2. Gene
  3. F3 - coagulation factor III Gene

F3 - coagulation factor III Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TF; Cf3; Cf-3; CD142

Gene ID: 14066 | Gene type: protein coding

About F3

Summary

This gene encodes a membrane-bound glycoprotein that forms the primary physiological initiator of the blood coagulation process following vascular damage. The encoded protein binds to coagulation factor VIIa and the ensuing complex catalyzes the proteolytic activation of coagulation factors IX and X. Mice lacking encoded protein die in utero resulting from massive hemorrhaging in both extraembryonic and embryonic vessels. A severe deficiency of the encoded protein in mice results in impaired uterine homeostasis, shorter life spans due to spontaneous fatal hemorrhages and cardiac fibrosis. [provided by RefSeq, Aug 2015]

F3 Products(1)

mRNA Protein Name
NM_010171.3 NP_034301.3 tissue factor precursor
Protein Preferred Names Protein Names

tissue factor

Recombinant F3 Proteins

Cat. No. Product Name Accession Purity
HY-P71127 Tissue Factor Protein, Mouse (HEK293, His) P20352 (A29-E251) ≥95%

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104010 Asciminib Inhibitor 99.88% Yes
HY-104010A Asciminib hydrochloride Inhibitor 99.93% Yes
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-B2203 Monocalcium glycerophosphate Inhibitor ≥98.0% Phase 2
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99271 Tisotumab 95.00% Phase 3
Pre-clinical Phase
Bioactive Molecules (82)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18960 CHZ868 Inhibitor 99.56% Unkown
HY-130709 PROTAC CDK2/9 Degrader-1 Inhibitor 99.85% Unkown
HY-125845 (S,R,S)-AHPC 99.13% Unkown
HY-13491 GNF-5837 Inhibitor 99.65% Unkown
HY-11007 GNF-2 Inhibitor 98.73% Unkown
HY-125834 GMB-475 98.98% Unkown
HY-N0600 Ginsenoside F3 Modulator 99.84% Unkown
HY-133551 WF-47-JS03 Inhibitor 99.63% Unkown
HY-12291 HG6-64-1 Inhibitor 96.45% Unkown
HY-131906 JAK2-IN-7 99.15% Unkown
HY-18952A (Z)-SU5614 98.43% Unkown
HY-113437A 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium ≥98.0% Unkown
HY-156467 Neladalkib Inhibitor 99.90% Unkown
HY-156467A Neladalkib TFA Inhibitor / Unkown
HY-RS03482 CYP4F3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-113437AS 1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium ≥99.0% Unkown
HY-110026 GTP-14564 Inhibitor 99.91% Unkown
HY-113437 1,2-Dipalmitoyl-sn-glycerol 3-phosphate / Unkown
HY-110402 (S,R,S)-AHPC TFA / Unkown
HY-159147 SIA​​IS039 / Unkown
HY-136526 BCR-ABL-IN-3 Inhibitor / Unkown
HY-101763B (S,R,S)-AHPC dihydrochloride / Unkown
HY-107662 TCS PrP Inhibitor 13 Inducer 98.82% Unkown
HY-112378 D-65476 Inhibitor / Unkown
HY-116597 L-783483 Agonist / Unkown
HY-12083 PPY-A Inhibitor / Unkown
HY-131244 ALK-IN-9 Inhibitor / Unkown
HY-142922 BCR-ABL-IN-4 Inhibitor / Unkown
HY-144451 TRK-IN-12 Inhibitor / Unkown
HY-146807 Type II TRK inhibitor 1 Inhibitor / Unkown
HY-147813 HIF-1α-IN-3 Inhibitor / Unkown
HY-149965 TRK-IN-23 / Unkown
HY-154465 3’-F-3’-dG(iBu)-2’-phosphoramidite / Unkown
HY-155302 FLT3-IN-22 Inhibitor / Unkown
HY-156086 TRK-IN-24 Inhibitor / Unkown
HY-156102 c-ABL-IN-5 / Unkown
HY-157432 EGFR-IN-97 / Unkown
HY-161269 EGFR-IN-101 Inhibitor / Unkown
HY-162645 BPR5K230 Inhibitor / Unkown
HY-162881 DS06652923 Inhibitor / Unkown
HY-163004 Type II TRK inhibitor 2 Inhibitor / Unkown
HY-163366 TRK-IN-28 Inhibitor / Unkown
HY-164397 XMU-MP-5 / Unkown
HY-16983 GNE-3500 Antagonist / Unkown
HY-E70134 Endo-β-N-acetylglucosaminidase F3 / Unkown
HY-N8448 3,4-Di-O-caffeoyl quinic acid methyl ester Inhibitor / Unkown
HY-R01574 hsa-miR-518f-3p mimic / Unkown
HY-R01574A hsa-miR-518f-3p agomir / Unkown
HY-R01603 hsa-miR-520f-3p mimic / Unkown
HY-R01603A hsa-miR-520f-3p agomir / Unkown
HY-R01683 hsa-miR-548f-3p mimic / Unkown
HY-R01683A hsa-miR-548f-3p agomir / Unkown
HY-R03051 mmu-miR-344f-3p mimic / Unkown
HY-R03051A mmu-miR-344f-3p agomir / Unkown
HY-R03176 mmu-miR-466f-3p mimic / Unkown
HY-R03176A mmu-miR-466f-3p agomir / Unkown
HY-R03467 mmu-miR-669f-3p mimic / Unkown
HY-R03467A mmu-miR-669f-3p agomir / Unkown
HY-RI01574 hsa-miR-518f-3p inhibitor / Unkown
HY-RI01574A hsa-miR-518f-3p antagomir / Unkown
HY-RI01603 hsa-miR-520f-3p inhibitor / Unkown
HY-RI01603A hsa-miR-520f-3p antagomir / Unkown
HY-RI01683 hsa-miR-548f-3p inhibitor / Unkown
HY-RI01683A hsa-miR-548f-3p antagomir / Unkown
HY-RI03051 mmu-miR-344f-3p inhibitor / Unkown
HY-RI03051A mmu-miR-344f-3p antagomir / Unkown
HY-RI03176 mmu-miR-466f-3p inhibitor / Unkown
HY-RI03176A mmu-miR-466f-3p antagomir / Unkown
HY-RI03467 mmu-miR-669f-3p inhibitor / Unkown
HY-RI03467A mmu-miR-669f-3p antagomir / Unkown
HY-RS04112 E2F3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04643 F3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10899 POU2F3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10902 POU3F3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10906 POU4F3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13207 SLC35F3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-113777 22-HDHA / Unkown
HY-116008 8-iso Prostaglandin F3α / Unkown
HY-121888 20-HEPE / Unkown
HY-129764 Prostaglandin F3α / Unkown
HY-129764A (17E)-Prostaglandin F3α / Unkown
HY-154031 3'-F-3'-dA(Bz)-2'-Phosphoramidite / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F3 NCBI NCBI:2152
Canis familiaris F3 NCBI NCBI:490153
Macaca fascicularis F3 NCBI NCBI:102131431
Leporidae F3 NCBI
Rattus norvegicus F3 NCBI NCBI:25584
Macaca mulatta F3 NCBI NCBI:714456