2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. DDMS

DDMS  (Synonyms: Dibromo-dodecenyl-methylsulfimide)

Cat. No.: HY-121188 Purity: 99.19%
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DDMS (Dibromo-dodecenyl-methylsulfimide) is a selective 20-HETE production inhibitor. DDMS attenuates the vasodilatory response to sodium nitroprusside (SNP).

For research use only. We do not sell to patients.

DDMS Chemical Structure

DDMS Chemical Structure

CAS No. : 206052-03-1

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1 mg USD 85 In-stock
5 mg USD 320 In-stock
10 mg USD 540 In-stock
25 mg USD 1100 In-stock
50 mg USD 1760 In-stock
100 mg USD 2820 In-stock
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DDMS Related Antibodies

Top Publications Citing Use of Products

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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Description

DDMS (Dibromo-dodecenyl-methylsulfimide) is a selective 20-HETE production inhibitor. DDMS attenuates the vasodilatory response to sodium nitroprusside (SNP)[1].

IC50 & Target

20-HETE[1]
Molecular Weight

433.20

Formula

C13H23Br2NO3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

Br/C(Br)=C\CCCCCCCCCC(NS(=O)(C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (230.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3084 mL 11.5420 mL 23.0840 mL
5 mM 0.4617 mL 2.3084 mL 4.6168 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3084 mL 11.5420 mL 23.0840 mL 57.7101 mL
5 mM 0.4617 mL 2.3084 mL 4.6168 mL 11.5420 mL
10 mM 0.2308 mL 1.1542 mL 2.3084 mL 5.7710 mL
15 mM 0.1539 mL 0.7695 mL 1.5389 mL 3.8473 mL
20 mM 0.1154 mL 0.5771 mL 1.1542 mL 2.8855 mL
25 mM 0.0923 mL 0.4617 mL 0.9234 mL 2.3084 mL
30 mM 0.0769 mL 0.3847 mL 0.7695 mL 1.9237 mL
40 mM 0.0577 mL 0.2886 mL 0.5771 mL 1.4428 mL
50 mM 0.0462 mL 0.2308 mL 0.4617 mL 1.1542 mL
60 mM 0.0385 mL 0.1924 mL 0.3847 mL 0.9618 mL
80 mM 0.0289 mL 0.1443 mL 0.2886 mL 0.7214 mL
100 mM 0.0231 mL 0.1154 mL 0.2308 mL 0.5771 mL
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DDMS Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DDMS206052-03-1Dibromo-dodecenyl-methylsulfimideCytochrome P450CYPssodium nitroprussidevasodilatory response20-HETEInhibitorinhibitorinhibit

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