EVI2A - ecotropic viral integration site 2A Gene

Homo sapiens

Also known as EVDA; EVI2; EVI-2A

Gene ID: 2123 | Gene type: protein coding

About EVI2A

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:31,316,410-31,321,622 (from NCBI)

This gene has 3 transcripts (splice variants) and 110 orthologues. Broad expression in brain (RPKM 20.1), appendix (RPKM 18.9) and 18 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

EVI2A Products(2)

mRNA	Protein	Name
NM_001003927.3	NP_001003927.1	protein EVI2A isoform 1
NM_014210.4	NP_055025.2	protein EVI2A isoform 2 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EVI2A Protein Structure

EVI2A

0
100
200
236 a.a.

Protein Preferred Names

Protein Names

protein EVI2A

ecotropic viral integration site 2A protein homolog

EVI2A Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	EVI2A	P22794	RTP2	Homo sapiens	Q5QGT7	Validated Y2H	32296183
Intra	EVI2A	P22794	PLPP4	Homo sapiens	Q5VZY2	Validated Y2H	32296183
Intra	EVI2A	P22794	UBIAD1	Homo sapiens	Q9Y5Z9	Validated Y2H	32296183
Intra	EVI2A	P22794	GOPC	Homo sapiens	Q9HD26	Anti Tag CoIP	33961781
Intra	EVI2A	P22794	PLP2	Homo sapiens	Q04941	Validated Y2H	32296183
Intra	EVI2A	P22794	ATP6V0C	Homo sapiens	P27449	Validated Y2H	32296183
Intra	EVI2A	P22794	MALL	Homo sapiens	Q13021	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant EVI2A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75757	EVI2A Protein, Human (HEK293, Fc)	P22794-1/NP_055025.2 (N31-M133)	≥95%

Related Diseases

Diseases

Alias

Chromosome 17q11.2 Deletion Syndrome

Nf1 Microdeletion Syndrome	17q11 Microdeletion Syndrome
Neurofibromatosis Type 1 Microdeletion Syndrome	Van Asperen Syndrome
Del(17)(Q11)	Monosomy 17q11
Chromosome 17q11.2 Deletion Syndrome, 1.4mb

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04574	EVI2A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	EVI2A	RGD	RGD:1593824
Mus musculus	EVI2A	MGD	MGI:95458

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