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  4. Fibrostatin C

Fibrostatin C (P-23924C) is an orally active prolyl hydroxylase inhibitor that also inhibits collagen biosynthesis. Fibrostatin C also increases the number of cytoplasmic granules immunoreactive with antibodies to collagen I or III. Fibrostatin C inhibits the secretion of type I collagen in Tenon's capsule fibroblasts. Fibrostatin C is promising for research of the wound fibrotic response in the wound of glaucoma filtering surgery.

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Fibrostatin C Chemical Structure

Fibrostatin C Chemical Structure

CAS No. : 91776-47-5

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Fibrostatin C Related Antibodies

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Description

Fibrostatin C (P-23924C) is an orally active prolyl hydroxylase inhibitor that also inhibits collagen biosynthesis. Fibrostatin C also increases the number of cytoplasmic granules immunoreactive with antibodies to collagen I or III. Fibrostatin C inhibits the secretion of type I collagen in Tenon's capsule fibroblasts. Fibrostatin C is promising for research of the wound fibrotic response in the wound of glaucoma filtering surgery[1][2].

Molecular Weight

409.41

Formula

C18H19NO8S
CAS No.
SMILES

O=C([C@@H](NC(C)=O)CSCC(C(O)=C1C2=O)=C(C=C1C(C(OC)=C2)=O)OC)O
Structure Classification
Initial Source

Streptomyces
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
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Fibrostatin C Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fibrostatin C91776-47-5P-23924COthersprolyl hydroxylasecollagencytoplasmic granulesTenon's capsule fibroblastswound fibrotic responseInhibitorinhibitorinhibit

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