1. Gene
  2. HNRNPUL1 - heterogeneous nuclear ribonucleoprotein U like 1 Gene

HNRNPUL1 - heterogeneous nuclear ribonucleoprotein U like 1 Gene

Homo sapiens

Also known as E1BAP5; E1B-AP5; HNRPUL1

Gene ID: 11100 | Gene type: protein coding

About HNRNPUL1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,262,557-41,307,787 (from NCBI)

This gene has 21 transcripts (splice variants), 205 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 41.5), ovary (RPKM 40.7) and 25 other tissues.

Summary

This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells. [provided by RefSeq, Mar 2016]

HNRNPUL1 Products(5)

mRNA Protein Name
NM_001301016.3 NP_001287945.1 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform e
NM_001321208.2 NP_001308137.1 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d
NM_001321211.2 NP_001308140.1 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d
NM_007040.6 NP_008971.2 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform a
NM_144732.5 NP_653333.1 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
11513728 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12489984 GOA
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
11513728 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HNRNPUL1 Protein Structure

SAP

SAP: SAP domain (5 - 37)

SPRY

SPRY: SPRY domain (255 - 386)

AAA_33

AAA_33: AAA domain (424 - 568)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 856 a.a.
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein U-like protein 1

E1B 55kDa associated protein 5

HNRNPUL1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra HNRNPUL1 Q9BUJ2 PPP1R13B Homo sapiens Q96KQ4
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 PPP1R13B Homo sapiens Q96KQ4
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 VPS37C Homo sapiens A5D8V6
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 VPS37C Homo sapiens A5D8V6
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 SF3B4 Homo sapiens Q15427
Y2H
22365833
Intra HNRNPUL1 Q9BUJ2 SF3B4 Homo sapiens Q15427
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 SF3B4 Homo sapiens Q15427
Y2H Array
25416956
Intra HNRNPUL1 Q9BUJ2 PIAS2 Homo sapiens O75928-2
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 PIAS2 Homo sapiens O75928-2
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 HNRNPF Homo sapiens P52597
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 HNRNPF Homo sapiens P52597
Y2H Array
29892012
Intra HNRNPUL1 Q9BUJ2 HNRNPF Homo sapiens P52597
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 HNRNPF Homo sapiens P52597
Y2H
22365833
Intra HNRNPUL1 Q9BUJ2 BRD7 Homo sapiens Q9NPI1
Anti Bait CoIP
12489984
Intra HNRNPUL1 Q9BUJ2 BRD7 Homo sapiens Q9NPI1
Y2H
12489984
Intra HNRNPUL1 Q9BUJ2 BRD7 Homo sapiens Q9NPI1
Pull Down
12489984
Intra HNRNPUL1 Q9BUJ2 BRD7 Homo sapiens Q9NPI1
Fluorescence
12489984
Intra HNRNPUL1 Q9BUJ2 RBM4B Homo sapiens Q9BQ04
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 SORBS3 Homo sapiens O60504
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 MAPK1IP1L Homo sapiens Q8NDC0
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 MAPK1IP1L Homo sapiens Q8NDC0
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Array
31515488
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Array
25416956
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H
21516116
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Array
29892012
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 KLHDC7B Homo sapiens Q96G42
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 KLHDC7B Homo sapiens Q96G42
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Array
25416956
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Array
29892012
Cross: Cross-species interaction Intra: Intraspecies interaction

Orthologs Information

Species Symbol Source ID
Macaca mulatta HNRNPUL1 VGNC VGNC:73401
Bos taurus HNRNPUL1 VGNC VGNC:50035
Rattus norvegicus HNRNPUL1 RGD RGD:1307456
Mus musculus HNRNPUL1 MGD MGI:2443517
Felis catus HNRNPUL1 VGNC VGNC:62828
Canis familiaris HNRNPUL1 VGNC VGNC:53724