2. Gene
  3. EDC4 - enhancer of mRNA decapping 4 Gene

EDC4 - enhancer of mRNA decapping 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GE1; Ge-1; RCD8; HEDL5; HEDLS; RCD-8

Gene ID: 23644 | Gene type: protein coding

About EDC4

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,873,052-67,884,499 (from NCBI)

This gene has 14 transcripts (splice variants) and 212 orthologues. Ubiquitous expression in testis (RPKM 17.8), bone marrow (RPKM 15.0) and 25 other tissues.

Summary

Predicted to be involved in deadenylation-independent decapping of nuclear-transcribed mRNA. Located in P-body and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

EDC4 Products(1)

mRNA Protein Name
NM_014329.5 NP_055144.3 enhancer of mRNA-decapping protein 4
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15231747 GOA
Cellular Component GO Annotation Evidence Reference Source
located in P-body IDA
IDA: Inferred from direct assay
20826699 GOA
located in nucleus IDA
IDA: Inferred from direct assay
7520377 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

enhancer of mRNA-decapping protein 4

autoantigen Ge-1

Related Diseases

Diseases Alias
Human Granulocytic Anaplasmosis

Human Granulocytic Ehrlichiosis

Hge

Human Ehrlichial Infection, Human Granulocytic Type

Human Anaplasmosis Due To Anaplasma Phagocytophilum
Spherocytosis, Type 2

Hereditary Spherocytosis Type 2

SPH2

Spherocytosis, Hereditary, 2

Hs2

Hereditary Spherocytosis 2

Spherocytosis 2

Spherocytosis, Type 2, Autosomal Dominant
Ulnar Neuropathy

Ulnar Neuropathies
Thoracic Outlet Syndrome

Tos

Tos - Thoracic Outlet Syndrome

Thoracic Outlet Syndromes

Thoracic Outlet Compression Syndrome
Ehrlichiosis

Human Ehrlichiosis

He

Hey
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04156 EDC4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta EDC4 VGNC VGNC:72058
Bos taurus EDC4 VGNC VGNC:28321
Felis catus EDC4 VGNC VGNC:61721
Mus musculus EDC4 MGD MGI:2446249
Rattus norvegicus EDC4 RGD RGD:1562009
Canis familiaris EDC4 VGNC VGNC:40193