2. Gene
  3. Il13 - interleukin 13 Gene

Il13 - interleukin 13 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Il-13

Gene ID: 16163 | Gene type: protein coding

About Il13

Chromosome 11: 53,522,151-53,525,529 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 88 orthologues and is associated with 55 phenotypes. Biased expression in thymus adult (RPKM 2.8), testis adult (RPKM .6) and 2 other tissues.

Summary

Predicted to enable interleukin-13 receptor binding activity. Involved in positive regulation of cold-induced thermogenesis and positive regulation of macrophage activation. Acts upstream of or within cellular response to cytokine stimulus; inflammatory response; and positive regulation of immune effector process. Located in cytoplasm; external side of plasma membrane; and extracellular space. Is expressed in gut; liver; male reproductive gland or organ; and thymus. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13). [provided by Alliance of Genome Resources, Apr 2022]

Il13 Products(1)

mRNA Protein Name
NM_008355.3 NP_032381.1 interleukin-13 precursor

Il13 Protein Structure

IL13

IL13: pfam03487 (20 - 129)

  • 0
  • 100
  • 131 a.a.
Protein Preferred Names Protein Names

interleukin-13

T-cell activation protein P600

Recombinant Il13 Proteins

Cat. No. Product Name Accession Purity
HY-P7076A IL-13 Protein, Mouse (CHO, His) P20109 (P22-F131) ≥95%
HY-P70460 IL-13 Protein, Mouse P20109 (S26-F131) ≥95%
HY-P72595 IL-13 Protein, Mouse (HEK293, His) P20109 (P22-F131) ≥95%
HY-P73168 IL-13 Protein, Mouse (HEK293) P20109 (A19-F131) ≥95%
HY-P700192AF Animal-Free IL-13 Protein, Mouse (His) P20109 (P22-F131) ≥95%

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0539 Desloratadine 99.83% Yes
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9926 Dupilumab Inhibitor ≥99.2% Unkown
HY-P99025 Lebrikizumab Inhibitor 99.90% Unkown
HY-P99053 Tralokinumab Inhibitor 97.59% Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-144683 PF-07038124 Inhibitor / Phase 2
Inhibitory Antibodies (8)
Cat. No. Product Name Effect
Purity Phase
HY-P99496 Cendakimab Inhibitor 99.96% Phase 3
HY-P990093 Stapokibart Inhibitor 96.34% Phase 3
HY-P990090 Rademikibart Inhibitor / Phase 3
HY-P99870 Eblasakimab ≥99.0% Phase 2
HY-P99439 Anrukinzumab Inhibitor 98.64% Phase 2
HY-P99846 Dectrekumab / Phase 2
HY-P99883 Romilkimab / Phase 2
HY-P99417 Abrezekimab Inhibitor 95.00% Phase 1
Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-126360 Oxazolone ≥98.0% Unkown
HY-125019 iJak-381 Inhibitor 98.54% Unkown
HY-110295 SPL-334 Inhibitor / Unkown
HY-144683A PF-07038124 hydrochloride Inhibitor / Unkown
HY-144684 PDE4-IN-8 Inhibitor / Unkown
HY-162248 JAK1/2-IN-1 Inhibitor / Unkown
HY-165484 AVP-13358 Inhibitor / Unkown
HY-P10292 NOTA-Pep-1L / Unkown
HY-RS06685 IL13 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06686 Il13 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06687 Il13 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06688 IL13RA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06689 IL13RA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990748 Lunsekimig / Unkown
HY-P990699 Riltovetbart / Unkown
HY-P990735 Donzakimig / Unkown
HY-P990741 Galvokimig / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il13 NCBI NCBI:3596
Canis familiaris Il13 NCBI NCBI:442990
Macaca fascicularis Il13 NCBI NCBI:102125887
Rattus norvegicus Il13 NCBI NCBI:116553