

0.18 μM (Kd)

Cellular Effect

Cell Line	Type	Value	Description	References
786-0	GI₅₀	0.466 μM Compound: 9n	Antiproliferative activity against human 786-0 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human 786-0 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
A498	GI₅₀	0.623 μM Compound: 9n	Antiproliferative activity against human A498 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human A498 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
A549	GI₅₀	0.886 μM Compound: 9n	Antiproliferative activity against human A549 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human A549 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
ACHN	GI₅₀	1.24 μM Compound: 9n	Antiproliferative activity against human ACHN cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human ACHN cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
BT-549	GI₅₀	0.296 μM Compound: 9n	Antiproliferative activity against human BT-549 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human BT-549 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
CCRF-CEM	GI₅₀	0.411 μM Compound: 9n	Antiproliferative activity against human CCRF-CEM cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human CCRF-CEM cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
COLO 205	GI₅₀	0.296 μM Compound: 9n	Antiproliferative activity against human COLO 205 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human COLO 205 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
DU-145	GI₅₀	0.461 μM Compound: 9n	Antiproliferative activity against human DU-145 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human DU-145 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
EKVX	GI₅₀	0.919 μM Compound: 9n	Antiproliferative activity against human EKVX cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human EKVX cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
HCC 2998	GI₅₀	0.677 μM Compound: 9n	Antiproliferative activity against human HCC 2998 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human HCC 2998 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
HCT-116	IC₅₀	0.0751 μM Compound: 9n	Antiproliferative activity against human HCT-116 cells assessed as cell viability at 1 uM incubated for 72 hrs by luminescence assay Antiproliferative activity against human HCT-116 cells assessed as cell viability at 1 uM incubated for 72 hrs by luminescence assay	[PMID: 34995925]
HCT-116	GI₅₀	0.494 μM Compound: 9n	Antiproliferative activity against human HCT-116 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human HCT-116 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
HCT-15	GI₅₀	0.424 μM Compound: 9n	Antiproliferative activity against human HCT-15 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human HCT-15 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
HL-60	GI₅₀	0.268 μM Compound: 9n	Antiproliferative activity against human HL-60 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human HL-60 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
HOP-62	GI₅₀	0.556 μM Compound: 9n	Antiproliferative activity against human HOP-62 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human HOP-62 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
HOP-92	GI₅₀	3.68 μM Compound: 9n	Antiproliferative activity against human HOP-92 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human HOP-92 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
Hs-578T	GI₅₀	0.429 μM Compound: 9n	Antiproliferative activity against human Hs-578T cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human Hs-578T cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
HT-29	GI₅₀	0.322 μM Compound: 9n	Antiproliferative activity against human HT-29 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human HT-29 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
IGROV-1	GI₅₀	0.558 μM Compound: 9n	Antiproliferative activity against human IGROV-1 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human IGROV-1 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
K562	GI₅₀	0.0487 μM Compound: 9n	Antiproliferative activity against human K562 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human K562 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
KM12	GI₅₀	0.284 μM Compound: 9n	Antiproliferative activity against human KM12 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human KM12 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
LOX IMVI	GI₅₀	0.665 μM Compound: 9n	Antiproliferative activity against human LOX IMVI cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human LOX IMVI cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
M14	GI₅₀	0.289 μM Compound: 9n	Antiproliferative activity against human M14 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human M14 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
Malme-3M	GI₅₀	1.83 μM Compound: 9n	Antiproliferative activity against human Malme-3M cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human Malme-3M cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
MCF7	GI₅₀	0.0518 μM Compound: 9n	Antiproliferative activity against human MCF7 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human MCF7 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
MDA-MB-231	GI₅₀	0.854 μM Compound: 9n	Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
MDA-MB-435	GI₅₀	0.0361 μM Compound: 9n	Antiproliferative activity against human MDA-MB-435 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human MDA-MB-435 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
MDA-MB-468	GI₅₀	0.432 μM Compound: 9n	Antiproliferative activity against human MDA-MB-468 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human MDA-MB-468 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
MOLT-4	GI₅₀	0.508 μM Compound: 9n	Antiproliferative activity against human MOLT-4 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human MOLT-4 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
NCI/ADR-RES	GI₅₀	1.98 μM Compound: 9n	Antiproliferative activity against human NCI/ADR-RES cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human NCI/ADR-RES cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
NCI-H226	GI₅₀	2.7 μM Compound: 9n	Antiproliferative activity against human NCI-H226 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human NCI-H226 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
NCI-H23	GI₅₀	0.603 μM Compound: 9n	Antiproliferative activity against human NCI-H23 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human NCI-H23 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
NCI-H322M	GI₅₀	1.01 μM Compound: 9n	Antiproliferative activity against human NCI-H322M cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human NCI-H322M cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
NCI-H460	GI₅₀	0.395 μM Compound: 9n	Antiproliferative activity against human NCI-H460 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human NCI-H460 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
NCI-H522	GI₅₀	0.0488 μM Compound: 9n	Antiproliferative activity against human NCI-H522 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human NCI-H522 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
OVCAR-3	GI₅₀	0.202 μM Compound: 9n	Antiproliferative activity against human OVCAR-3 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human OVCAR-3 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
OVCAR-4	GI₅₀	1.66 μM Compound: 9n	Antiproliferative activity against human OVCAR-4 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human OVCAR-4 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
OVCAR-5	GI₅₀	0.657 μM Compound: 9n	Antiproliferative activity against human OVCAR-5 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human OVCAR-5 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
OVCAR-8	GI₅₀	0.483 μM Compound: 9n	Antiproliferative activity against human OVCAR-8 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human OVCAR-8 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
PC-3	GI₅₀	0.355 μM Compound: 9n	Antiproliferative activity against human PC-3 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human PC-3 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
RPMI-8226	GI₅₀	0.514 μM Compound: 9n	Antiproliferative activity against human RPMI-8226 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human RPMI-8226 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
RXF 393	GI₅₀	0.301 μM Compound: 9n	Antiproliferative activity against human RXF 393 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human RXF 393 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SF-268	GI₅₀	1.12 μM Compound: 9n	Antiproliferative activity against human SF-268 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SF-268 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SF-295	GI₅₀	0.354 μM Compound: 9n	Antiproliferative activity against human SF-295 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SF-295 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SF-539	GI₅₀	0.282 μM Compound: 9n	Antiproliferative activity against human SF-539 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SF-539 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SK-MEL-2	GI₅₀	0.617 μM Compound: 9n	Antiproliferative activity against human SK-MEL-2 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SK-MEL-2 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SK-MEL-28	GI₅₀	2.83 μM Compound: 9n	Antiproliferative activity against human SK-MEL-28 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SK-MEL-28 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SK-MEL-5	GI₅₀	0.334 μM Compound: 9n	Antiproliferative activity against human SK-MEL-5 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SK-MEL-5 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SK-OV-3	GI₅₀	0.339 μM Compound: 9n	Antiproliferative activity against human SK-OV-3 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SK-OV-3 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SN12C	GI₅₀	1.25 μM Compound: 9n	Antiproliferative activity against human SN12C cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SN12C cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SNB-19	GI₅₀	0.536 μM Compound: 9n	Antiproliferative activity against human SNB-19 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SNB-19 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SNB-75	GI₅₀	0.198 μM Compound: 9n	Antiproliferative activity against human SNB-75 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SNB-75 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SR	GI₅₀	0.068 μM Compound: 9n	Antiproliferative activity against human SR cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SR cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
SW-620	GI₅₀	0.426 μM Compound: 9n	Antiproliferative activity against human SW-620 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human SW-620 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
T47D	GI₅₀	1.12 μM Compound: 9n	Antiproliferative activity against human T47D cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human T47D cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
TK-10	GI₅₀	1.21 μM Compound: 9n	Antiproliferative activity against human TK-10 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human TK-10 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
U-251	GI₅₀	0.343 μM Compound: 9n	Antiproliferative activity against human U-251 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human U-251 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
UACC-257	GI₅₀	3.69 μM Compound: 9n	Antiproliferative activity against human UACC-257 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human UACC-257 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
UACC-62	GI₅₀	0.347 μM Compound: 9n	Antiproliferative activity against human UACC-62 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human UACC-62 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]
UO-31	GI₅₀	1.33 μM Compound: 9n	Antiproliferative activity against human UO-31 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay Antiproliferative activity against human UO-31 cells assessed as growth inhibition incubated for 72 hrs by luminescence assay	[PMID: 34995925]

In Vitro

CYD19 (compound 9n) shows antiproliferative activity in HCT-116 cell lines with an IC₅₀ of 0.0751 μM. CYD19 shows a good inhibitory effect on NCI–H522 (GI₅₀=0.0488 μM), MDA-MB-435 (GI₅₀=0.0361 μM), and MCF7 (GI₅₀=0.0518 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

488.54

Formula

C₂₄H₂₁FN₈OS

CAS No.

2415281-52-4

Appearance

Solid

Color

White to light yellow

SMILES

O=C(NC1=CC=C(F)C=C1N)C2=CC=C(CSC(N=C3NC4=NNC(C)=C4)=NN5C3=CC=C5)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (255.86 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0469 mL	10.2346 mL	20.4692 mL
5 mM	0.4094 mL	2.0469 mL	4.0938 mL
10 mM	0.2047 mL	1.0235 mL	2.0469 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Purity & Documentation

Purity: 99.76%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (251 KB) HNMR (417 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Cui H, et al. Design and synthesis of dual inhibitors targeting snail and histone deacetylase for the treatment of solid tumour cancer. Eur J Med Chem. 2022;229:114082. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0469 mL	10.2346 mL	20.4692 mL	51.1729 mL
	5 mM	0.4094 mL	2.0469 mL	4.0938 mL	10.2346 mL
	10 mM	0.2047 mL	1.0235 mL	2.0469 mL	5.1173 mL
	15 mM	0.1365 mL	0.6823 mL	1.3646 mL	3.4115 mL
	20 mM	0.1023 mL	0.5117 mL	1.0235 mL	2.5586 mL
	25 mM	0.0819 mL	0.4094 mL	0.8188 mL	2.0469 mL
	30 mM	0.0682 mL	0.3412 mL	0.6823 mL	1.7058 mL
	40 mM	0.0512 mL	0.2559 mL	0.5117 mL	1.2793 mL
	50 mM	0.0409 mL	0.2047 mL	0.4094 mL	1.0235 mL
	60 mM	0.0341 mL	0.1706 mL	0.3412 mL	0.8529 mL
	80 mM	0.0256 mL	0.1279 mL	0.2559 mL	0.6397 mL
	100 mM	0.0205 mL	0.1023 mL	0.2047 mL	0.5117 mL

CYD19 Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CYD192415281-52-4Snail/HDAC-IN-1CYD 19CYD-19HDACHistone deacetylasesantiproliferative activityHCT-116 cellsNCI–H522MCF7histone H4 acetylationtumorSnailHDAC1Inhibitorinhibitorinhibit

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CYD19 (Synonyms: Snail/HDAC-IN-1)

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