2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. (E/Z)-HA155

(E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis.

For research use only. We do not sell to patients.

(E/Z)-HA155 Chemical Structure

(E/Z)-HA155 Chemical Structure

CAS No. : 1229652-22-5

Size Price Stock Quantity
1 mg USD 40 In-stock
5 mg USD 120 In-stock
10 mg USD 190 In-stock
25 mg USD 395 In-stock
50 mg USD 590 In-stock
100 mg USD 830 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (E/Z)-HA155:

(E/Z)-HA155 Related Antibodies

Top Publications Citing Use of Products

View All Phosphodiesterase (PDE) Isoform Specific Products:

View All Isoforms
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • Biological Activity

  • Purity & Documentation

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  • Customer Review

Description

(E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis[1].

IC50 & Target

Autotaxin[1]
Molecular Weight

463.29

Formula

C24H19BFNO5S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

OB(O)C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C(C3=O)\SC(N3CC4=CC=C(C=C4)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (269.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1585 mL 10.7924 mL 21.5848 mL
5 mM 0.4317 mL 2.1585 mL 4.3170 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1585 mL 10.7924 mL 21.5848 mL 53.9619 mL
5 mM 0.4317 mL 2.1585 mL 4.3170 mL 10.7924 mL
10 mM 0.2158 mL 1.0792 mL 2.1585 mL 5.3962 mL
15 mM 0.1439 mL 0.7195 mL 1.4390 mL 3.5975 mL
20 mM 0.1079 mL 0.5396 mL 1.0792 mL 2.6981 mL
25 mM 0.0863 mL 0.4317 mL 0.8634 mL 2.1585 mL
30 mM 0.0719 mL 0.3597 mL 0.7195 mL 1.7987 mL
40 mM 0.0540 mL 0.2698 mL 0.5396 mL 1.3490 mL
50 mM 0.0432 mL 0.2158 mL 0.4317 mL 1.0792 mL
60 mM 0.0360 mL 0.1799 mL 0.3597 mL 0.8994 mL
80 mM 0.0270 mL 0.1349 mL 0.2698 mL 0.6745 mL
100 mM 0.0216 mL 0.1079 mL 0.2158 mL 0.5396 mL
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(E/Z)-HA155 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E/Z)-HA1551229652-22-5Phosphodiesterase (PDE)AutotaxinCancerFibrotic diseasesInflammationPainAngiogenesisInhibitorinhibitorinhibit

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