2. Gene
  3. FSTL1 - follistatin like 1 Gene

FSTL1 - follistatin like 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FRP; FSL1; OCC1; OCC-1; tsc36; MIR198

Gene ID: 11167 | Gene type: protein coding

About FSTL1

Cytogenetic location: 3q13.33 Genomic coordinates (GRCh38): 3:120,392,293-120,450,992 (from NCBI)

This gene has 10 transcripts (splice variants), 233 orthologues and 6 paralogues. Broad expression in placenta (RPKM 238.4), gall bladder (RPKM 177.0) and 21 other tissues.

Summary

This gene encodes a protein with similarity to Follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]

FSTL1 Products(1)

mRNA Protein Name
NM_007085.5 NP_009016.1 follistatin-related protein 1 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19060904 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FSTL1 Protein Structure

FOLN

FOLN: Follistatin/Osteonectin-like EGF domain (31 - 52)

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (58 - 98)

  • 0
  • 100
  • 200
  • 308 a.a.
Protein Preferred Names Protein Names

follistatin-related protein 1

follistatin-like protein 1

Recombinant FSTL1 Proteins

Cat. No. Product Name Accession Purity
HY-P70412 Follistatin-like 1/FSTL1 Protein, Human (HEK293, His) Q12841 (E21-I308) ≥95%
HY-P72640 Follistatin-like 1/FSTL1 Protein, Human (His) Q12841 (E21-I308) ≥95%

Related Diseases

Diseases Alias
Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis
Arthritis

Inflammatory Joint Disease

Inflammatory Disorder Of Joint
Coronary Aneurysm

Aneurysm Of Coronary Vessels

Aneurysmal Lesion Of Coronary Artery

Arteriovenous Aneurysm Of Coronary Vessels
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05128 FSTL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FSTL1 RGD RGD:68955
Bos taurus FSTL1 VGNC VGNC:29135
Macaca mulatta FSTL1 VGNC VGNC:72824
Canis familiaris FSTL1 VGNC VGNC:49898
Mus musculus FSTL1 MGD MGI:102793
Felis catus FSTL1 VGNC VGNC:62380
Others FSTL1 NCBI