2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR-IN-37

EGFR-IN-37 is a potent inhibitor of EGFR. EGFR-IN-37 is an anti-tumor agent with low toxic side effects. EGFR-IN-39 is an acrylamide derivative compound. Overexpression and mutation of the epidermal growth factor receptor (EGFR) has been clearly demonstrated to lead to uncontrollable cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-37 has the potential for the research of diseases associated with EGFR mutations (extracted from patent WO2021185348A1, compound 7).

For research use only. We do not sell to patients.

EGFR-IN-37 Chemical Structure

EGFR-IN-37 Chemical Structure

CAS No. : 2711105-53-0

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EGFR-IN-37 Related Antibodies

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Description

EGFR-IN-37 is a potent inhibitor of EGFR. EGFR-IN-37 is an anti-tumor agent with low toxic side effects. EGFR-IN-39 is an acrylamide derivative compound. Overexpression and mutation of the epidermal growth factor receptor (EGFR) has been clearly demonstrated to lead to uncontrollable cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-37 has the potential for the research of diseases associated with EGFR mutations (extracted from patent WO2021185348A1, compound 7)[1].

Molecular Weight

488.97

Formula

C26H25ClN6O2
CAS No.
SMILES

NC1=NC=CN2C([C@@]3([H])CN(CCC3)C(C=C)=O)=NC(C4=CC(Cl)=C(C=C4)OCC5=CC=CC=N5)=C12
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EGFR-IN-37 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR-IN-372711105-53-0EGFREpidermal growth factor receptorErbB-1HER1anti-tumorlow toxic side effectacrylamide derivativecell growthNSCLCEGFR mutationInhibitorinhibitorinhibit

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